Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP

Cell Death and Disease

Volumn 5, Issue 5, 2014, Pages

  Chen, L ^a   Xu, S ^a   Liu, L ^a   Wen, X ^a   Xu, Y ^a   Chen, J ^a,b   Teng, J ^a  

^a Peking University   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Apoptosis; Cab45S; ER stress; GRP78 BiP; IRE1; UPR

Indexed keywords

CAB45S PROTEIN; GLUCOSE REGULATED PROTEIN 78; INOSITOL REQUIRING KINASE 1; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CALCIUM-BINDING PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; GLYCOPROTEINS; HEAT-SHOCK PROTEINS; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN ISOFORMS; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; THAPSIGARGIN; TIME FACTORS; TRANSFECTION; TUNICAMYCIN;

EID: 84901022563     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.193     Document Type: Article

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