Drug repurposing: Progress, challenges and recommendations

Nature Reviews Drug Discovery

Volumn 18, Issue 1, 2018, Pages 41-58

  Pushpakom, Sudeep ^a   Iorio, Francesco ^b   Eyers, Patrick A ^a   Escott, K Jane ^c   Hopper, Shirley ^d   Wells, Andrew ^e   Doig, Andrew ^f   Guilliams, Tim ^g   Latimer, Joanna ^h   McNamee, Christine ^a   Norris, Alan ^a   Sanseau, Philippe ⁱ   Cavalla, David ^j   Pirmohamed, Munir ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

^d MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY   (United Kingdom)

^e Patent and Trademark Attorneys   (United Kingdom)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

^g Healx Ltd   (United Kingdom)

^h MEDICAL RESEARCH COUNCIL   (United Kingdom)

ⁱ GLAXOSMITHKLINE   (United Kingdom)

^j Numedicus Ltd   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CEFTRIAXONE; DENOSUMAB; DIMEBON; ERTEBEREL; FASUDIL; NELFINAVIR; NEUROKININ 3 RECEPTOR ANTAGONIST; PAVINETANT; RIBAVIRIN; SARACATINIB; TOPIRAMATE; ZIBOTENTAN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; BINDING ASSAY; BONE PAIN; CROHN DISEASE; DRUG COST; DRUG INDUSTRY; DRUG LEGISLATION; DRUG MARKETING; DRUG REPOSITIONING; DRUG RESEARCH; ELECTRONIC HEALTH RECORD; EUROPEAN UNION; GENE REGULATORY NETWORK; HOT FLUSH; HUMAN; INFLAMMATORY BOWEL DISEASE; LYMPHANGIOLEIOMYOMATOSIS; MOLECULAR DOCKING; NEXT GENERATION SEQUENCING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RARE DISEASE; REVIEW; RISK ASSESSMENT; TREATMENT FAILURE; UNITED STATES; DRUG DEVELOPMENT;

DRUG DISCOVERY; DRUG INDUSTRY; DRUG REPOSITIONING; HUMANS;

EID: 85057067854     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd.2018.168     Document Type: Review

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