Overexpression of Insig-1 protects cell against glucolipotoxicity via SREBP-1c

Journal of Biomedical Science

Volumn 18, Issue 1, 2011, Pages

  Chen, Ke ^a   Jin, Ping ^a   He, Hong Hui ^a   Xie, Yan Hong ^a   Xie, Xiao Yun ^a   Mo, Zhao Hui ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; INSULIN INDUCED GENE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; PROTEIN BCL 2; REGULATOR PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; INSIG1 PROTEIN, RAT; LIPID; MEMBRANE PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; FATTY ACID SYNTHESIS; GENE ACTIVATION; GENE OVEREXPRESSION; GLUCOLIPOTOXICITY; GLUCOSE STIMULATED INSULIN SECRETION; INSULIN RELEASE; IRE 1ALPHA PROTEIN; LIPID METABOLISM; LIPID STORAGE; LIPOTOXICITY; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; INSULIN; INSULIN-SECRETING CELLS; LIPIDS; MEMBRANE PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 80051643447     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-18-57     Document Type: Article

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