Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

Cell Death and Disease

Volumn 9, Issue 9, 2018, Pages

  Kim, Tae Woo ^a   Lee, Seon Young ^a   Kim, Mia ^a   Cheon, Chunhoo ^a   Ko, Seong Gyu ^a  

^a Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY RELATED PROTEIN; AUTOPHAGY RELATED PROTEIN 5; BECLIN 1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 12; CASPASE 9; CCAAT ENHANCER BINDING PROTEIN; CISPLATIN; HISTONE DEACETYLASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; KAEMPFEROL; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PROTEIN BCL 2; PROTEIN IRE1; PROTEIN SERINE THREONINE KINASE INHIBITOR; SBI 0206965; SEQUESTOSOME 1; SERINE THREONINE PROTEIN KINASE ULK1; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; THAPSIGARGIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DDIT3 PROTEIN, HUMAN; EHMT2 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HISTOCOMPATIBILITY ANTIGEN; HISTONE LYSINE METHYLTRANSFERASE; KAEMPFEROL DERIVATIVE; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

AGS CELL LINE; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CELL DEATH; CELL SURVIVAL; CYTOTOXICITY; DNA MODIFICATION; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; EPIGENETICS; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; MKN74 CELL LINE; NCI-N87 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SNU-216 CELL LINE; SNU-638 CELL LINE; STOMACH CANCER; TREATMENT RESPONSE; DRUG EFFECT; MAPK SIGNALING; METABOLISM; STOMACH TUMOR; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; KAEMPFEROLS; MAP KINASE SIGNALING SYSTEM; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSCRIPTION FACTOR CHOP;

EID: 85052717563     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/s41419-018-0930-1     Document Type: Article

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