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Volumn 370, Issue 18, 2014, Pages 1702-1711

Darapladib for preventing ischemic events in stable coronary heart disease

(60)  White, Harvey D a   Held, Claes b   Stewart, Ralph a   Tarka, Elizabeth c   Brown, Rebekkah c   Davies, Richard Y c   Budaj, Andrzej e   Harrington, Robert A f   Steg, P Gabriel g,h,j   Ardissino, Diego k   Armstrong, Paul W l   Avezum, Alvaro n   Aylward, Philip E p   Bryce, Alfonso q   Chen, Hong r   Chen, Ming Fong s   Corbalan, Ramon t   Dalby, Anthony J u   Danchin, Nicolas i   De Winter, Robbert J v   more..

g INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DARAPLADIB; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PHOSPHOLIPASE A2; PLACEBO; BENZALDEHYDE DERIVATIVE; OXIME; PHOSPHOLIPASE A2 INHIBITOR;

EID: 84899718423     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1315878     Document Type: Article
Times cited : (475)

References (22)
  • 5
    • 0033867025 scopus 로고    scopus 로고
    • Lysophosphatidylcholine induces apoptotic and non-apoptotic death in vascular smooth muscle cells: In comparison with oxidized LDL
    • Hsieh CC, Yen MH, Liu HW, Lau YT. Lysophosphatidylcholine induces apoptotic and non-apoptotic death in vascular smooth muscle cells: in comparison with oxidized LDL. Atherosclerosis 2000;151:481-91.
    • (2000) Atherosclerosis , vol.151 , pp. 481-491
    • Hsieh, C.C.1    Yen, M.H.2    Liu, H.W.3    Lau, Y.T.4
  • 6
    • 0033104911 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: Use of a novel inhibitor
    • MacPhee CH, Moores KE, Boyd HF, et al. Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor. Biochem J 1999;338:479-87.
    • (1999) Biochem J , vol.338 , pp. 479-487
    • MacPhee, C.H.1    Moores, K.E.2    Boyd, H.F.3
  • 8
    • 0036119155 scopus 로고    scopus 로고
    • Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism
    • DOI 10.1016/S0021-9150(01)00674-8, PII S0021915001006748
    • Takahashi M, Okazaki H, Ogata Y, Takeuchi K, Ikeda U, Shimada K. Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism. Atherosclerosis 2002;161:387-94. (Pubitemid 34219192)
    • (2002) Atherosclerosis , vol.161 , Issue.2 , pp. 387-394
    • Takahashi, M.1    Okazaki, H.2    Ogata, Y.3    Takeuchi, K.4    Ikeda, U.5    Shimada, K.6
  • 9
    • 77951605907 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: Collaborative analysis of 32 prospective studies
    • Thompson A, Gao P, Orfei L, et al. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 2010;375:1536-44.
    • (2010) Lancet , vol.375 , pp. 1536-1544
    • Thompson, A.1    Gao, P.2    Orfei, L.3
  • 11
    • 53549093853 scopus 로고    scopus 로고
    • Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
    • Wilensky RL, Shi Y, Mohler ER III, et al. Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat Med 2008;14:1059-66.
    • (2008) Nat Med , vol.14 , pp. 1059-1066
    • Wilensky, R.L.1    Shi, Y.2    Mohler III, E.R.3
  • 12
    • 84895869898 scopus 로고    scopus 로고
    • Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: A randomized, controlled trial
    • Johnson JL, Shi Y, Snipes R, et al. Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial. PLoS One 2014;9(2):e89034.
    • (2014) PLoS One , vol.9 , Issue.2
    • Johnson, J.L.1    Shi, Y.2    Snipes, R.3
  • 13
    • 54049152760 scopus 로고    scopus 로고
    • Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
    • Serruys PW, García-García HM, Buszman P, et al. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 2008;118:1172-82.
    • (2008) Circulation , vol.118 , pp. 1172-1182
    • Serruys, P.W.1    García-García, H.M.2    Buszman, P.3
  • 14
    • 77955585234 scopus 로고    scopus 로고
    • Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease
    • White H, Held C, Stewart R, et al. Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease. Am Heart J 2010;160:655-61.
    • (2010) Am Heart J , vol.160 , pp. 655-661
    • White, H.1    Held, C.2    Stewart, R.3
  • 15
    • 33748480111 scopus 로고    scopus 로고
    • Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: A science advisory from the American Heart Association Kidney and Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention; and the Quality of Care and Outcomes Research Interdisciplinary Working Group
    • DOI 10.1161/CIRCULATIONAHA.106.177321, PII 0000301720060905000016
    • Brosius FC III, Hostetter TH, Kelepouris E, et al. Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney and Cardiovascular Disease Council, the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention, and the Quality of Care and Outcomes Research Interdisciplinary Working Group: developed in collaboration with the National Kidney Foundation. Circulation 2006;114:1083-7. (Pubitemid 44358886)
    • (2006) Circulation , vol.114 , Issue.10 , pp. 1083-1087
    • Brosius III, F.C.1    Hostetter, T.H.2    Kelepouris, E.3    Mitsnefes, M.M.4    Moe, S.M.5    Moore, M.A.6    Pennathur, S.7    Smith, G.L.8    Wilson, P.W.F.9
  • 17
    • 77956922384 scopus 로고    scopus 로고
    • Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis
    • Bhatt DL, Eagle KA, Ohman EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA 2010;304:1350-7.
    • (2010) JAMA , vol.304 , pp. 1350-1357
    • Bhatt, D.L.1    Eagle, K.A.2    Ohman, E.M.3
  • 18
    • 84869146976 scopus 로고    scopus 로고
    • Women and men with stable coronary artery disease have similar clinical outcomes: Insights from the international prospective CLARIFY registry
    • Steg PG, Greenlaw N, Tardif JC, et al. Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry. Eur Heart J 2012;33:2831-40.
    • (2012) Eur Heart J , vol.33 , pp. 2831-2840
    • Steg, P.G.1    Greenlaw, N.2    Tardif, J.C.3
  • 19
    • 33646685941 scopus 로고    scopus 로고
    • 2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin or atorVastatin evaluation and infection therapy-thrombolysis in myocardial infarction) trial
    • DOI 10.1161/CIRCULATIONAHA.105.612630, PII 0000301720060411000008
    • O'Donoghue M, Morrow DA, Sabatine MS, et al. Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction) trial. Circulation 2006;113:1745-52. (Pubitemid 43958467)
    • (2006) Circulation , vol.113 , Issue.14 , pp. 1745-1752
    • O'Donoghue, M.1    Morrow, D.A.2    Sabatine, M.S.3    Murphy, S.A.4    McCabe, C.H.5    Cannon, C.P.6    Braunwald, E.7
  • 20
    • 84860653236 scopus 로고    scopus 로고
    • Relationship of lipoprotein-associated phospholipase A2 mass and activity with incident vascular events among primary prevention patients allocated to placebo or to statin therapy: An analysis from the JUPITER trial
    • Ridker PM, MacFadyen JG, Wolfert RL, Koenig W. Relationship of lipoprotein-associated phospholipase A2 mass and activity with incident vascular events among primary prevention patients allocated to placebo or to statin therapy: an analysis from the JUPITER trial. Clin Chem 2012;58:877-86.
    • (2012) Clin Chem , vol.58 , pp. 877-886
    • Ridker, P.M.1    MacFadyen, J.G.2    Wolfert, R.L.3    Koenig, W.4
  • 21
    • 77956306449 scopus 로고    scopus 로고
    • 2 activity and mass in relation to vascular disease and nonvascular mortality
    • Heart Protection Study Collaborative Group
    • 2 activity and mass in relation to vascular disease and nonvascular mortality. J Intern Med 2010;268:348-58.
    • (2010) J Intern Med , vol.268 , pp. 348-358
  • 22
    • 84891705653 scopus 로고    scopus 로고
    • Changes in lipoprotein-associated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: Results from the Long-Term Intervention with Pravastatin in Ischemic Disease study
    • White HD, Simes J, Stewart RA, et al. Changes in lipoprotein-associated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: results from the Long-Term Intervention with Pravastatin in Ischemic Disease study. J Am Heart Assoc 2013;2(5):e000360.
    • (2013) J Am Heart Assoc , vol.2 , Issue.5
    • White, H.D.1    Simes, J.2    Stewart, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.