Activation of neurokinin 3 receptors in the median preoptic nucleus decreases core temperature in the rat

Endocrinology

Volumn 152, Issue 12, 2011, Pages 4894-4905

  Dacks, Penny A ^a   Krajewski, Sally J ^a   Rance, Naomi E ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; ESTRADIOL; NEUROKININ 3 RECEPTOR; NEUROKININ B; PROTEIN FOS; SENKTIDE;

ADRENERGIC SYSTEM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; CORE TEMPERATURE; DOSE RESPONSE; DRINKING BEHAVIOR; DRUG EFFECT; DRUG INFUSION; EATING; ENVIRONMENTAL TEMPERATURE; FEMALE; FLUORESCENCE; FOREBRAIN; GROOMING; HEAT LOSS; HISTOPATHOLOGY; HORMONE SUBSTITUTION; HOT FLUSH; HYPERTHERMIA; HYPOTHERMIA; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INJECTION SITE; LOCOMOTION; MICROINFUSION; MOUSE; NERVE CELL; NONHUMAN; OVARIECTOMY; PREOPTIC NUCLEUS; PRIORITY JOURNAL; REARING; SIGNAL TRANSDUCTION; TAIL; THERMOGENESIS; THERMOREGULATION; VASOCONSTRICTION;

ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; ESTRADIOL; FEMALE; HOT FLASHES; NEUROKININ B; NEURONS; PEPTIDE FRAGMENTS; PREOPTIC AREA; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RECEPTORS, NEUROKININ-3; SUBSTANCE P;

EID: 82355165076     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1492     Document Type: Article

References (65)

1. Stearns V, Ullmer L, López JF, Smith Y, Isaacs C, Hayes DF 2002 Hot flushes. Lancet 360:1851-1861 (Pubitemid 35449427)
2. Santoro N 2008 Symptoms of menopause: hot flushes. Clin Obstet Gynecol 51:539-548
3. Casper RF, Yen SSC 1985 Neuroendocrinology of menopausal flushes: an hypothesis of flush mechanism. Clin Endocrinol 22:293-312 (Pubitemid 15127299)
4. Freedman RR 2001 Physiology of hot flashes. Am J Human Biol 13:453-464 (Pubitemid 32590928)
5. Casper RF, Yen SS, Wilkes MM 1979 Menopausal flushes: a neuroendocrine link with pulsatile luteinizing hormone secretion. Science 205:823-825 (Pubitemid 10245928)
6. Tataryn IV, Meldrum DR, Lu KH, Frumar AM, Judd HL 1979 LH, FSH and skin temperature during the menopausal hot flash. J Clin Endocrinol Metab 49:152-154 (Pubitemid 9211981)
7. Gambone J, Meldrum DR, Laufer L, Chang RJ, Lu JK, Judd HL 1984 Further delineation of hypothalamic dysfunction responsible for menopausal hot flashes. J Clin Endocrinol Metab 59:1097-1102 (Pubitemid 15223343)
8. Rance NE, Young 3rd WS 1991 Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women. Endocrinology 128:2239-2247
9. Rometo AM, Krajewski SJ, Voytko ML, Rance NE 2007 Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys. J Clin Endocrinol Metab 92:2744-2750 (Pubitemid 47037385)
10. Rance NE, Bruce TR 1994 Neurokinin B gene expression is increased in the arcuate nucleus of ovariectomized rats. Neuroendocrinology 60:337-345 (Pubitemid 24284817)
11. Abel TW, Voytko ML, Rance NE 1999 The effects of hormone replacement therapy on hypothalamic neuropeptide gene expression in a primate model of menopause. J Clin Endocrinol Metab 84:2111-2118 (Pubitemid 30647042)
12. Pillon D, Caraty A, Fabre-Nys C, Bruneau G 2003 Short-term effect of oestradiol on neurokinin B mRNA expression in the infundibular nucleus of ewes. J Neuroendocrinol 15:749-753 (Pubitemid 36874371)
13. Sandoval-Guzmán T, Stalcup ST, Krajewski SJ, Voytko ML, Rance NE 2004 Effects of ovariectomy on the neuroendocrine axes regulating reproduction and energy balance in young cynomolgus macaques. J Neuroendocrinol 16:146-153 (Pubitemid 38256461)
14. Dellovade TL, Merchenthaler I 2004 Estrogen regulation of neurokinin B gene expression in the mouse arcuate nucleus is mediated by estrogen receptor α. Endocrinology 145:736-742 (Pubitemid 38183816)
15. Topaloglu AK, Reimann F, Guclu M, Yalin AS, Kotan LD, Porter KM, Serin A, Mungan NO, Cook JR, Ozbek MN, Imamoglu S, Akalin NS, Yuksel B, O'Rahilly S, Semple RK 2009 TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. Nat Genet 41:354-358
16. Young J, Bouligand J, Francou B, Raffin-Sanson ML, Gaillez S, Jeanpierre M, Grynberg M, Kamenicky P, Chanson P, Brailly-Tabard S, Guiochon-Mantel A 2010 TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans. J Clin Endocrinol Metab 95:2287-2295
17. Gianetti E, Tusset C, Noel SD, Au MG, Dwyer AA, Hughes VA, Abreu AP, Carroll J, Trarbach E, Silveira LF, Costa EM, de Mendonça BB, de Castro M, Lofrano A, Hall JE, Bolu E, Ozata M, Quinton R, Amory JK, Stewart SE, Arlt W, Cole TR, Crowley WF, Kaiser UB, Latronico AC, Seminara SB 2010 TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood. J Clin Endocrinol Metab 95:2857-2867
18. Rance NE 2009 Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback. Peptides 30:111-122
19. Lehman MN, Coolen LM, Goodman RL 2010 Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arucate nucleus: a central node in the control of gonadotropin-releasing hormone secretion. Endocrinology 151:3479-3489
20. Rance NE, Krajewski SJ, Smith MA, Cholanian M, Dacks PA 2010 Neurokinin B and the hypothalamic regulation of reproduction. Brain Res 1364:116-128
21. Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, Navarro VM, Clifton DK, Mori Y, Tsukamura H, Maeda K, Steiner RA, Okamura H 2010 Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. J Neurosci 30:3124-3132
22. Dacks PA, Krajewski SJ, Rance NE 2011 Ambient temperature and 17β-estradiol modify fos immunoreactivity in the median preoptic nucleus, a putative regulator of skin vasomotion. Endocrinology 152:2750-2759
23. Krajewski SJ, Burke MC, Anderson MJ, McMullen NT, Rance NE 2010 Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat. Neuroscience 166:680-697
24. Shughrue PJ, Lane MV, Merchenthaler I 1996 In situ hybridization analysis of the distribution of neurokinin-3m RNA in the rat central nervous system. J Comp Neurol 372:395-414 (Pubitemid 26277010)
25. Nakamura K, Morrison SF 2010 A thermosensory pathway mediating heat-defense responses. Proc Natl Acad Sci USA 107:8848-8853
26. Laufer R, Gilon C, Chorev M, Selinger Z 1986 Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand. J Biol Chem 261:10257-10263 (Pubitemid 17221960)
27. Wormser U, Laufer R, Hart Y, Chorev M, Gilon C, Selinger Z 1986 Highly selective agonists for substance P receptor subtypes. EMBO J 5:2805-2808
28. Dam TV, Escher E, Quirion R 1990 Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide. Brain Res 506:175-179 (Pubitemid 20020094)
29. Sandoval-Guzmán T, Rance NE 2004 Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamus. Brain Res 1026:307-312 (Pubitemid 39361561)
30. Navarro VM, Gottsch ML, Chavkin C, Okamura H, Clifton DK, Steiner RA 2009 Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/ neurokinin B neurons in the arcuate nucleus of the mouse. J Neurosci 29:11859-11866
31. Billings HJ, Connors JM, Altman SN, Hileman SM, Holaskova I, Lehman MN, McManus CJ, Nestor CC, Jacobs BH, Goodman RL 2010 Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheep. Endocrinology 151:3836-3846
32. Ramaswamy S, Seminara SB, Ali B, Ciofi P, Amin NA, Plant TM 2010 Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus. Endocrinology 151:4494-4503
33. Navarro VM, Castellano JM, McConkey SM, Pineda R, Ruiz-Pino F, Pinilla L, Clifton DK, Tena-Sempere M, Steiner RA 2011 Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat. Am J Physiol Endocrinol Metab 300:E202-E210
34. Opas EE, Rutledge SJ, Vogel RL, Rodan GA, Schmidt A 2004 Rat tail skin temperature regulation by estrogen, phytoestrogens and tamoxifen. Maturitas 48:463-471 (Pubitemid 38993262)
35. Williams H, Dacks PA, Rance NE 2010 An improved method for recording tail skin temperature in the rat reveals changes during the estrous cycle and effects of ovarian steroids. Endocrinology 151:5389-5394
36. Romanovsky AA, Ivanov AI, Shimansky YP 2002 Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J Appl Physiol 92:2667-2679 (Pubitemid 34666399)
37. Watson Jr RE, Wiegand SJ, Clough RW, Hoffman GE 1986 Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7:155-159 (Pubitemid 16082879)
38. Elmquist JK, Ahima RS, Elias CF, Flier JS, Saper CB 1998 Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc Natl Acad Sci USA 95:741-746 (Pubitemid 28083814)
39. Patronas P, Horowitz M, Simon E, Gerstberger R 1998 Differential stimulation of c-fos expression in hypothalamic nuclei of the rat brain during short-term heat acclimation and mild dehydration. Brain Res 798:127-139 (Pubitemid 28342028)
40. Griffond B, Ciofi P, Bayer L, Jacquemard C, Fellmann D 1997 Immunocytochemical detection of the neurokinin B receptor (NK3) on melanin-concentrating hormone (MCH) neurons in rat brain. J Chem Neuroanat 12:183-189 (Pubitemid 27186999)
41. Krajewski SJ, Anderson MJ, Iles-Shih L, Chen KJ, Urbanski HF, Rance NE 2005 Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J Comp Neurol 489:372-386 (Pubitemid 41026235)
42. Paxinos G, Watson C 2007 The rat brain in stereotaxic coordinates. Burlington, MA: Elsevier, Inc
43. Hoffman GE, Smith MS, Fitzsimmons MD 1992 Detecting steroidal effects on immediate early gene expression in the hypothalamus. Neuroprotocols 1:52-66
44. Hoffman GE, Le WW, Sita LV 2008 The importance of titrating antibodies for immunohistochemical methods. Curr Protoc Neurosci Suppl 45:2.12.1-2.12.26
45. Jiao Y, Sun Z, Lee T, Fusco FR, Kimble TD, Meade CA, Cuthbertson S, Reiner A 1999 A simple and sensitive antigen retrieval method for free-floating and slide-mounted tissue sections. J Neurosci Methods 93:149-162
46. Yoshida K, Li X, Cano G, Lazarus M, Saper CB 2009 Parallel preoptic pathways for thermoregulation. J Neurosci 29:11954-11964
47. Dacks PA, Rance NE 2010 Effects of estradiol on the thermoneutral zone and core temperature in ovariectomized rats. Endocrinology 151:1187-1193
48. Stoessl AJ, Dourish CT, Iversen SD 1988 The NK-3 tachykinin receptor agonist senktide elicits 5-HT-mediated behaviour following central or peripheral administration in mice and rats. Br J Pharmacol 94:285-287
49. Nordquist RE, Ballard TM, Algeyer B, Pauly-Evers M, Ozmen L, Spooren W 2010 Pharmacological characterization of senktide-induced tail whips. Neuropharmacology 58:259-267
50. MacKenzie MA 1997 Pathophysiology and clinical implications of human poikilothermia. Ann NY Acad Sci 813:738-740
51. Oerther S 2000 Temperature set-point changes induced by DA D2/3 and 5-HT1A receptor agonists in the rat. Neuroreport 11:3949-3951 (Pubitemid 32038782)
52. Gordon CJ 2005 Temperature and toxicolgy: an integrative, comparative, and environmental approach. Boca Raton, FL: CRC Press
53. Gordon CJ 1990 Thermal biology of the laboratory rat. Physiol Behav 47:963-991 (Pubitemid 20171701)
54. Nagashima K, Nakai S, Tanaka M, Kanosue K 2000 Neuronal circuitries involved in thermoregulation. Auton Neurosci 85:18-25
55. Tanaka M, Ootsuka Y, McKinley MJ, McAllen RM 2007 Independent vasomotor control of rat tail and proximal hairy skin. J Physiol 582:421-433 (Pubitemid 46993585)
56. Morrison SF, Nakamura K, Madden CJ 2008 Central control of thermogenesis in mammals. Exp Physiol 93:773-797 (Pubitemid 351904256)
57. Kiyatkin EA, Brown PL 2005 Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats. Physiol Behav 84:563-570 (Pubitemid 40487475)
58. Owens NC, Ootsuka Y, Kanosue K, McAllen RM 2002 Thermoregulatory control of sympathetic fibres supplying the rat's tail. J Physiol 543:849-858
59. de Menezes RC, Ootsuka Y, Blessing WW 2009 Sympathetic cutaneous vasomotor alerting responses (SCVARs) are associated with hippocampal theta rhythm in non-moving conscious rats. Brain Res 1298:123-130
60. O'Leary DS, Johnson JM, Taylor WF 1985 Mode of neural control mediating rat tail vasodilation during heating. J Appl Physiol 59:1533-1538 (Pubitemid 16197420)
61. Yoshida K, Konishi M, Nagashima K, Saper CB, Kanosue K 2005 Fos activation in hypothalamic neurons during cold or warm exposure: projections to periaqueductal gray matter. Neuroscience 133:1039-1046 (Pubitemid 40814611)
62. Romanovsky AA, Almeida MC, Garami A, Steiner AA, Norman MH, Morrison SF, Nakamura K, Burmeister JJ, Nucci TB 2009 The transient receptor potential vanilloid-1 channel in thermoregulation: a thermosensor it is not. Pharmacol Rev 61:228-261
63. Boulant JA 2000 Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin Infect Dis 31:S157-S161 (Pubitemid 32291105)
64. Srividya R, Mallick HN, Kumar VM 2005 Changes in brain temperature and thermoregulation produced by destruction of medial septal neurons in rats. Brain Res Bull 66:143-148 (Pubitemid 40854087)
65. Romanovsky AA, Sugimoto N, Simons CT, Hunter WS 2003 The organum vasculosum laminae terminalis in immune-to-brain febrigenic signaling: a reappraisal of lesion experiments. Am J Physiol Regul Integr Comp Physiol 285:R420-R428 (Pubitemid 36903241)