메뉴 건너뛰기




Volumn 30, Issue 6, 2018, Pages 307-322

A brief history of antidepressant drug development: From tricyclics to beyond ketamine

Author keywords

AMPA receptors; antidepressant drugs; brain derived neurotrophic factor; ketamine; N methyl D aspartate receptors

Indexed keywords

BIOLOGICAL MARKER; FLUOXETINE; KETAMINE; MIRTAZAPINE; NEFAZODONE; REBOXETINE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE; BIOGENIC AMINE;

EID: 85058605868     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1017/neu.2017.39     Document Type: Review
Times cited : (84)

References (154)
  • 2
    • 33645452696 scopus 로고    scopus 로고
    • Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
    • MILLAN MJ. Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application. Pharmacol Ther 2006;110:135-370.
    • (2006) Pharmacol Ther , vol.110 , pp. 135-370
    • Millan, M.J.1
  • 3
    • 0036325685 scopus 로고    scopus 로고
    • Beyond the monoamine hypothesis: Mechanisms, molecules and methods
    • HINDMARCH I. Beyond the monoamine hypothesis: mechanisms, molecules and methods. Eur Psychiatry 2002;17(Suppl. 3): 294-299.
    • (2002) Eur Psychiatry , vol.17 , pp. 294-299
    • Hindmarch, I.1
  • 4
    • 0033969685 scopus 로고    scopus 로고
    • Antidepressant effects of ketamine in depressed patients
    • BERMAN RM, CAPPIELLO A, ANAND A et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000;47:351-354.
    • (2000) Biol Psychiatry , vol.47 , pp. 351-354
    • Berman, R.M.1    Cappiello, A.2    Anand, A.3
  • 6
    • 85008618964 scopus 로고    scopus 로고
    • Ketamine: Translating mechanistic discoveries into the next generation of glutamate modulators for mood disorders
    • ZARATE CA JR., MACHADO-VIEIRA R. Ketamine: translating mechanistic discoveries into the next generation of glutamate modulators for mood disorders. Mol Psychiatry 2017; 22:324-327.
    • (2017) Mol Psychiatry , vol.22 , pp. 324-327
    • Zarate, C.A.J.R.1    MacHado-Vieira, R.2
  • 7
    • 84891713774 scopus 로고    scopus 로고
    • Antidepressant effects of ketamine: Mechanisms underlying fast-acting novel antidepressants
    • BROWNE CA, LUCKI I. Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants. Front Pharmacol 2013;4:161.
    • (2013) Front Pharmacol , vol.4 , pp. 161
    • Browne, C.A.1    Lucki, I.2
  • 8
    • 0035034844 scopus 로고    scopus 로고
    • Pharmacotherapy of mental illness - A historical analysis
    • BAN TA. Pharmacotherapy of mental illness - a historical analysis. Prog Neuropsychopharmacol Biol Psychiatry 2001;25:709-727.
    • (2001) Prog Neuropsychopharmacol Biol Psychiatry , vol.25 , pp. 709-727
    • Ban, T.A.1
  • 10
    • 0030939221 scopus 로고    scopus 로고
    • The history of the psychopharmacology of schizophrenia
    • LEHMANN HE, BAN TA. The history of the psychopharmacology of schizophrenia. Can J Psychiatry 1997;42: 152-162.
    • (1997) Can J Psychiatry , vol.42 , pp. 152-162
    • Lehmann, H.E.1    Ban, T.A.2
  • 11
    • 84980004949 scopus 로고    scopus 로고
    • Daniel Bovet, Nobelist: Muscle relaxants in anaesthesia: The role played by two neglected protagonists
    • COZANITIS DA. Daniel Bovet, Nobelist: muscle relaxants in anaesthesia: the role played by two neglected protagonists. Wien Med Wochenschr 2016;166:487-499.
    • (2016) Wien Med Wochenschr , vol.166 , pp. 487-499
    • Cozanitis, D.A.1
  • 12
    • 0032864985 scopus 로고    scopus 로고
    • History of modern psychopharmacology: A personal view with an emphasis on antidepressants
    • DOMINO EF. History of modern psychopharmacology: a personal view with an emphasis on antidepressants. Psychosom Med 1999;61:591-598.
    • (1999) Psychosom Med , vol.61 , pp. 591-598
    • Domino, E.F.1
  • 13
    • 0000876391 scopus 로고
    • The treatment of depressive states with G 22355 (imipramine hydrochloride)
    • KUHN R. The treatment of depressive states with G 22355 (imipramine hydrochloride). Am J Psychiatry 1958;115: 459-464.
    • (1958) Am J Psychiatry , vol.115 , pp. 459-464
    • Kuhn, R.1
  • 15
    • 33750131855 scopus 로고    scopus 로고
    • In memory of three pioneers
    • BAN TA. In memory of three pioneers. Int J Neuropsychopharmacol 2006;9:475-477.
    • (2006) Int J Neuropsychopharmacol , vol.9 , pp. 475-477
    • Ban, T.A.1
  • 16
    • 0000960697 scopus 로고
    • Influence of isonicotinic acid hydrazide (Inh) and 1-isonicotinyl-2-isopropyl hydrazide (Iih) on bacterial and mammalian enzymes
    • ZELLER EA, BARSKY J, FOUTS JR, KIRCHHEIMER WF, VANORDEN LS. Influence of isonicotinic acid hydrazide (Inh) and 1-isonicotinyl-2-isopropyl hydrazide (Iih) on bacterial and mammalian enzymes. Experientia 1952;8:349-350.
    • (1952) Experientia , vol.8 , pp. 349-350
    • Zeller, E.A.1    Barsky, J.2    Fouts, J.R.3    Kirchheimer, W.F.4    Vanorden, L.S.5
  • 17
    • 67650591254 scopus 로고    scopus 로고
    • Monoaminergic neurotransmission: The history of the discovery of antidepressants from 1950s until today
    • LOPEZ-MUNOZ F, ALAMO C. Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today. Curr Pharm Des 2009;15:1563-1586.
    • (2009) Curr Pharm des , vol.15 , pp. 1563-1586
    • Lopez-Munoz, F.1    Alamo, C.2
  • 18
    • 0004500264 scopus 로고
    • Anxiety and depressive states treated with isonicotinyl hydrazide (isoniazid)
    • SALZER HM, LURIE ML. Anxiety and depressive states treated with isonicotinyl hydrazide (isoniazid). AMA Arch Neurol Psychiatry 1953;70:317-324.
    • (1953) AMA Arch Neurol Psychiatry , vol.70 , pp. 317-324
    • Salzer, H.M.1    Lurie, M.L.2
  • 19
    • 85059869013 scopus 로고
    • Drug discovery; The evolution of modern medicines
    • LEWIS JG. Drug discovery; the evolution of modern medicines. Postgraduate Med J 1986;62:704.
    • (1986) Postgraduate Med J , vol.62 , pp. 704
    • Lewis, J.G.1
  • 20
    • 38349084850 scopus 로고    scopus 로고
    • Half a century of antidepressant drugs: On the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part I: Monoamine oxidase inhibitors
    • LOPEZ-MUNOZ F, ALAMO C, JUCKEL G, ASSION HJ. Half a century of antidepressant drugs: on the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part I: monoamine oxidase inhibitors. J Clin Psychopharmacol 2007;27:555-559.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 555-559
    • Lopez-Munoz, F.1    Alamo, C.2    Juckel, G.3    Assion, H.J.4
  • 21
    • 0002543345 scopus 로고
    • Pharmacological studies with Tofranil
    • SIGG EB. Pharmacological studies with Tofranil. Can Psychiatr Assoc J 1959;4(Suppl.):75-85.
    • (1959) Can Psychiatr Assoc J , vol.4 , pp. 75-85
    • Sigg, E.B.1
  • 22
    • 0001570664 scopus 로고
    • Effect of drugs on the uptake and metabolism of H3-norepinephrine
    • HERTING G, AXELROD J, WHITBY LG. Effect of drugs on the uptake and metabolism of H3-norepinephrine. J Pharmacol Exp Ther 1961;134:146-153.
    • (1961) J Pharmacol Exp Ther , vol.134 , pp. 146-153
    • Herting, G.1    Axelrod, J.2    Whitby, L.G.3
  • 23
    • 0000264756 scopus 로고
    • The catecholamine hypothesis of affective disorders: A review of supporting evidence
    • SCHILDKRAUT JJ. The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 1965;122:509-522.
    • (1965) Am J Psychiatry , vol.122 , pp. 509-522
    • Schildkraut, J.J.1
  • 24
    • 20244386667 scopus 로고
    • Catecholamine metabolism in affective disorders. I. Normetanephrine and VMA excretion in depressed patients treated with imipramine
    • SCHILDKRAUT JJ, GORDON EK, DURELL J. Catecholamine metabolism in affective disorders. I. Normetanephrine and VMA excretion in depressed patients treated with imipramine. J Psychiatr Res 1965;3:213-228.
    • (1965) J Psychiatr Res , vol.3 , pp. 213-228
    • Schildkraut, J.J.1    Gordon, E.K.2    Durell, J.3
  • 25
    • 0014150508 scopus 로고
    • The biochemistry of affective disorders
    • COPPEN A. The biochemistry of affective disorders. Br J Psychiatry 1967;113:1237-1264.
    • (1967) Br J Psychiatry , vol.113 , pp. 1237-1264
    • Coppen, A.1
  • 26
    • 0013913572 scopus 로고
    • The role of brain serotonin in the mechanism of the central action of reserpine
    • BRODIE BB, COMER MS, COSTA E, DLABAC A. The role of brain serotonin in the mechanism of the central action of reserpine. J Pharmacol Exp Ther 1966;152:340-349.
    • (1966) J Pharmacol Exp Ther , vol.152 , pp. 340-349
    • Brodie, B.B.1    Comer, M.S.2    Costa, E.3    Dlabac, A.4
  • 27
    • 0017161279 scopus 로고
    • Parachlorophenylalanine reversal of tranylcypromine effects in depressed patients
    • SHOPSIN B, FRIEDMAN E, GERSHON S. Parachlorophenylalanine reversal of tranylcypromine effects in depressed patients. Arch Gen Psychiatry 1976;33:811-819.
    • (1976) Arch Gen Psychiatry , vol.33 , pp. 811-819
    • Shopsin, B.1    Friedman, E.2    Gershon, S.3
  • 28
    • 0016731963 scopus 로고
    • Use of synthesis inhibitors in defining a role for biogenic amines during imipramine treatment in depressed patients
    • SHOPSIN B, GERSHON S, GOLDSTEIN M, FRIEDMAN E, WILK S. Use of synthesis inhibitors in defining a role for biogenic amines during imipramine treatment in depressed patients. Psychopharmacol Commun 1975;1:239-249.
    • (1975) Psychopharmacol Commun , vol.1 , pp. 239-249
    • Shopsin, B.1    Gershon, S.2    Goldstein, M.3    Friedman, E.4    Wilk, S.5
  • 29
    • 50549205358 scopus 로고
    • Potentiation of the antidepressive effect of a monoamine-oxidase inhibitor by tryptophan
    • COPPEN A, SHAW DM, FARRELL JP. Potentiation of the antidepressive effect of a monoamine-oxidase inhibitor by tryptophan. Lancet 1963;1:79-81.
    • (1963) Lancet , vol.1 , pp. 79-81
    • Coppen, A.1    Shaw, D.M.2    Farrell, J.P.3
  • 30
    • 0014682651 scopus 로고
    • Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect
    • LAPIN IP, OXENKRUG GF. Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect. Lancet 1969;1:132-136.
    • (1969) Lancet , vol.1 , pp. 132-136
    • Lapin, I.P.1    Oxenkrug, G.F.2
  • 31
    • 0034922165 scopus 로고    scopus 로고
    • Pharmacotherapy of depression: A historical analysis
    • BAN TA. Pharmacotherapy of depression: a historical analysis. J Neural Transm (Vienna) 2001;108:707-716.
    • (2001) J Neural Transm (Vienna) , vol.108 , pp. 707-716
    • Ban, T.A.1
  • 32
    • 0003022711 scopus 로고
    • The imipramine story
    • Ayd FJ editor. Philadelphia: JB Lippincott
    • KUHN R. The imipramine story. In: Ayd FJ editor Discoveries in biological psychiatry. Philadelphia: JB Lippincott, 1970; p. 205-217.
    • (1970) Discoveries in Biological Psychiatry , pp. 205-217
    • Kuhn, R.1
  • 33
    • 84940127834 scopus 로고
    • Desmethylimipramine, a new type of antidepressant drug
    • BRODIE BB, BICKEL MH, SULSER F. Desmethylimipramine, a new type of antidepressant drug. Med Exp Int J Exp Med 1961;5:454-458.
    • (1961) Med Exp Int J Exp Med , vol.5 , pp. 454-458
    • Brodie, B.B.1    Bickel, M.H.2    Sulser, F.3
  • 34
    • 38349155456 scopus 로고    scopus 로고
    • Half a century of antidepressant drugs: On the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part II: Tricyclics and tetracyclics
    • FANGMANN P, ASSION HJ, JUCKEL G, GONZALEZ CA, LOPEZMUNOZ F. Half a century of antidepressant drugs: on the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part II: tricyclics and tetracyclics. J Clin Psychopharmacol 2008;28:1-4.
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 1-4
    • Fangmann, P.1    Assion, H.J.2    Juckel, G.3    Gonzalez, C.A.4    Lopezmunoz, F.5
  • 35
    • 80051966985 scopus 로고    scopus 로고
    • IMS Institute for Healthcare Informatics. Kleinrock M, editor. Parsippany, NJ, USA: IMS Institute for Healthcare Informatics
    • IMS Institute for Healthcare Informatics. The use of medicines in the United States: review of 2011. In: Kleinrock M, editor. Parsippany, NJ, USA: IMS Institute for Healthcare Informatics, 2011.
    • (2011) The Use of Medicines in the United States: Review of 2011
  • 36
    • 84903433638 scopus 로고    scopus 로고
    • Antidepressant prescribing in five European countries: Application of common definitions to assess the prevalence, clinical observations, and methodological implications
    • ABBING-KARAHAGOPIAN V, HUERTA C, SOUVEREIN PC et al. Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications. Eur J Clin Pharmacol. 2014;70:849-857.
    • (2014) Eur J Clin Pharmacol , vol.70 , pp. 849-857
    • Abbing-Karahagopian, V.1    Huerta, C.2    Souverein, P.C.3
  • 37
    • 0016197944 scopus 로고
    • A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpro pylamine
    • WONG DT, HORNG JS, BYMASTER FP, HAUSER KL, MOLLOY BB. A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpro pylamine. Life Sci 1974;15:471-479.
    • (1974) Life Sci , vol.15 , pp. 471-479
    • Wong, D.T.1    Horng, J.S.2    Bymaster, F.P.3    Hauser, K.L.4    Molloy, B.B.5
  • 38
    • 85059866362 scopus 로고    scopus 로고
    • Cuenca El triunfo de la política de diseño racional de psicofármacos: Descubrimiento de la fluoxetina
    • 2.1 edn. Madrid: Panamericana
    • LÓPEZ-MUÑOZ F, ÁLAMO C. Cuenca El triunfo de la política de diseño racional de psicofármacos: descubrimiento de la fluoxetina. In: Historia De La Psicofarmacologia, Vol 2, 2.1 edn. Madrid: Panamericana, 2007. p. 1195.
    • (2007) Historia de la Psicofarmacologia , vol.2 , pp. 1195
    • López-Muñoz, F.1    Álamo, C.2
  • 39
    • 0013669976 scopus 로고
    • The efficacy of fluoxetine as an antidepressant in the short and long term
    • SAM
    • SAM. The efficacy of fluoxetine as an antidepressant in the short and long term. Int Clin Psychopharmacol 1989; 4(Suppl. 1):113-119.
    • (1989) Int Clin Psychopharmacol , vol.4 , pp. 113-119
  • 41
    • 0032542541 scopus 로고    scopus 로고
    • Prescribing trends in psychotropic medications: Primary care, psychiatry, and other medical specialties
    • PINCUS HA, TANIELIAN TL, MARCUS SC et al. Prescribing trends in psychotropic medications: primary care, psychiatry, and other medical specialties. JAMA 1998;279:526-531.
    • (1998) JAMA , vol.279 , pp. 526-531
    • Pincus, H.A.1    Tanielian, T.L.2    Marcus, S.C.3
  • 42
    • 0035817529 scopus 로고    scopus 로고
    • The career of a celebrity pill. As Prozac's long reign comes to an end, experts are questioning its legacy
    • SZEGEDY-MASZAK M. The career of a celebrity pill. As Prozac's long reign comes to an end, experts are questioning its legacy. US News World Rep 2001;131:38-39.
    • (2001) US News World Rep , vol.131 , pp. 38-39
    • Szegedy-Maszak, M.1
  • 43
    • 0036271771 scopus 로고    scopus 로고
    • The Prozac boom and its placebogenic counterpart - A culturally fashioned phenomenon
    • SLINGSBY BT. The Prozac boom and its placebogenic counterpart - a culturally fashioned phenomenon. Med Sci Monit 2002;8:CR389-CR393.
    • (2002) Med Sci Monit , vol.8 , pp. CR389-CR393
    • Slingsby, B.T.1
  • 44
    • 0032191019 scopus 로고    scopus 로고
    • Antidepressant treatments in the 21st century
    • NESTLER EJ. Antidepressant treatments in the 21st century. Biol Psychiatry 1998;44:526-533.
    • (1998) Biol Psychiatry , vol.44 , pp. 526-533
    • Nestler, E.J.1
  • 45
    • 0347481324 scopus 로고    scopus 로고
    • Monoamine depletion in psychiatric and healthy populations: Review
    • BOOIJ L, VAN DER DOES AJ, RIEDEL WJ. Monoamine depletion in psychiatric and healthy populations: review. Mol Psychiatry 2003;8:951-973.
    • (2003) Mol Psychiatry , vol.8 , pp. 951-973
    • Booij, L.1    Van Der-Does, A.J.2    Riedel, W.J.3
  • 46
    • 33646801936 scopus 로고    scopus 로고
    • Monoamine depletion studies: Implications for antidepressant discontinuation syndrome
    • DELGADO PL. Monoamine depletion studies: implications for antidepressant discontinuation syndrome. J Clin Psychiatry 2006;67(Suppl. 4):22-26.
    • (2006) J Clin Psychiatry , vol.67 , pp. 22-26
    • Delgado, P.L.1
  • 47
    • 71549120694 scopus 로고    scopus 로고
    • CSF neurochemicals during tryptophan depletion in individuals with remitted depression and healthy controls
    • MORENO FA, PARKINSON D, PALMER C et al. CSF neurochemicals during tryptophan depletion in individuals with remitted depression and healthy controls. Eur Neuropsychopharmacol 2010;20:18-24.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 18-24
    • Moreno, F.A.1    Parkinson, D.2    Palmer, C.3
  • 48
    • 33744930691 scopus 로고
    • A review of one hundred and forty-four cases of affective disorders - After seven years
    • HOHMAN LB. A review of one hundred and forty-four cases of affective disorders - after seven years. Am J Psychiatry 1937;94:303-308.
    • (1937) Am J Psychiatry , vol.94 , pp. 303-308
    • Hohman, L.B.1
  • 49
    • 84870360228 scopus 로고    scopus 로고
    • Treatment-resistant depression: Therapeutic trends, challenges, and future directions
    • AL-HARBI KS. Treatment-resistant depression: therapeutic trends, challenges, and future directions. Patient Prefer Adherence 2012;6:369-388.
    • (2012) Patient Prefer Adherence , vol.6 , pp. 369-388
    • Al-Harbi, K.S.1
  • 50
    • 33847306465 scopus 로고    scopus 로고
    • Beyond the evidence: Is there a place for antidepressant combinations in the pharmacotherapy of depression?
    • KEKS NA, BURROWS GD, COPOLOV DL et al. Beyond the evidence: is there a place for antidepressant combinations in the pharmacotherapy of depression? Med J Aust 2007;186:142-144.
    • (2007) Med J Aust , vol.186 , pp. 142-144
    • Keks, N.A.1    Burrows, G.D.2    Copolov, D.L.3
  • 51
    • 85042272604 scopus 로고    scopus 로고
    • World Health Organization CGF. Geneva: World Health Organization, Accessed April 10, 2017
    • World Health Organization CGF. Improving access and appropriate use of medicines for mental disorders. Geneva: World Health Organization, 2017; Available at http:// apps.who.int/iris/bitstream/10665/254794/1/9789241511421-eng.pdf. Accessed April 10, 2017.
    • (2017) Improving Access and Appropriate Use of Medicines for Mental Disorders
  • 52
    • 0000174201 scopus 로고
    • The synthesis of phencyclidine and other 1-arylcyclohexylamines
    • MADDOX VH, GODEFROI EF, PARCELL RF. The synthesis of phencyclidine and other 1-arylcyclohexylamines. J Med Chem 1965;8:230-235.
    • (1965) J Med Chem , vol.8 , pp. 230-235
    • Maddox, V.H.1    Godefroi, E.F.2    Parcell, R.F.3
  • 53
    • 77957008254 scopus 로고    scopus 로고
    • Taming the ketamine tiger. 1965
    • DOMINO EF. Taming the ketamine tiger. 1965. Anesthesiology 2010;113:678-684.
    • (2010) Anesthesiology , vol.113 , pp. 678-684
    • Domino, E.F.1
  • 54
    • 0020121391 scopus 로고
    • Phencyclidine (PCP): A review and perspectives
    • ANILINE O, PITTS FN JR. Phencyclidine (PCP): a review and perspectives. Crit Rev Toxicol 1982;10:145-177.
    • (1982) Crit Rev Toxicol , vol.10 , pp. 145-177
    • Aniline, O.1    Pitts, F.N.J.R.2
  • 55
    • 77952810889 scopus 로고
    • Pharmacologic effects of Ci-581, a new dissociative anesthetic, in man
    • DOMINO EF, CHODOFF P, CORSSEN G. Pharmacologic effects of Ci-581, a new dissociative anesthetic, in man. Clin Pharmacol Ther 1965;6:279-291.
    • (1965) Clin Pharmacol Ther , vol.6 , pp. 279-291
    • Domino, E.F.1    Chodoff, P.2    Corssen, G.3
  • 56
    • 0014270573 scopus 로고
    • Ketamine (Cl-581) in clinical anaesthesia
    • GJESSING J. Ketamine (Cl-581) in clinical anaesthesia. Acta Anaesthesiol Scand 1968;12:15-21.
    • (1968) Acta Anaesthesiol Scand , vol.12 , pp. 15-21
    • Gjessing, J.1
  • 57
    • 0014443698 scopus 로고
    • Electroencephalographic effects of ketamine anesthesia in children
    • CORSSEN G, DOMINO EF, BREE RL. Electroencephalographic effects of ketamine anesthesia in children. Anesth Analg 1969;48:141-147.
    • (1969) Anesth Analg , vol.48 , pp. 141-147
    • Corssen, G.1    Domino, E.F.2    Bree, R.L.3
  • 59
    • 0015459793 scopus 로고
    • Ketamine anaesthesia in paediatric procedures
    • PAGE P, MORGAN M, LOH L. Ketamine anaesthesia in paediatric procedures. Acta Anaesthesiol Scand 1972;16:155-160.
    • (1972) Acta Anaesthesiol Scand , vol.16 , pp. 155-160
    • Page, P.1    Morgan, M.2    Loh, L.3
  • 60
    • 0016365726 scopus 로고
    • A comparative evaluation of ketamine anesthesia in children and adults
    • SUSSMAN DR. A comparative evaluation of ketamine anesthesia in children and adults. Anesthesiology 1974;40:459-464.
    • (1974) Anesthesiology , vol.40 , pp. 459-464
    • Sussman, D.R.1
  • 61
    • 84878198012 scopus 로고    scopus 로고
    • From "special K" to "special M": The evolution of the recreational use of ketamine and methoxetamine
    • CORAZZA O, ASSI S, SCHIFANO F. From "Special K" to "Special M": the evolution of the recreational use of ketamine and methoxetamine. CNS Neurosci Ther 2013; 19:454-460.
    • (2013) CNS Neurosci Ther , vol.19 , pp. 454-460
    • Corazza, O.1    Assi, S.2    Schifano, F.3
  • 62
    • 84926658459 scopus 로고    scopus 로고
    • Ketamine: Promising path or false prophecy in the development of novel therapeutics for mood disorders?
    • SANACORA G, SCHATZBERG AF. Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? Neuropsychopharmacology 2015;40:259-267.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 259-267
    • Sanacora, G.1    Schatzberg, A.F.2
  • 64
    • 0020629581 scopus 로고
    • The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methylaspartate
    • ANIS NA, BERRY SC, BURTON NR, LODGE D. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methylaspartate. Br J Pharmacol 1983;79:565-575.
    • (1983) Br J Pharmacol , vol.79 , pp. 565-575
    • Anis, N.A.1    Berry, S.C.2    Burton, N.R.3    Lodge, D.4
  • 65
    • 0022005967 scopus 로고
    • Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex
    • HARRISON NL, SIMMONDS MA. Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. Br J Pharmacol 1985;84:381-391.
    • (1985) Br J Pharmacol , vol.84 , pp. 381-391
    • Harrison, N.L.1    Simmonds, M.A.2
  • 66
    • 84878124776 scopus 로고    scopus 로고
    • Ketamine in pain management
    • PERSSON J. Ketamine in pain management. CNS Neurosci Ther 2013;19:396-402.
    • (2013) CNS Neurosci Ther , vol.19 , pp. 396-402
    • Persson, J.1
  • 67
    • 84914163515 scopus 로고    scopus 로고
    • Recent insights into the mode of action of memantine and ketamine
    • JOHNSON JW, GLASGOW NG, POVYSHEVA NV. Recent insights into the mode of action of memantine and ketamine. Curr Opin Pharmacol 2015;20:54-63.
    • (2015) Curr Opin Pharmacol , vol.20 , pp. 54-63
    • Johnson, J.W.1    Glasgow, N.G.2    Povysheva, N.V.3
  • 69
    • 0025157918 scopus 로고
    • Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
    • TRULLAS R, SKOLNICK P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur J Pharmacol 1990;185:1-10.
    • (1990) Eur J Pharmacol , vol.185 , pp. 1-10
    • Trullas, R.1    Skolnick, P.2
  • 70
    • 0027231058 scopus 로고
    • Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: Comparison to hippocampus and basal ganglia
    • MOGHADDAM B. Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem 1993;60:1650-1657.
    • (1993) J Neurochem , vol.60 , pp. 1650-1657
    • Moghaddam, B.1
  • 71
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • MOGHADDAM B, ADAMS B, VERMA A, DALY D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 1997;17:2921-2927.
    • (1997) J Neurosci , vol.17 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 72
    • 0037093781 scopus 로고    scopus 로고
    • Stress activation of glutamate neurotransmission in the prefrontal cortex: Implications for dopamine-associated psychiatric disorders
    • MOGHADDAM B. Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders. Biol Psychiatry 2002;51:775-787.
    • (2002) Biol Psychiatry , vol.51 , pp. 775-787
    • Moghaddam, B.1
  • 73
    • 0027432521 scopus 로고
    • Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid
    • NOWAK G, TRULLAS R, LAYER RT, SKOLNICK P, PAUL IA. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. J Pharmacol Exp Ther 1993;265:1380-1386.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1380-1386
    • Nowak, G.1    Trullas, R.2    Layer, R.T.3    Skolnick, P.4    Paul, I.A.5
  • 74
    • 0030032399 scopus 로고    scopus 로고
    • Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: Implications for the pharmacotherapy of depression
    • SKOLNICK P, LAYER RT, POPIK P, NOWAK G, PAUL IA, TRULLAS R. Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression. Pharmacopsychiatry 1996;29:23-26.
    • (1996) Pharmacopsychiatry , vol.29 , pp. 23-26
    • Skolnick, P.1    Layer, R.T.2    Popik, P.3    Nowak, G.4    Paul, I.A.5    Trullas, R.6
  • 75
    • 84878409579 scopus 로고    scopus 로고
    • Rapid-acting glutamatergic antidepressants: The path to ketamine and beyond
    • KRYSTAL JH, SANACORA G, DUMAN RS. Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biol Psychiatry 2013;73:1133-1141.
    • (2013) Biol Psychiatry , vol.73 , pp. 1133-1141
    • Krystal, J.H.1    Sanacora, G.2    Duman, R.S.3
  • 76
    • 84921341863 scopus 로고    scopus 로고
    • Ketamine and rapid-acting antidepressants: A window into a new neurobiology for mood disorder therapeutics
    • ABDALLAH CG, SANACORA G, DUMAN RS, KRYSTAL JH. Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics. Annu Rev Med 2015;66:509-523.
    • (2015) Annu Rev Med , vol.66 , pp. 509-523
    • Abdallah, C.G.1    Sanacora, G.2    Duman, R.S.3    Krystal, J.H.4
  • 77
    • 33746896935 scopus 로고    scopus 로고
    • A randomized trial of an N-methyl-D-aspartate antagonist in treatmentresistant major depression
    • ZARATE CA JR., SINGH JB, CARLSON PJ et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatmentresistant major depression. Arch Gen Psychiatry 2006; 63:856-864.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 856-864
    • Zarate, C.A.J.R.1    Singh, J.B.2    Carlson, P.J.3
  • 78
    • 84864286398 scopus 로고    scopus 로고
    • Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression
    • ZARATE CA JR., BRUTSCHE N, LAJE G et al. Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biol Psychiatry 2012; 72:331-338.
    • (2012) Biol Psychiatry , vol.72 , pp. 331-338
    • Zarate, C.A.J.R.1    Brutsche, N.2    Laje, G.3
  • 79
    • 84861099072 scopus 로고    scopus 로고
    • Replication of ketamine's antidepressant efficacy in bipolar depression: A randomized controlled add-on trial
    • ZARATE CA JR., BRUTSCHE NE, IBRAHIM L et al. Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial. Biol Psychiatry 2012; 71:939-946.
    • (2012) Biol Psychiatry , vol.71 , pp. 939-946
    • Zarate, C.A.J.R.1    Brutsche, N.E.2    Ibrahim, L.3
  • 80
    • 77955909841 scopus 로고    scopus 로고
    • MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
    • LI N, LEE B, LIU RJ et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010;329:959-964.
    • (2010) Science , vol.329 , pp. 959-964
    • Li, N.1    Lee, B.2    Liu, R.J.3
  • 81
    • 79960057257 scopus 로고    scopus 로고
    • NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
    • AUTRY AE, ADACHI M, NOSYREVA E et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 2011;475:91-95.
    • (2011) Nature , vol.475 , pp. 91-95
    • Autry, A.E.1    Adachi, M.2    Nosyreva, E.3
  • 82
    • 79953166373 scopus 로고    scopus 로고
    • Glutamate N-methyl-Daspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
    • LI N, LIU RJ, DWYER JM et al. Glutamate N-methyl-Daspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry 2011;69:754-761.
    • (2011) Biol Psychiatry , vol.69 , pp. 754-761
    • Li, N.1    Liu, R.J.2    Dwyer, J.M.3
  • 83
    • 84930867573 scopus 로고    scopus 로고
    • Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test
    • PEREIRA VS, ROMANO A, WEGENER G, JOCA SR. Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test. Psychopharmacology (Berl) 2015;232:2263-2273.
    • (2015) Psychopharmacology (Berl) , vol.232 , pp. 2263-2273
    • Pereira, V.S.1    Romano, A.2    Wegener, G.3    Joca, S.R.4
  • 84
    • 0029013930 scopus 로고
    • Muscarinic acetylcholine receptors: Signal transduction through multiple effectors
    • FELDER CC. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 1995; 9:619-625.
    • (1995) FASEB J , vol.9 , pp. 619-625
    • Felder, C.C.1
  • 85
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • ALDERTON WK, COOPER CE, KNOWLES RG. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001;357:593-615.
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 86
    • 84884712063 scopus 로고    scopus 로고
    • Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats
    • RAHIMIAN R, FAKHFOURI G, EJTEMAEI MEHR S et al. Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats. Eur J Clin Invest 2013;43:1039-1051.
    • (2013) Eur J Clin Invest , vol.43 , pp. 1039-1051
    • Rahimian, R.1    Fakhfouri, G.2    Ejtemaei Mehr, S.3
  • 89
    • 0024462440 scopus 로고
    • NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices
    • GARTHWAITE J, GARTHWAITE G, PALMER RM, MONCADA S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 1989; 172:413-416.
    • (1989) Eur J Pharmacol , vol.172 , pp. 413-416
    • Garthwaite, J.1    Garthwaite, G.2    Palmer, R.M.3    Moncada, S.4
  • 90
    • 24144494527 scopus 로고    scopus 로고
    • The physiology and pathophysiology of nitric oxide in the brain
    • GUIX FX, URIBESALGO I, COMA M, MUNOZ FJ. The physiology and pathophysiology of nitric oxide in the brain. Prog Neurobiol 2005;76:126-152.
    • (2005) Prog Neurobiol , vol.76 , pp. 126-152
    • Guix, F.X.1    Uribesalgo, I.2    Coma, M.3    Munoz, F.J.4
  • 93
    • 0030050964 scopus 로고    scopus 로고
    • Nitric oxide modulates retention of immobility in the forced swimming test in rats
    • JEFFERYS D, FUNDER J. Nitric oxide modulates retention of immobility in the forced swimming test in rats. Eur J Pharmacol 1996;295:131-135.
    • (1996) Eur J Pharmacol , vol.295 , pp. 131-135
    • Jefferys, D.1    Funder, J.2
  • 94
    • 0034110759 scopus 로고    scopus 로고
    • Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats
    • YILDIZ F, ERDEN BF, ULAK G, UTKAN T, GACAR N. Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology (Berl) 2000; 149:41-44.
    • (2000) Psychopharmacology (Berl) , vol.149 , pp. 41-44
    • Yildiz, F.1    Erden, B.F.2    Ulak, G.3    Utkan, T.4    Gacar, N.5
  • 95
    • 33645103130 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects
    • JOCA SR, GUIMARAES FS. Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology (Berl) 2006;185:298-305.
    • (2006) Psychopharmacology (Berl) , vol.185 , pp. 298-305
    • Joca, S.R.1    Guimaraes, F.S.2
  • 96
    • 36249009890 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis
    • ZHOU QG, HU Y, HUA Y et al. Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. J Neurochem 2007;103:1843-1854.
    • (2007) J Neurochem , vol.103 , pp. 1843-1854
    • Zhou, Q.G.1    Hu, Y.2    Hua, Y.3
  • 97
    • 58549101276 scopus 로고    scopus 로고
    • Effects of neuronal and inducible NOS inhibitor 1-[2- (trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice
    • MUTLU O, ULAK G, LAUGERAY A, BELZUNG C. Effects of neuronal and inducible NOS inhibitor 1-[2- (trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice. Pharmacol Biochem Behav 2009;92:82-87.
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 82-87
    • Mutlu, O.1    Ulak, G.2    Laugeray, A.3    Belzung, C.4
  • 98
    • 84882787934 scopus 로고    scopus 로고
    • Inhibition of the L-arginine-nitric oxide pathway mediates the antidepressant effects of ketamine in rats in the forced swimming test
    • ZHANG GF, WANG N, SHI JY et al. Inhibition of the L-arginine-nitric oxide pathway mediates the antidepressant effects of ketamine in rats in the forced swimming test. Pharmacol Biochem Behav 2013;110:8-12.
    • (2013) Pharmacol Biochem Behav , vol.110 , pp. 8-12
    • Zhang, G.F.1    Wang, N.2    Shi, J.Y.3
  • 99
    • 84927177808 scopus 로고    scopus 로고
    • Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression
    • LIEBENBERG N, JOCA S, WEGENER G. Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression. Acta Neuropsychiatr 2015;27:90-96.
    • (2015) Acta Neuropsychiatr , vol.27 , pp. 90-96
    • Liebenberg, N.1    Joca, S.2    Wegener, G.3
  • 100
    • 0029128484 scopus 로고
    • Regulation of glutamate efflux by excitatory amino acid receptors: Evidence for tonic inhibitory and phasic excitatory regulation
    • LIU J, MOGHADDAM B. Regulation of glutamate efflux by excitatory amino acid receptors: evidence for tonic inhibitory and phasic excitatory regulation. J Pharmacol Exp Ther 1995;274:1209-1215.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 1209-1215
    • Liu, J.1    Moghaddam, B.2
  • 101
    • 79959350106 scopus 로고    scopus 로고
    • Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression
    • KOIKE H, IIJIMA M, CHAKI S. Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression. Behav Brain Res 2011;224:107-111.
    • (2011) Behav Brain Res , vol.224 , pp. 107-111
    • Koike, H.1    Iijima, M.2    Chaki, S.3
  • 102
    • 38349186799 scopus 로고    scopus 로고
    • Cellular mechanisms underlying the antidepressant effects of ketamine: Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors
    • MAENG S, ZARATE CA JR., DU J et al. Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biol Psychiatry 2008;63:349-352.
    • (2008) Biol Psychiatry , vol.63 , pp. 349-352
    • Maeng, S.1    Zarate, C.A.J.R.2    Du, J.3
  • 104
    • 80054106740 scopus 로고    scopus 로고
    • The antidepressantlike effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf (+)/(-) heterozygous null mice
    • LINDHOLM JS, AUTIO H, VESA L et al. The antidepressantlike effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf (+)/(-) heterozygous null mice. Neuropharmacology 2012;62:391-397.
    • (2012) Neuropharmacology , vol.62 , pp. 391-397
    • Lindholm, J.S.1    Autio, H.2    Vesa, L.3
  • 105
    • 80053379549 scopus 로고    scopus 로고
    • Chronic antidepressant treatments induce a time-dependent upregulation of AMPA receptor subunit protein levels
    • BARBON A, CARACCIOLO L, ORLANDI C et al. Chronic antidepressant treatments induce a time-dependent upregulation of AMPA receptor subunit protein levels. Neurochem Int 2011;59:896-905.
    • (2011) Neurochem Int , vol.59 , pp. 896-905
    • Barbon, A.1    Caracciolo, L.2    Orlandi, C.3
  • 106
    • 80054116238 scopus 로고    scopus 로고
    • Towards a glutamate hypothesis of depression: An emerging frontier of neuropsychopharmacology for mood disorders
    • SANACORA G, TRECCANI G, POPOLI M. Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology 2012;62:63-77.
    • (2012) Neuropharmacology , vol.62 , pp. 63-77
    • Sanacora, G.1    Treccani, G.2    Popoli, M.3
  • 107
    • 67650473167 scopus 로고    scopus 로고
    • Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation
    • JOURDI H, HSU YT, ZHOU M, QIN Q, BI X, BAUDRY M. Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation. J Neurosci 2009;29:8688-8697.
    • (2009) J Neurosci , vol.29 , pp. 8688-8697
    • Jourdi, H.1    Hsu, Y.T.2    Zhou, M.3    Qin, Q.4    Bi, X.5    Baudry, M.6
  • 109
    • 84857083262 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex
    • LIU RJ, LEE FS, LI XY, BAMBICO F, DUMAN RS, AGHAJANIAN GK. Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biol Psychiatry 2012; 71:996-1005.
    • (2012) Biol Psychiatry , vol.71 , pp. 996-1005
    • Liu, R.J.1    Lee, F.S.2    Li, X.Y.3    Bambico, F.4    Duman, R.S.5    Aghajanian, G.K.6
  • 110
    • 79955039215 scopus 로고    scopus 로고
    • Chronic ketamine use increases serum levels of brain-derived neurotrophic factor
    • RICCI V, MARTINOTTI G, GELFO F et al. Chronic ketamine use increases serum levels of brain-derived neurotrophic factor. Psychopharmacology (Berl) 2011;215:143-148.
    • (2011) Psychopharmacology (Berl) , vol.215 , pp. 143-148
    • Ricci, V.1    Martinotti, G.2    Gelfo, F.3
  • 111
    • 84886826594 scopus 로고    scopus 로고
    • MTOR complexes in neurodevelopmental and neuropsychiatric disorders
    • COSTA-MATTIOLI M, MONTEGGIA LM. mTOR complexes in neurodevelopmental and neuropsychiatric disorders. Nat Neurosci 2013;16:1537-1543.
    • (2013) Nat Neurosci , vol.16 , pp. 1537-1543
    • Costa-Mattioli, M.1    Monteggia, L.M.2
  • 112
    • 40649119181 scopus 로고    scopus 로고
    • The effect of MK-801 on mTOR/p70S6K and translation-related proteins in rat frontal cortex
    • YOON SC, SEO MS, KIM SH et al. The effect of MK-801 on mTOR/p70S6K and translation-related proteins in rat frontal cortex. Neurosci Lett 2008;434:23-28.
    • (2008) Neurosci Lett , vol.434 , pp. 23-28
    • Yoon, S.C.1    Seo, M.S.2    Kim, S.H.3
  • 113
    • 1642307858 scopus 로고    scopus 로고
    • Regulation of MAPK/ERK phosphorylation via ionotropic glutamate receptors in cultured rat striatal neurons
    • MAO L, TANG Q, SAMDANI S, LIU Z, WANG JQ. Regulation of MAPK/ERK phosphorylation via ionotropic glutamate receptors in cultured rat striatal neurons. Eur J Neurosci 2004;19:1207-1216.
    • (2004) Eur J Neurosci , vol.19 , pp. 1207-1216
    • Mao, L.1    Tang, Q.2    Samdani, S.3    Liu, Z.4    Wang, J.Q.5
  • 114
    • 2542439782 scopus 로고    scopus 로고
    • Glutamate signaling to Ras-MAPK in striatal neurons: Mechanisms for inducible gene expression and plasticity
    • WANG JQ, TANG Q, PARELKAR NK et al. Glutamate signaling to Ras-MAPK in striatal neurons: mechanisms for inducible gene expression and plasticity. Mol Neurobiol 2004; 29:1-14.
    • (2004) Mol Neurobiol , vol.29 , pp. 1-14
    • Wang, J.Q.1    Tang, Q.2    Parelkar, N.K.3
  • 115
    • 79952182383 scopus 로고    scopus 로고
    • Potential therapeutic uses of BDNF in neurological and psychiatric disorders
    • NAGAHARA AH, TUSZYNSKI MH. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov 2011;10:209-219.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 209-219
    • Nagahara, A.H.1    Tuszynski, M.H.2
  • 116
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • GRIMES CA, JOPE RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 2001;65:391-426.
    • (2001) Prog Neurobiol , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 117
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • ZONCU R, EFEYAN A, SABATINI DM. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 2011;12:21-35.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 118
    • 85028117370 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
    • BEUREL E, SONG L, JOPE RS. Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice. Mol Psychiatry 2011;16:1068-1070.
    • (2011) Mol Psychiatry , vol.16 , pp. 1068-1070
    • Beurel, E.1    Song, L.2    Jope, R.S.3
  • 119
    • 84884288609 scopus 로고    scopus 로고
    • GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine
    • LIU RJ, FUCHIKAMI M, DWYER JM, LEPACK AE, DUMAN RS, AGHAJANIAN GK. GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology 2013;38: 2268-2277.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2268-2277
    • Liu, R.J.1    Fuchikami, M.2    Dwyer, J.M.3    Lepack, A.E.4    Duman, R.S.5    Aghajanian, G.K.6
  • 120
    • 84981484055 scopus 로고    scopus 로고
    • The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model of stress
    • pii: pyu102
    • CHIU CT, SCHEUING L, LIU G et al. The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model of stress. Int J Neuropsychopharmacol 2015;18: pii: pyu102.
    • (2015) Int J Neuropsychopharmacol , pp. 18
    • Chiu, C.T.1    Scheuing, L.2    Liu, G.3
  • 121
    • 84923265392 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
    • BEUREL E, GRIECO SF, JOPE RS. Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases. Pharmacol Ther 2015;148:114-131.
    • (2015) Pharmacol Ther , vol.148 , pp. 114-131
    • Beurel, E.1    Grieco, S.F.2    Jope, R.S.3
  • 122
    • 84873510192 scopus 로고    scopus 로고
    • Long-lasting antidepressant action of ketamine, but not glycogen synthase kinase-3 inhibitor SB216763, in the chronic mild stress model of mice
    • MA XC, DANG YH, JIA M et al. Long-lasting antidepressant action of ketamine, but not glycogen synthase kinase-3 inhibitor SB216763, in the chronic mild stress model of mice. PLoS One 2013;8:e56053.
    • (2013) PLoS One , vol.8
    • Ma, X.C.1    Dang, Y.H.2    Jia, M.3
  • 123
    • 84998013997 scopus 로고    scopus 로고
    • Ketamine as the prototype glutamatergic antidepressant: Pharmacodynamic actions, and a systematic review and meta-analysis of efficacy
    • CADDY C, GIAROLI G, WHITE TP, SHERGILL SS, TRACY DK. Ketamine as the prototype glutamatergic antidepressant: pharmacodynamic actions, and a systematic review and meta-analysis of efficacy. Ther Adv Psychopharmacol 2014;4:75-99.
    • (2014) Ther Adv Psychopharmacol , vol.4 , pp. 75-99
    • Caddy, C.1    Giaroli, G.2    White, T.P.3    Shergill, S.S.4    Tracy, D.K.5
  • 124
    • 85017591670 scopus 로고    scopus 로고
    • A consensus statement on the use of ketamine in the treatment of mood disorders
    • SANACORA G, FRYE MA, MCDONALD W et al. A consensus statement on the use of ketamine in the treatment of mood disorders. JAMA Psychiatry 2017;74:399-405.
    • (2017) JAMA Psychiatry , vol.74 , pp. 399-405
    • Sanacora, G.1    Frye, M.A.2    McDonald, W.3
  • 125
    • 84991030713 scopus 로고    scopus 로고
    • Balancing the promise and risks of ketamine treatment for mood disorders
    • SANACORA G, HEIMER H, HARTMAN D et al. Balancing the promise and risks of ketamine treatment for mood disorders. Neuropsychopharmacology 2017;42:1179-1181.
    • (2017) Neuropsychopharmacology , vol.42 , pp. 1179-1181
    • Sanacora, G.1    Heimer, H.2    Hartman, D.3
  • 126
    • 85028935269 scopus 로고    scopus 로고
    • Considerations on the off-label use of ketamine as a treatment for mood disorders
    • WILKINSON ST, SANACORA G. Considerations on the off-label use of ketamine as a treatment for mood disorders. JAMA 2017;318:793-794.
    • (2017) JAMA , vol.318 , pp. 793-794
    • Wilkinson, S.T.1    Sanacora, G.2
  • 127
    • 84926305080 scopus 로고    scopus 로고
    • NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDAGluN2B antagonism
    • KISELYCZNYK C, JURY NJ, HALLADAY LR et al. NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDAGluN2B antagonism. Behav Brain Res 2015;287:89-95.
    • (2015) Behav Brain Res , vol.287 , pp. 89-95
    • Kiselycznyk, C.1    Jury, N.J.2    Halladay, L.R.3
  • 128
    • 84878356520 scopus 로고    scopus 로고
    • Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain
    • LIMA-OJEDA JM, VOGT MA, PFEIFFER N et al. Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain. Prog Neuropsychopharmacol Biol Psychiatry 2013;45:28-33.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.45 , pp. 28-33
    • Lima-Ojeda, J.M.1    Vogt, M.A.2    Pfeiffer, N.3
  • 129
    • 59049098262 scopus 로고    scopus 로고
    • An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder
    • PRESKORN SH, BAKER B, KOLLURI S, MENNITI FS, KRAMS M, LANDEN JW. An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. J Clin Psychopharmacol 2008;28: 631-637.
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 631-637
    • Preskorn, S.H.1    Baker, B.2    Kolluri, S.3    Menniti, F.S.4    Krams, M.5    Landen, J.W.6
  • 130
    • 84959359722 scopus 로고    scopus 로고
    • Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice
    • POLESZAK E, STASIUK W, SZOPA A et al. Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Metab Brain Dis 2016;31:803-814.
    • (2016) Metab Brain Dis , vol.31 , pp. 803-814
    • Poleszak, E.1    Stasiuk, W.2    Szopa, A.3
  • 131
    • 85012260196 scopus 로고    scopus 로고
    • Ketamine and beyond: Investigations into the potential of glutamatergic agents to treat depression
    • LENER MS, KADRIU B, ZARATE CA JR. Ketamine and beyond: investigations into the potential of glutamatergic agents to treat depression. Drugs 2017;77:381-401.
    • (2017) Drugs , vol.77 , pp. 381-401
    • Lener, M.S.1    Kadriu, B.2    Zarate, C.A.J.R.3
  • 132
    • 84863719297 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder
    • IBRAHIM L, DIAZ GRANADOS N, JOLKOVSKY L et al. A randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder. J Clin Psychopharmacol 2012;32:551-557.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 551-557
    • Ibrahim, L.1    Diaz Granados, N.2    Jolkovsky, L.3
  • 133
    • 84949599459 scopus 로고    scopus 로고
    • Negative allosteric modulators selective for the NR2B subtype of the NMDA receptor impair cognition in multiple domains
    • WEED MR, BOOKBINDER M, POLINO J et al. Negative allosteric modulators selective for the NR2B subtype of the NMDA receptor impair cognition in multiple domains. Neuropsychopharmacology 2016;41:568-577.
    • (2016) Neuropsychopharmacology , vol.41 , pp. 568-577
    • Weed, M.R.1    Bookbinder, M.2    Polino, J.3
  • 135
    • 84878254691 scopus 로고    scopus 로고
    • NMDA receptor subunit diversity: Impact on receptor properties, synaptic plasticity and disease
    • PAOLETTI P, BELLONE C, ZHOU Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci 2013;14:383-400.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 383-400
    • Paoletti, P.1    Bellone, C.2    Zhou, Q.3
  • 136
    • 84949008313 scopus 로고    scopus 로고
    • GLYX-13 (rapastinel) ameliorates subchronic phencyclidine-and ketamine-induced declarative memory deficits in mice
    • RAJAGOPAL L, BURGDORF JS, MOSKAL JR, MELTZER HY. GLYX-13 (rapastinel) ameliorates subchronic phencyclidine-and ketamine-induced declarative memory deficits in mice. Behav Brain Res 2016;299:105-110.
    • (2016) Behav Brain Res , vol.299 , pp. 105-110
    • Rajagopal, L.1    Burgdorf, J.S.2    Moskal, J.R.3    Meltzer, H.Y.4
  • 137
    • 79953060836 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats
    • BURGDORF J, ZHANG XL, WEISS C et al. The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiol Aging 2011;32:698-706.
    • (2011) Neurobiol Aging , vol.32 , pp. 698-706
    • Burgdorf, J.1    Zhang, X.L.2    Weiss, C.3
  • 138
    • 84875222862 scopus 로고    scopus 로고
    • GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects
    • BURGDORF J, ZHANG XL, NICHOLSON KL et al. GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects. Neuropsychopharmacology 2013;38:729-742.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 729-742
    • Burgdorf, J.1    Zhang, X.L.2    Nicholson, K.L.3
  • 139
    • 85017398233 scopus 로고    scopus 로고
    • NMDA receptor glycine site modulators as therapeutics for depression: Rapastinel has antidepressant activity without causing psychotomimetic side effects
    • BURCH RM, AMIN KHAN M, HOUCK D et al. NMDA receptor glycine site modulators as therapeutics for depression: rapastinel has antidepressant activity without causing psychotomimetic side effects. Curr Neuropharmacol 2016, doi: 10.2174/1570159X14666160202121319.
    • (2016) Curr Neuropharmacol
    • Burch, R.M.1    Amin Khan, M.2    Houck, D.3
  • 140
    • 84942740187 scopus 로고    scopus 로고
    • The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus
    • BURGDORF J, ZHANG XL, WEISS C et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience 2015; 308:202-211.
    • (2015) Neuroscience , vol.308 , pp. 202-211
    • Burgdorf, J.1    Zhang, X.L.2    Weiss, C.3
  • 141
    • 84931263071 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR signalingmediated neuropeptide VGF in the hippocampus of mice is involved in the rapid onset antidepressant-like effects of GLYX-13
    • pii: pyu110
    • LU Y, WANG C, XUE Z et al. PI3K/AKT/mTOR signalingmediated neuropeptide VGF in the hippocampus of mice is involved in the rapid onset antidepressant-like effects of GLYX-13. Int J Neuropsychopharmacol 2015;18: pii: pyu110.
    • (2015) Int J Neuropsychopharmacol , pp. 18
    • Lu, Y.1    Wang, C.2    Xue, Z.3
  • 142
    • 85010640119 scopus 로고    scopus 로고
    • The development of rapastinel (formerly GLYX-13); A rapid acting and long lasting antidepressant
    • MOSKAL JR, BURGDORF JS, STANTON PK et al. The development of rapastinel (formerly GLYX-13); a rapid acting and long lasting antidepressant. Curr Neuropharmacol 2017;15:47-56.
    • (2017) Curr Neuropharmacol , vol.15 , pp. 47-56
    • Moskal, J.R.1    Burgdorf, J.S.2    Stanton, P.K.3
  • 144
    • 84929617020 scopus 로고    scopus 로고
    • Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent
    • PRESKORN S, MACALUSO M, MEHRA DO et al. Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent. J Psychiatr Pract 2015;21:140-149.
    • (2015) J Psychiatr Pract , vol.21 , pp. 140-149
    • Preskorn, S.1    MacAluso, M.2    Mehra, D.O.3
  • 146
    • 0023007932 scopus 로고
    • Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine
    • LEUNG LY, BAILLIE TA. Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine. J Med Chem 1986;29:2396-2399.
    • (1986) J Med Chem , vol.29 , pp. 2396-2399
    • Leung, L.Y.1    Baillie, T.A.2
  • 147
    • 84939794820 scopus 로고    scopus 로고
    • Antidepressant-like effects of ketamine, norketamine and dehydronorketamine in forced swim test: Role of activity at NMDA receptor
    • SALAT K, SIWEK A, STAROWICZ G et al. Antidepressant-like effects of ketamine, norketamine and dehydronorketamine in forced swim test: role of activity at NMDA receptor. Neuropharmacology 2015;99:301-307.
    • (2015) Neuropharmacology , vol.99 , pp. 301-307
    • Salat, K.1    Siwek, A.2    Starowicz, G.3
  • 148
    • 84863734573 scopus 로고    scopus 로고
    • Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression
    • ZHAO X, VENKATA SL, MOADDEL R et al. Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression. Br J Clin Pharmacol 2012;74:304-314.
    • (2012) Br J Clin Pharmacol , vol.74 , pp. 304-314
    • Zhao, X.1    Venkata, S.L.2    Moaddel, R.3
  • 149
    • 84969672767 scopus 로고    scopus 로고
    • NMDAR inhibition-independent antidepressant actions of ketamine metabolites
    • ZANOS P, MOADDEL R, MORRIS PJ et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature 2016;533:481-486.
    • (2016) Nature , vol.533 , pp. 481-486
    • Zanos, P.1    Moaddel, R.2    Morris, P.J.3
  • 150
    • 77957231941 scopus 로고    scopus 로고
    • Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm
    • FARLEY S, APAZOGLOU K, WITKIN JM, GIROS B, TZAVARA ET. Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm. Int J Neuropsychopharmacol 2010;13:1207-1218.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 1207-1218
    • Farley, S.1    Apazoglou, K.2    Witkin, J.M.3    Giros, B.4    Tzavara, E.T.5
  • 151
    • 84865858577 scopus 로고    scopus 로고
    • Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: A summary and method analysis of bridging research in support of phase II dose selection
    • NATIONS KR, BURSI R, DOGTEROM P et al. Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection. Drugs R D 2012;12:127-139.
    • (2012) Drugs R D , vol.12 , pp. 127-139
    • Nations, K.R.1    Bursi, R.2    Dogterom, P.3
  • 152
    • 84870427621 scopus 로고    scopus 로고
    • Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: An exploratory, randomized, double-blind, placebo-controlled trial
    • NATIONS KR, DOGTEROM P, BURSI R et al. Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial. J Psychopharmacol 2012;26: 1525-1539.
    • (2012) J Psychopharmacol , vol.26 , pp. 1525-1539
    • Nations, K.R.1    Dogterom, P.2    Bursi, R.3
  • 153
    • 84916618771 scopus 로고    scopus 로고
    • Ketamine and other potential glutamate antidepressants
    • DUTTA A, MCKIE S, DEAKIN JF. Ketamine and other potential glutamate antidepressants. Psychiatry Res 2015;225:1-13.
    • (2015) Psychiatry Res , vol.225 , pp. 1-13
    • Dutta, A.1    McKie, S.2    Deakin, J.F.3
  • 154
    • 84941173456 scopus 로고    scopus 로고
    • Antidepressant drug action - From rapid changes on network function to network rewiring
    • RANTAMAKI T, YALCIN I. Antidepressant drug action - from rapid changes on network function to network rewiring. Prog Neuropsychopharmacol Biol Psychiatry 2016;64:285-292.
    • (2016) Prog Neuropsychopharmacol Biol Psychiatry , vol.64 , pp. 285-292
    • Rantamaki, T.1    Yalcin, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.