Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1

Oncotarget

Volumn 7, Issue 34, 2016, Pages 54515-54525

  Troutman, Scott ^a   Moleirinho, Susana ^a   Kota, Smitha ^a   Nettles, Kendall ^a   Fallahi, Mohammad ^a   Johnson, Gary L ^b   Kissil, Joseph L ^a  

^a Scripps Institute   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Crizotinib; FAK; Neurofibromatosis; Nf2; Signal transduction

Indexed keywords

CRIZOTINIB; FOCAL ADHESION KINASE 1; MERLIN; PROTEIN KINASE INHIBITOR; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG POTENCY; DRUG TARGETING; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NEURILEMOMA; NEUROFIBROMATOSIS TYPE 2; NONHUMAN; SCHWANN CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; DRUG SCREENING; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; FOCAL ADHESION KINASE 1; HUMANS; MICE; NEURILEMMOMA; NEUROFIBROMIN 2; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIDINES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84983505503     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10248     Document Type: Article

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