Efficient base editing in methylated regions with a human apobec3a-cas9 fusion

Nature Biotechnology

Volumn 36, Issue 10, 2018, Pages 946-

  Wang, Xiao ^a,b,c   Li, Jianan ^a,b,c   Wang, Ying ^d   Yang, Bei ^a   Wei, Jia ^d   Wu, Jing ^a   Wang, Ruixuan ^a   Huang, Xingxu ^a   Chen, Jia ^a   Yang, Li ^d  

^a SHANGHAITECH UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d Chinese Academy of Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION;

DINUCLEOTIDES; SINGLE NUCLEOTIDES;

NUCLEOTIDES;

APOBEC3A PROTEIN, HUMAN; CYTIDINE DEAMINASE; DNA; PROTEIN;

DNA METHYLATION; GENE EDITING; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; PROCEDURES; SITE DIRECTED MUTAGENESIS;

BASE SEQUENCE; CRISPR-ASSOCIATED PROTEIN 9; CYTIDINE DEAMINASE; DNA; DNA METHYLATION; GENE EDITING; HEK293 CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEINS;

EID: 85054727008     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.4198     Document Type: Article

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