Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides

Bioscience, Biotechnology and Biochemistry

Volumn 83, Issue 2, 2019, Pages 185-191

  Sakakura, Ayaka ^a   Pauze, Martin ^a,b   Namiki, Atsuhiro ^a   Funakoshi Tago, Megumi ^a   Tamura, Hiroomi ^a   Hanaya, Kengo ^a   Higashibayashi, Shuhei ^a   Sugai, Takeshi ^a  

^a KEIO UNIVERSITY   (Japan)

^b Graduate School of SIGMA Clermont ^*  (France)

Author keywords

Anti inflammatory effect; Chemoselective acylation; Fatty acid monoesters; Hydroxytyrosol; Site selective hydroxylation

Indexed keywords

ACYLATION; HYDROXYLATION; NITRIC OXIDE; POLYSACCHARIDES;

ANTI-INFLAMMATORY EFFECTS; CHEMOSELECTIVE; HYDROXYTYROSOL; MONOESTERS; SITE SELECTIVE;

FATTY ACIDS;

3,4-DIHYDROXYPHENYLETHANOL; ESTER; FUNGAL PROTEIN; LIPASE B, CANDIDA ANTARCTICA; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHENETHYL ALCOHOL; TRIACYLGLYCEROL LIPASE;

ACYLATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HYDROXYLATION; IC50; METABOLISM; MOUSE; PROTON NUCLEAR MAGNETIC RESONANCE; RAW 264.7 CELL LINE; SYNTHESIS;

ACYLATION; ANIMALS; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; ESTERS; FUNGAL PROTEINS; HYDROXYLATION; INHIBITORY CONCENTRATION 50; LIPASE; LIPOPOLYSACCHARIDES; MICE; NITRIC OXIDE; PHENYLETHYL ALCOHOL; PROTON MAGNETIC RESONANCE SPECTROSCOPY; RAW 264.7 CELLS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 85060392114     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2018.1530970     Document Type: Article

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