Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: Implications for the pharmacotherapy of depression

Pharmacopsychiatry

Volumn 29, Issue 1, 1996, Pages 23-26

  Skolnick, P ^a,e   Layer, R T ^a   Popik, P ^b   Nowak, G ^b,c   Paul, I A ^c   Trullas, R ^d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

^c UNIVERSITY OF MISSISSIPPI   (United States)

^d CSIC   (Spain)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID; 2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; ANTIDEPRESSANT AGENT; BETA ADRENERGIC RECEPTOR; CITALOPRAM; IMIPRAMINE; ION CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DEPRESSION; DRUG RECEPTOR BINDING; ELECTRIC SHOCK; FRONTAL CORTEX; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0030032399     PISSN: 01763679     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979537     Document Type: Article

References (28)

1. Banerjee, S. P., L. S. Kung, S. J. Riggi, S. K. Chanda: Development of beta adrenergic receptor subsensitivity by antidepressants. Nature 268 (1977) 455-456
2. Cherkofsky, S. C.: 1-Aminocyclopropanecarboxylic acid: mouse to man interspecies pharmacokinetic comparisons and allometric relationships. J. Pharmaceut. Sci. 84 (1995) 1231-1235
3. Heninger, G., D. Charney: Mechanism of action of antidepressant treatments: implications for the etiology and treatment of depressived disorders. In: Meltzer, H. (ed.) Psychopharmacology: The third generation of progress, Raven Press, N.Y. (1987) Chapter 54, pp. 535-544
4. 2 receptors in the chronic mild stress model of depression in rats. Pol. J. Pharmacol. 46 (1994) 67-69
5. Krystal, J. H., L. P. Karper, J. P. Seibyl, G. K. Freeman, R. Delaney, J. D. Bremmer, G. R. Heninger, M. B. Bowers, D. S. Charney: Subanesthetic doses of the noncompetitive NMDA antagonist, ketamine in humans: Psychotomimetic, perceptual, cognitive and neuroendocrine responses. Arch. Gen. Psychiatry 51 (1994) 199-214
6. Layer, R. T., P. Popik, G. Nowak, I. A. Paul, R. Trullas, P. Skolnick: A unified theory of antidepressant action: evidence for adaptation of the N-methyl-D-aspartate (NMDA) receptor following chronic antidepressant treatments. In: Ceña, V., B. Soria (eds.) Ion Channel Pharmacology, Oxford University Press, London (1995a) in press
7. Layer, R. T., P. Popik, T. Olds, P. Skolnick: Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL 82.0715). Pharmacol. Biochem. Behav. 52 (1995) 615-620
8. Maj, J., Z. Rogóz, G. Skuza, H. Sowinska: The effect of CGP 37849 and CGP 39551, competitive NMDA receptor antagonists, in the forced swimming test. Pol. J. Pharmacol. 44 (1992) 337-346
9. Moghaddam, B.: Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to the hippocampus and basal ganglia. J. Neurchem. 60 (1993) 1650-1657
10. Moryl, E., W. Danysz, G. Quack: Potential antidepressive of amantadine, memantine and bifemelane. Pharmacol. & Toxicol. 72 (1993) 394-397
11. Muir, K. W., D. G. Grosset, E. Gamzu, K. R. Lees: Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers. Brit. J. Clin. Pharmac. 38 (1994) 33-38
12. Muscat, R., M. Papp, P. Willner: Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline. Psychopharmacol. 109 (1992) 433-438
13. Nowak, G., R. Trullas, R. T. Layer, P. Skolnick, I. A. Paul: Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocydopropanecarboxylic acid. J. Pharmacol. Exp. Ther. 265 (1993) 1380-1386
14. Nowak, G., G. A. Ordway, I. A. Paul: Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res. 675 (1995a) 157-164
15. Nowak, G., Y. Li, I. A. Paul: Adaptation of cortical but not hippocampal glutamate-NDMA receptors after chronic citalopram treatment. Eur. J. Pharmacol. (1995b) in press
16. Panconi, E., J. Roux, M. Altenbaumer, S. Hampe, R. D. Porsolt: MK-801 and enantiomers: potential antidepressants or false positives in classical screening models? Pharmacol. Biochem. Behav. 46 (1993) 15-20
17. Papp, M., E. Moryl: Similar effects of chronic treatment with imipramine and the NMDA antagonists CGP 37849 and MK-801 in a chronic mild stress model of depression in rats. Eur. J. Neuropsychopharmacol. 3 (1993) 348-349
18. Papp, M., E. Moryl: Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression. Eur. J. Pharmacol. 263 (1994) 1-7
19. Patat, A., P. Molinier, T. Hergueta, S. Brohier, I. Zieleniuk, P. Danjou, D. Warot, A. Puech: Lack of amnestic, psychotomimetic or impairing effect on psychomotor performance of eliprodil, a new NMDA antagonist. Int. Clin. Psychopharm. 9 (1994) 155-162
20. Paul, I. A., R. T. Layer, P. Skolnick, G. Nowak: Adaption of the N-Methyl-D-Aspartate receptor complex in rat front cortex following chronic treatment with electroconvulsive shock or imipramine. Eur. J. Pharmacol. 247 (1993) 305-312
21. Paul, I. A., G. Nowak, R. T. Layer, P. Popik, P. Skolnick: Adaptation of the N-Methyl-D-Aspartate receptor complex following chronic antidepressant treatments. J. Pharmacol. Exp. Ther. 269 (1994) 95-102
22. Paul, I. A., R. Trullas, P. Skolnick, G. Nowak: Down-regulation of cortical β-adrenoceptors by chronic treatment with functional NMDA antagonists. Psychopharmacol. 106 (1992) 285-287
23. Porsolt, R. D.: Behavioral despair. In: S. J. Enna, J. B. Malik, E. Richelson (eds.): Antidepressants: neurochemical, behavioral and clinical perspectives. Raven Press, N. Y. (1981) 121-139
24. Porsolt, R. D., A. Bertin, M. Jalfre: Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 229 (1977) 327-336
25. Steru, L., R. Chermat, B. Theirry, J. A. Mico, A. Lenegre, M. Steru, P. Simon, R. D. Porsolt: The automated tail suspension test: a computerized device which differentiates psychotropic drugs. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 11 (1987) 659
26. Sveinbjornsdottir, S., J. W. A. S. Sander, D. Upton, P. J. Thompson, P. N. Patsalos, D. Hirt, M. Emre, D. Lowe, J. S. Duncan: The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy. Epilepsy Res. 16 (1993) 165-174
27. Trullas, R., P. Skolnick: Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur. J. Pharmacol. 185 (1990) 1-10
28. Willner, P., R. Muscat, M. Papp: Chronic mild stress-induced anhedonia: a realistic animal model of depression. Neurosci. & Biobehav. Rev. 16 (1992) 525-534