Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580

FEBS Letters

Volumn 451, Issue 2, 1999, Pages 191-196

  Eyers, Patrick A ^a   Van Den Ijssel, Paul ^a   Quinlan, Roy A ^a   Goedert, Michel ^b   Cohen, Philip ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

CREB; MAPKAP K2; MSK1; p38; SAPK2; SB203580

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SPECIFICITY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; KIDNEY CELL; MUTANT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANISOMYCIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTAGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-RAF; PYRIDINES; ULTRAVIOLET RAYS;

EID: 0032901378     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00552-9     Document Type: Article

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