Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation

Journal of Nutrition

Volumn 136, Issue 3, 2006, Pages 614-619

  Fabiani, Roberto ^a   De Bartolomeo, Angelo ^a   Rosignoli, Patrizia ^a   Servili, Maurizio ^a   Selvaggini, Roberto ^a   Montedoro, Gian Francesco ^a   Di Saverio, Cristina ^a   Morozzi, Guido ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Apoptosis; Chemoprevention; Differentiation; Olive oil; Phenols

Indexed keywords

3 [4,5 DIMETHYL(THIAZOL 2 YL)] 3,5 DIPHENYLTETRAZOLIUM BROMIDE; FORMAZAN; HYDROXYTYROSOL; NITROBLUE TETRAZOLIUM; OLIVE OIL; PHENOL; SUPEROXIDE; TYROSOL; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL COUNT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LEUKEMIA CELL; NUCLEAR MAGNETIC RESONANCE; PROMYELOCYTIC LEUKEMIA;

ANIMALIA;

EID: 33644847101     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.3.614     Document Type: Article

References (47)

1. Owen RW, Giacosa A, Hull WE, Haubner R, Würtele G, Spiegelhalder B, Bartsch H. Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol. 2000;1:107-12.
2. Martin-Moreno JM, Willett WC, Gorgojo L, Banegas JR, Rodriguez-Artalejo F, Fernandez-Rodriguez JC, Maisonneuve P, Boyle P. Dietary fat, olive oil intake and breast cancer risk. Int J Cancer. 1994;58:774-80.
3. Trichopoulou A, Katsouyanni K, Stuver S, Tzala L, Gnardellis C, Rimm E, Trichopoulos D. Consumption of olive oil and specific food groups in relation to breast cancer risk in Greece. J Natl Cancer Inst. 1995;87:110-6.
4. La Vecchia C, Negri E, Franceschi S, Decarli A, Giacosa A, Lipworth L. Olive oil, other dietary fats, and the risk of breast cancer (Italy). Cancer Causes Control. 1995;6:545-50.
5. Hodge AM, English DR, McCredie MR, Severi G, Boyle P, Hopper JL, Giles GG. Foods, nutrients and prostate cancer. Cancer Causes Control. 2004;15:11-20.
6. Fortes C, Forastiere F, Farchi S, Mallone S, Trequattrinni T, Anatra F, Schmid G, Perucci CA. The protective effect of the Mediterranean diet on lung cancer. Nutr Cancer. 2003;46:30-7.
7. Bosetti C, La Vecchia C, Talamini R, Negri E, Levi F, Dal Maso L, Franceschi S. Food groups and laryngeal cancer risk: a case-control study from Italy and Switzerland. Int J Cancer. 2002;100:355-60.
8. Bosetti C, Negri E, Franceschi S, Talamini R, Montella M, Conti E, Lagiou P, Parazzini F, La Vecchia C. Olive oil, seed oils and other added fats in relation to ovarian cancer (Italy). Cancer Causes Control. 2002;13:465-70.
9. Stoneham M, Goldacre M, Seagroatt V, Gill L. Olive oil, diet and colorectal cancer: an ecological study and a hypothesis. J Epidemiol Community Health. 2000;54:756-60.
10. Bartoli R, Fernandez-Banares F, Navarro E, Castella E, Mane J, Alvarez M, Pastor C, Cabre E, Gassull MA. Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E(2) synthesis. Gut. 2000;46:191-9.
11. Solanas M, Hurtado A, Costa I, Moral R, Menendez JA, Colomer R, Escrich E. Effects of a high olive oil diet on the clinical behavior and histopathological features of rat DMBA-induced mammary tumors compared with a high corn oil diet. Int J Oncol. 2002;21:745-53.
12. Thuy NT, He P, Takeuchi H. Comparative effect of dietary olive, safflower, and linseed oils on spontaneous liver tumorigenesis in C3H/He mice. J Nutr Sci Vitaminol (Tokyo). 2001;47:363-66.
13. Budiyanto A, Ahmed NU, Wu A, Bito T, Nikaido O, Osawa T, Ueda M, Ichihashi M. Protective effect of topically applied olive oil against photocarcinogenesis following UVB exposure of mice. Carcinogenesis. 2000;21:2085-90.
14. Vissers MN, Zock PL, Katan MB. Bioavailability and antioxidant effects of olive oil phenols in humans: a review. Eur J Clin Nutr. 2004;58:955-65.
15. Baldioli M, Servili M, Perretti G, Montedoro GF. Antioxidant activity of tocopherols and phenolic compounds of virgin olive oil. J Am Oil Chem Soc. 1996;73:1589-93.
16. Visioli F, Galli C. Biological properties of olive oil phytochemicals. Crit Rev Food Sci Nutr. 2002;42:209-21.
17. Servili M, Montedoro GF. Contribution of phenolic compounds to virgin olive oil quality. Eur J Lipid Sci Technol. 2002;104:602-13.
18. Owen RW, Mier W, Giacosa A, Hull WE, Spiegelhalder B, Bartsch H. Identification of lignans as major components in the phenolic fraction of olive oil. Clin Chem. 2000;46:976-88.
19. Fabiani R, De Bartolomeo A, Rosignoli P, Servili M, Montedoro GF, Morozzi G. Cancer chemoprevention by hydroxytyrosol isolated from virgin olive oil through G1 cell cycle arrest and apoptosis. Eur J Cancer Prev. 2002;11:351-58.
20. Ragione FD, Cucciolla V, Borriello A, Pietra VD, Pontoni G, Racioppi L, Manna C, Galletti P, Zappia V. Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome c-dependent apoptosis. Biochem Biophys Res Commun. 2000;278:733-39.
21. Montedoro GF, Servili M, Baldioli M, Miniati E. Simple and hydrolyzable compounds in virgin olive oil. 1. Their extraction, separation and quantitative and semiquantitative evaluation by HPLC. J Agric Food Chem. 1992;40:1571-76.
22. Montedoro GF, Servili M, Baldioli M, Selvaggini R, Miniati E, Macchioni A. Simple and hydrolyzable compounds in virgin olive oil. Note 3: Spectroscopic characterization of the secoiridoids derivatives. J Agric Food Chem. 1993;41:2228-34.
23. Hussain RF, Nouri AM, Oliver RT. A new approach for measurement of cytotoxicity using colorimetric assay. J Immunol Methods. 1993;160:89-96.
24. Hoorens A, Van de Casteele M, Kloppel G, Pipeleers D. Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest. 1996;98:1568-74.
25. Yamazaki A, Birnboim HC. Potentiation of retinoic acid-induced U-937 differentiation into respiratory burst-competent cells by nitric oxide donors. Leuk Res. 1995;19:325-35.
26. Kardono LB, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. J Nat Prod. 1990;53:1447-55.
27. Hirano T, Fukuoka K, Oka K, Naito T, Hosaka K, Mitsuhashi H, Matsumoto Y. Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer Invest. 1990;8:595-602.
28. Hausott B, Greger H, Marian B. Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells. J Cancer Res Clin Oncol. 2003;129:569-76.
29. Ragione FD, Cucciolla V, Borriello A, Pietra VD, Racioppi L, Soldati G, Manna C, Galletti P. Zappia V. Resveratrol arrests the cell division cycle at S/G2 phase transition. Biochem Biophys Res Commun. 1998;250:53-8.
30. Conney AH, Lou YR, Xie JG, Osawa T, Newmark HL, Liu Y, Chang RL, Huang MT. Some perspectives on dietary inhibition of carcinogenesis: studies with curcumin and tea. Proc Soc Exp Biol Med. 1997;216:234-45.
31. Hsu S, Bollag WB, Lewis J, Huang Q, Singh B, Sharawy M, Yamamoto T, Schuster G. Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J Pharmacol Exp Ther. 2003;306:29-34.
32. Suh N, Luyengi L, Fong HH, Kinghorn AD, Pezzuto JD. Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model. Anticancer Res. 1995;15:233-39.
33. Tsiftsoglou AS, Wong W, Hyman R, Minden M, Robinson SH. Analysis of commitment of human leukemia HL-60 cells to terminal granulocytic maturation. Cancer Res. 1985;45:2334-39.
34. Breitman TR, Selonick SE, Collins SJ. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci U S A. 1980;77:2936-40.
35. Castaigne S, Chomienne MT, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L. All-trans-retinoic acid as a differentiation therapy of acute promyelocytic leukemia. I. Clinical results. Blood. 1990;76:1704-9.
36. Hui EK, Yung BY. Cell cycle phase-dependent effect of retinoic acid on the induction of granulocytic differentiation in HL-60 promyelocytic leukemia cells. Evidence for sphinganine potentiation of retinoic acid-induced differentiation. FEBS Lett. 1993;318:193-99.
37. Myster DL, Duronio RJ. Cell cycle: to differentiate or not to differentiate? Curr Biol. 2000;10:R302-4.
38. Morgan DO. Principles of CDK regulation. Nature. 1995;374:131-4.
39. Sherr CJ. Cancer cell cycles. Science. 1996;274:1672-7.
40. Owen RW, Mier W, Giacosa A, Hull WE, Spiegelhalder B, Bartsch H. Phenolic compounds and squalene in olive oil: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoid, lignans and squalene. Food Chem Toxicol. 2000;38:647-59.
41. Briante R, Febbraio F, Nucci R. Antioxidant properties of low molecular weight phenols present in the Mediterranean diet. J Agric Food Chem. 2003;51:6975-81.
42. Toyokuni S, Okamoto K, Yodoi J, Hiai H. Persistent oxidative stress in cancer. FEBS Lett. 1995;358:1-3.
43. Boonstra J, Post JA. Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene. 2004;337:1-13.
44. Morimoto S, Shiraishi T, Fukuo K, Koh K, Kitano E, Yasuda O, Tamatani M, Ogihara T. EDTA induces differentiation and suppresses proliferation of promyelocitic leukemia cell line HL-60: possible participation of zinc. Biochem Int. 1992;28:313-21.
45. Miro-Casas E, Covas MI, Farre M, Fito M, Ortuno J, Weinbrenner T, Roset P, De la Torre R. Hydroxytyrosol disposition in humans. Clin Chem. 2003;49:945-52.
46. Weinbrenner T, Fitó M, De la Torre R, Saez GT, Rijken P, Tormos C, Coolen S, Albaladejo MF, Abanades S, et al. Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men. J Nutr. 2004;134:2314-21.
47. Marrugat J, Covas MI, Fitó M, Schroder H, Miro-Casas E, Gimeno E, Lopez-Sabater MC, De la Torre R, Farrè M, SOLOS Investigators. Effect of differing phenolic content in dietary olive oils on lipids and LDL oxidation. Eur J Nutr. 2004;43:140-7.