Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells

European Journal of Pharmacology

Volumn 834, Issue , 2018, Pages 246-256

  Funakohi Tago, Megumi ^a   Sakata, Tomoki ^a   Fujiwara, Satoru ^a   Sakakura, Ayaka ^a   Sugai, Takeshi ^a   Tago, Kenji ^b   Tamura, Hiroomi ^a  

^a KEIO UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Antioxidant activity; HO 1; Hydroxytyrosol butyrate; Keap1; Nrf2

Indexed keywords

CASPASE 3; CYSTEINE; ESTER DERIVATIVE; HEME OXYGENASE 1; HYDROXYTYROSOL; HYDROXYTYROSOL ACETATE; HYDROXYTYROSOL BUTYRATE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; NEUROPROTECTIVE AGENT; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLETHANOL; PHENETHYL ALCOHOL;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; GENE ACTIVATION; GENE EXPRESSION REGULATION; HO 1 GENE; HUMAN; HUMAN CELL; NEUROPROTECTION; NRF2 GENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESIDUE ANALYSIS; SH-SY5Y CELL LINE; TRANSACTIVATION; TRANSCRIPTION INITIATION; UPREGULATION; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECT; GENETICS; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HUMANS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDOPAMINE; PHENYLETHYL ALCOHOL; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION;

EID: 85050622802     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2018.07.043     Document Type: Article

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