Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma

Biochemical and Biophysical Research Communications

Volumn 459, Issue 1, 2015, Pages 10-17

  Ren, Aishu ^a   Qiu, Yu ^a   Cui, Hongjuan ^b   Fu, Gang ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b SOUTHWEST UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; G9a; Oral squamous cell carcinoma (OSCC)

Indexed keywords

CASPASE 3; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE G9A; LIGHT CHAIN 1; LIGHT CHAIN 3; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; PROTEIN; UNCLASSIFIED DRUG; AZEPINE DERIVATIVE; EHMT2 PROTEIN, HUMAN; ENZYME INHIBITOR; HISTOCOMPATIBILITY ANTIGEN; HISTONE LYSINE METHYLTRANSFERASE; QUINAZOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BRDU ASSAY; CANCER INHIBITION; CARCINOGENESIS; CARCINOMA CELL LINE; CELL GROWTH; CLONOGENESIS; COLONY FORMATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; METABOLISM; MOUTH NEOPLASMS; PATHOLOGY; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; AUTOPHAGY; AZEPINES; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME INHIBITORS; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; MICE, SCID; MOUTH NEOPLASMS; QUINAZOLINES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84930181780     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.068     Document Type: Article

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