메뉴 건너뛰기




Volumn 121, Issue , 2018, Pages 194-202

Follow that botanical: Challenges and recommendations for assessing absorption, distribution, metabolism and excretion of botanical dietary supplements

Author keywords

ADME; Botanical dietary supplements; Botanical drug interaction; Ginkgo biloba extract; Pharmacokinetics; Poly pharmacokinetics; Toxicokinetics

Indexed keywords

GINKGO BILOBA EXTRACT; HERBACEOUS AGENT; PHYTOCHEMICAL; PLANT EXTRACT; XENOBIOTIC AGENT;

EID: 85051210320     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2018.08.062     Document Type: Article
Times cited : (18)

References (88)
  • 1
    • 77950842156 scopus 로고    scopus 로고
    • An update on drug interactions with the herbal medicine. Ginkgo biloba
    • Abad, M.J., Bedoya, L.M., Bermejo, P., An update on drug interactions with the herbal medicine. Ginkgo biloba. Curr. Drug Metabol. 11 (2010), 171–181.
    • (2010) Curr. Drug Metabol. , vol.11 , pp. 171-181
    • Abad, M.J.1    Bedoya, L.M.2    Bermejo, P.3
  • 2
    • 59549092689 scopus 로고    scopus 로고
    • Complementary and alternative medicine use among adults and children: United States, 2007
    • Barnes, P.M., Bloom, B., Nahin, R.L., Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Report 12 (2008), 1–23.
    • (2008) Natl Health Stat Report , vol.12 , pp. 1-23
    • Barnes, P.M.1    Bloom, B.2    Nahin, R.L.3
  • 3
    • 0037287797 scopus 로고    scopus 로고
    • Medicinal properties of Echinacea: a critical review
    • Barrett, B., Medicinal properties of Echinacea: a critical review. Phytomedicine 1 (2003), 66–86.
    • (2003) Phytomedicine , vol.1 , pp. 66-86
    • Barrett, B.1
  • 5
    • 84937759749 scopus 로고    scopus 로고
    • Herbal Medicine, Biomolecular and Clinical Aspects, 2011
    • second ed. CRC Press/Taylor & Francis (978-1-4398-0713-2)
    • Benzie, I.F.F., Wachttel-Galor, S., Herbal Medicine, Biomolecular and Clinical Aspects, 2011. second ed., 2011, CRC Press/Taylor & Francis (ISBN-13: 978-1-4398-0713-2).
    • (2011)
    • Benzie, I.F.F.1    Wachttel-Galor, S.2
  • 7
    • 0042326246 scopus 로고    scopus 로고
    • Pharmacokinetics of Ginkgo biloba extracts
    • Biber, A., Pharmacokinetics of Ginkgo biloba extracts. Pharmacopsychiatry 36:Suppl. 1 (2003), S32–S37.
    • (2003) Pharmacopsychiatry , vol.36 , pp. S32-S37
    • Biber, A.1
  • 8
    • 0032989937 scopus 로고    scopus 로고
    • Bioavailability of ginkgolides and bilobalide from extracts of ginkgo biloba using GC/MS
    • Biber, A., Koch, E., Bioavailability of ginkgolides and bilobalide from extracts of ginkgo biloba using GC/MS. Planta Med. 65:2 (1999), 192–193.
    • (1999) Planta Med. , vol.65 , Issue.2 , pp. 192-193
    • Biber, A.1    Koch, E.2
  • 9
    • 77249169919 scopus 로고    scopus 로고
    • Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations
    • Brantley, S.J., Oberlies, N.H., Kroll, D.J., Paine, M.F., Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations. J. Pharmacol. Exp. Therapeut. 332:3 (2010), 1081–1087.
    • (2010) J. Pharmacol. Exp. Therapeut. , vol.332 , Issue.3 , pp. 1081-1087
    • Brantley, S.J.1    Oberlies, N.H.2    Kroll, D.J.3    Paine, M.F.4
  • 10
    • 84882789000 scopus 로고    scopus 로고
    • A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors
    • Brantley, S.J., Graf, T.N., Oberlies, N.H., Paine, M.F., A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors. Drug Metab. Dispos. 41:9 (2013), 1662–1670.
    • (2013) Drug Metab. Dispos. , vol.41 , Issue.9 , pp. 1662-1670
    • Brantley, S.J.1    Graf, T.N.2    Oberlies, N.H.3    Paine, M.F.4
  • 11
    • 84893839263 scopus 로고    scopus 로고
    • Herb-drug interactions: challenges and opportunities for improved predictions
    • Brantley, S.J., Argikar, A.A., Lin, Y.S., Nagar, S., Paine, M.F., Herb-drug interactions: challenges and opportunities for improved predictions. Drug Metab. Dispos. 42:3 (2014), 301–317.
    • (2014) Drug Metab. Dispos. , vol.42 , Issue.3 , pp. 301-317
    • Brantley, S.J.1    Argikar, A.A.2    Lin, Y.S.3    Nagar, S.4    Paine, M.F.5
  • 17
    • 84883255312 scopus 로고    scopus 로고
    • Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of admistration
    • Cheng, F., Li, L., Xu, F., Sun, Y., Du, F., Ma, X., Zhong, C., Li, X., Wang, F., Zhang, N., Li, C., Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of admistration. Britsh J. Pharm. 170 (2013), 440–457.
    • (2013) Britsh J. Pharm. , vol.170 , pp. 440-457
    • Cheng, F.1    Li, L.2    Xu, F.3    Sun, Y.4    Du, F.5    Ma, X.6    Zhong, C.7    Li, X.8    Wang, F.9    Zhang, N.10    Li, C.11
  • 18
    • 84922817862 scopus 로고    scopus 로고
    • Trends in the use of complementary health approaches among adults: United States, 2002-2012
    • Clarke, T.C., Black, L.I., Stussman, B.J., Barnes, P.M., Nahin, R.L., Trends in the use of complementary health approaches among adults: United States, 2002-2012. Natl. Health. Stat. Rep. 79 (2015), 1–16.
    • (2015) Natl. Health. Stat. Rep. , vol.79 , pp. 1-16
    • Clarke, T.C.1    Black, L.I.2    Stussman, B.J.3    Barnes, P.M.4    Nahin, R.L.5
  • 19
    • 0022239276 scopus 로고
    • Risk assessment extrapolations and physiological modeling
    • Clewell, H.J. III, Anderson, M.E., Risk assessment extrapolations and physiological modeling. Toxicol. Ind. Health 4 (1985), 111–131.
    • (1985) Toxicol. Ind. Health , vol.4 , pp. 111-131
    • Clewell, H.J.1    Anderson, M.E.2
  • 20
    • 0042827395 scopus 로고    scopus 로고
    • A brief history of EGb761 and its therapeutic uses
    • deFeudis, F.V., A brief history of EGb761 and its therapeutic uses. Pharmacopsychiatry 36 (2003), S2–S7.
    • (2003) Pharmacopsychiatry , vol.36 , pp. S2-S7
    • deFeudis, F.V.1
  • 23
    • 35748961687 scopus 로고    scopus 로고
    • Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system
    • Dunnick, J.K., Kissling, G., Gerken, D.K., Vallant, M.A., Nyska, A., Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system. Toxicol. Pathol. 35:5 (2007), 657–664.
    • (2007) Toxicol. Pathol. , vol.35 , Issue.5 , pp. 657-664
    • Dunnick, J.K.1    Kissling, G.2    Gerken, D.K.3    Vallant, M.A.4    Nyska, A.5
  • 24
    • 0000431698 scopus 로고    scopus 로고
    • Black cohosh: a literature review
    • Foster, S., Black cohosh: a literature review. Herbalgram. Winter, 1999, 35–49.
    • (1999) Herbalgram. Winter , pp. 35-49
    • Foster, S.1
  • 25
    • 0029016057 scopus 로고
    • Pharmacokinetic properties of Bilobalide and Ginkgolides A and B in healthy subjects after intravenous and oral administration of Ginkgo biloba extract (EGb761)
    • Fourtillan, J.B., Brisson, A.M., Girault, J., Ingrand, I., Decourt, J.P., Drieu, K., Jouenne, P., Biber, A., Pharmacokinetic properties of Bilobalide and Ginkgolides A and B in healthy subjects after intravenous and oral administration of Ginkgo biloba extract (EGb761). Therapie 50:2 (1995), 137–144.
    • (1995) Therapie , vol.50 , Issue.2 , pp. 137-144
    • Fourtillan, J.B.1    Brisson, A.M.2    Girault, J.3    Ingrand, I.4    Decourt, J.P.5    Drieu, K.6    Jouenne, P.7    Biber, A.8
  • 26
    • 79251505591 scopus 로고    scopus 로고
    • Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba
    • Fransen, H.P., Pelgrom, S.M., Stewart-Knox, B., de Kaste, D., Verhagen, H., Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba. Food Nutr. Res., 30, 2010, 54.
    • (2010) Food Nutr. Res. , vol.30 , pp. 54
    • Fransen, H.P.1    Pelgrom, S.M.2    Stewart-Knox, B.3    de Kaste, D.4    Verhagen, H.5
  • 27
    • 84940434450 scopus 로고    scopus 로고
    • Milk thistle constituents inhibit raloxifene intestinal glucuronidation: a potential clinically relevant natural product-drug interaction
    • Gufford, B.T., Chen, G., Vergara, A.G., Lazarus, P., Oberlies, N.H., Paine, M.F., Milk thistle constituents inhibit raloxifene intestinal glucuronidation: a potential clinically relevant natural product-drug interaction. Drug Metab. Dispos. 43:9 (2015), 1353–1359.
    • (2015) Drug Metab. Dispos. , vol.43 , Issue.9 , pp. 1353-1359
    • Gufford, B.T.1    Chen, G.2    Vergara, A.G.3    Lazarus, P.4    Oberlies, N.H.5    Paine, M.F.6
  • 29
    • 84866109213 scopus 로고    scopus 로고
    • Pharmacokinetic herb-drug interactions (Part 1): origins, mechansims, and the impact of botanical dietary supplements
    • Gurley, B.J., Pharmacokinetic herb-drug interactions (Part 1): origins, mechansims, and the impact of botanical dietary supplements. Planta Med. 78:13 (2012), 1478–1489.
    • (2012) Planta Med. , vol.78 , Issue.13 , pp. 1478-1489
    • Gurley, B.J.1
  • 30
    • 22344453862 scopus 로고    scopus 로고
    • Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: st. John's wort, garlic oil, Panax ginseng, and Ginkgo biloba
    • Gurley, B.J., Gardner, S.F., Hubbard, M.A., Williams, D.K., Gentry, W.B., Cui, Y., Ang, C.Y.W., Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: st. John's wort, garlic oil, Panax ginseng, and Ginkgo biloba. Drugs Aging 22:6 (2005), 525–539.
    • (2005) Drugs Aging , vol.22 , Issue.6 , pp. 525-539
    • Gurley, B.J.1    Gardner, S.F.2    Hubbard, M.A.3    Williams, D.K.4    Gentry, W.B.5    Cui, Y.6    Ang, C.Y.W.7
  • 31
    • 85027924798 scopus 로고    scopus 로고
    • Pharmacokinetic herb-drug interactions (Part 2): drug interactions involving popular botanical detary supplements and their clinical relevance
    • Gurley, B.J., Fifer, E.K., Gardner, Z., Pharmacokinetic herb-drug interactions (Part 2): drug interactions involving popular botanical detary supplements and their clinical relevance. Planta Med. 78 (2012), 1490–1514.
    • (2012) Planta Med. , vol.78 , pp. 1490-1514
    • Gurley, B.J.1    Fifer, E.K.2    Gardner, Z.3
  • 32
    • 85028922119 scopus 로고    scopus 로고
    • Practical considerations when designing and conducting clinical pharmacokinetic herb-drug interaction studies
    • Gurley, B.J., Markowitz, J.S., Williams, D.K., Barone, G.W., Practical considerations when designing and conducting clinical pharmacokinetic herb-drug interaction studies. Int. J. Pharmacokinetics. 2:1 (2017), 57–69.
    • (2017) Int. J. Pharmacokinetics. , vol.2 , Issue.1 , pp. 57-69
    • Gurley, B.J.1    Markowitz, J.S.2    Williams, D.K.3    Barone, G.W.4
  • 33
    • 79958290393 scopus 로고    scopus 로고
    • ADME properties of herbal medicines in humans: evidence, challenges and strategies
    • He, S.M., Chan, E., Zhou, S.F., ADME properties of herbal medicines in humans: evidence, challenges and strategies. Curr. Pharmaceut. Des. 17:4 (2011), 357–407.
    • (2011) Curr. Pharmaceut. Des. , vol.17 , Issue.4 , pp. 357-407
    • He, S.M.1    Chan, E.2    Zhou, S.F.3
  • 34
    • 0026529471 scopus 로고
    • A strategy for discovering biologically active compounds with high probability in traditional Chinese herb remedies: an application of saiboku-to in bronchial asthma
    • Homma, M., Oka, K., Yamada, T., Niitsuma, T., Ihto, H., Takahashi, N., A strategy for discovering biologically active compounds with high probability in traditional Chinese herb remedies: an application of saiboku-to in bronchial asthma. Anal. Biochem. 202:1 (1992), 179–187.
    • (1992) Anal. Biochem. , vol.202 , Issue.1 , pp. 179-187
    • Homma, M.1    Oka, K.2    Yamada, T.3    Niitsuma, T.4    Ihto, H.5    Takahashi, N.6
  • 35
    • 85026550712 scopus 로고    scopus 로고
    • The polypharmacokinetics of herbal medicines
    • Jia, W., Fan, T.P., Wang, X.N., Xie, G.X., The polypharmacokinetics of herbal medicines. Science 350 (2015), S76–S79.
    • (2015) Science , vol.350 , pp. S76-S79
    • Jia, W.1    Fan, T.P.2    Wang, X.N.3    Xie, G.X.4
  • 36
    • 77949368190 scopus 로고    scopus 로고
    • Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment
    • Jordan, S.A., Cunningham, D.G., Marles, R.J., Assessment of herbal medicinal products: challenges, and opportunities to increase the knowledge base for safety assessment. Toxicol. Appl. Pharmacol. 243 (2010), 198–216.
    • (2010) Toxicol. Appl. Pharmacol. , vol.243 , pp. 198-216
    • Jordan, S.A.1    Cunningham, D.G.2    Marles, R.J.3
  • 37
    • 84922509877 scopus 로고    scopus 로고
    • Echinacea for preventing and treating the common cold
    • Karsch-Völk, M., Barrett, B., Linde, K., Echinacea for preventing and treating the common cold. J. Am. Med. Assoc. 6 (2015), 618–619.
    • (2015) J. Am. Med. Assoc. , vol.6 , pp. 618-619
    • Karsch-Völk, M.1    Barrett, B.2    Linde, K.3
  • 38
    • 0037116642 scopus 로고    scopus 로고
    • Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey
    • Kaufman, D.W., Kelly, J.P., Rosenberg, L., Anderson, T.E., Mitchell, A.A., Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. J. Am. Med. Assoc. 287 (2002), 337–344.
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 337-344
    • Kaufman, D.W.1    Kelly, J.P.2    Rosenberg, L.3    Anderson, T.E.4    Mitchell, A.A.5
  • 39
    • 84937786508 scopus 로고    scopus 로고
    • Effect of natural polyphenols on CYP metabolism: implications for diseases
    • Korobkova, E.A., Effect of natural polyphenols on CYP metabolism: implications for diseases. Chem. Res. Toxicol. 28 (2015), 1359–1390.
    • (2015) Chem. Res. Toxicol. , vol.28 , pp. 1359-1390
    • Korobkova, E.A.1
  • 40
    • 0036849186 scopus 로고    scopus 로고
    • Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations
    • Kressmann, S., Biber, A., Wonnemann, M., Schug, B., Blume, H.H., Müller, W.E., Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations. J. Pharm. Pharmacol. 54:11 (2002), 1507–1514.
    • (2002) J. Pharm. Pharmacol. , vol.54 , Issue.11 , pp. 1507-1514
    • Kressmann, S.1    Biber, A.2    Wonnemann, M.3    Schug, B.4    Blume, H.H.5    Müller, W.E.6
  • 41
    • 72149118194 scopus 로고    scopus 로고
    • Hepatotoxicity of high oral dose (−)-epigallocatechin-3-gallate in mice
    • Lambert, J.D., Kennett, M.J., Sang, S., Reuhl, K.R., Ju, J., Yang, C.S., Hepatotoxicity of high oral dose (−)-epigallocatechin-3-gallate in mice. Food Chem. Toxicol. 48:1 (2010), 409–416.
    • (2010) Food Chem. Toxicol. , vol.48 , Issue.1 , pp. 409-416
    • Lambert, J.D.1    Kennett, M.J.2    Sang, S.3    Reuhl, K.R.4    Ju, J.5    Yang, C.S.6
  • 42
    • 77950803183 scopus 로고    scopus 로고
    • An integrated metabolomics and pharmacokinetics strategy for multi-component drugs evaluation
    • Lan, K., Jia, W., An integrated metabolomics and pharmacokinetics strategy for multi-component drugs evaluation. Curr. Drug Metabol. 11 (2010), 105–114.
    • (2010) Curr. Drug Metabol. , vol.11 , pp. 105-114
    • Lan, K.1    Jia, W.2
  • 43
    • 84876567681 scopus 로고    scopus 로고
    • Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach
    • 819147
    • Lan, K., Xie, G., Jia, W., Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach. Evid. Base. Compl. Alternat. Med., 2013, 2013 http://dx.doi.org/10.1155/2013/819147 819147.
    • (2013) Evid. Base. Compl. Alternat. Med. , vol.2013
    • Lan, K.1    Xie, G.2    Jia, W.3
  • 44
    • 84873028242 scopus 로고    scopus 로고
    • Black cohosh (Cimicifuga spp.) for menopausal symptoms
    • Leach, M.J., Moore, V., Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database Syst. Rev.(9), 2012, CD007244.
    • (2012) Cochrane Database Syst. Rev. , Issue.9 , pp. CD007244
    • Leach, M.J.1    Moore, V.2
  • 45
    • 85033586105 scopus 로고    scopus 로고
    • Incidence of pyrrolizidine alkaloids in herbal medicines from German retail markets: risk assessment and inplications to consumers
    • Letsyo, E., Jerz, G., Winterhalter, P., Lindigkeit, R., Beuerle, T., Incidence of pyrrolizidine alkaloids in herbal medicines from German retail markets: risk assessment and inplications to consumers. Phytother Res. 31 (2017), 1903–1909.
    • (2017) Phytother Res. , vol.31 , pp. 1903-1909
    • Letsyo, E.1    Jerz, G.2    Winterhalter, P.3    Lindigkeit, R.4    Beuerle, T.5
  • 46
    • 77954175046 scopus 로고    scopus 로고
    • Qualitative and quantitative determination of complicated herbal components by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a relative exposure approach to herbal pharmacokinetics independent of standards
    • Liang, Y., Hao, H., Kanga, A., Xie, L., Xiea, T., Zhenga, X., Daia, C., Wanb, L., Shenga, L., Wanga, G., Qualitative and quantitative determination of complicated herbal components by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a relative exposure approach to herbal pharmacokinetics independent of standards. J. Chromatogr. A 30 (2010), 4971–4979.
    • (2010) J. Chromatogr. A , vol.30 , pp. 4971-4979
    • Liang, Y.1    Hao, H.2    Kanga, A.3    Xie, L.4    Xiea, T.5    Zhenga, X.6    Daia, C.7    Wanb, L.8    Shenga, L.9    Wanga, G.10
  • 49
    • 32444439705 scopus 로고    scopus 로고
    • LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity
    • Mauri, P., De Palma, A., Pozzi, F., Basilico, F., Riva, A., Morazzoni, P., Bombardelli, E., Rossoni, G., LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity. J. Pharmaceut. Biomed. Anal. 40:3 (2006), 763–768.
    • (2006) J. Pharmaceut. Biomed. Anal. , vol.40 , Issue.3 , pp. 763-768
    • Mauri, P.1    De Palma, A.2    Pozzi, F.3    Basilico, F.4    Riva, A.5    Morazzoni, P.6    Bombardelli, E.7    Rossoni, G.8
  • 50
    • 0034961776 scopus 로고    scopus 로고
    • Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts
    • Mauri, P., Simonetti, P., Gardana, C., Minoggio, M., Morazzoni, P., Bombardelli, E., Pietta, P., Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts. Rapid Commun. Mass Spectrom. 15:12 (2001), 929–934.
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , Issue.12 , pp. 929-934
    • Mauri, P.1    Simonetti, P.2    Gardana, C.3    Minoggio, M.4    Morazzoni, P.5    Bombardelli, E.6    Pietta, P.7
  • 52
    • 85052896178 scopus 로고    scopus 로고
    • NTP technical report on the toxicology and carcinogenesis studies of kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice
    • National Toxicology Program (NTP), NTP technical report on the toxicology and carcinogenesis studies of kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice. Natl. Toxicol. Progr. Tech. Rep., 571, 2012.
    • (2012) Natl. Toxicol. Progr. Tech. Rep. , vol.571
  • 53
    • 84888858395 scopus 로고    scopus 로고
    • NTP technical report on the toxicology and carcinogenesis studies of ginkgo biloba extract (CAS No. 90045-36-6) in F344/N rats and B6C3F1/N mice
    • National Toxicology Program (NTP), NTP technical report on the toxicology and carcinogenesis studies of ginkgo biloba extract (CAS No. 90045-36-6) in F344/N rats and B6C3F1/N mice. Natl. Toxicol. Progr. Tech. Rep., 578, 2013.
    • (2013) Natl. Toxicol. Progr. Tech. Rep. , vol.578
  • 54
    • 84948654270 scopus 로고    scopus 로고
    • Toxicology studies of green tea extract in F344/NTac rats and B6C3F1/N mice and Toxicology and carcinogenesis studies of green tea extract in Wistar Han[Crl:Wi(Han)] rats and B6C3F1/N mice
    • National Toxicology Program (NTP), Toxicology studies of green tea extract in F344/NTac rats and B6C3F1/N mice and Toxicology and carcinogenesis studies of green tea extract in Wistar Han[Crl:Wi(Han)] rats and B6C3F1/N mice. Natl. Toxicol. Progr. Tech. Rep., 585, 2014.
    • (2014) Natl. Toxicol. Progr. Tech. Rep. , vol.585
  • 56
    • 85021870410 scopus 로고    scopus 로고
    • The global regulatory framework for medicinal plants
    • Picking, D., The global regulatory framework for medicinal plants. Pharmacognosy:Fundamentals. Appl. Strat., 2017, 663–675.
    • (2017) Pharmacognosy:Fundamentals. Appl. Strat. , pp. 663-675
    • Picking, D.1
  • 57
    • 84929378988 scopus 로고    scopus 로고
    • Implications of green tea and its constituents in the prevention of cancer via the modulation of cell signalling pathway
    • Rahmani, A.H., Al shabrmi, F.M., Allemailem, K.S., Aly, S.M., Khan, M.A., Implications of green tea and its constituents in the prevention of cancer via the modulation of cell signalling pathway. BioMed Res. Int., 2015, 2015, 925640.
    • (2015) BioMed Res. Int. , vol.2015 , pp. 925640
    • Rahmani, A.H.1    Al shabrmi, F.M.2    Allemailem, K.S.3    Aly, S.M.4    Khan, M.A.5
  • 58
    • 85033230692 scopus 로고    scopus 로고
    • Prevalence and predictors of herbal medicine use among adults in the United States
    • Rashrash, M., Schommer, J.C., Brown, L.M., Prevalence and predictors of herbal medicine use among adults in the United States. J. Patient Exp. 4:3 (2017), 108–113.
    • (2017) J. Patient Exp. , vol.4 , Issue.3 , pp. 108-113
    • Rashrash, M.1    Schommer, J.C.2    Brown, L.M.3
  • 62
    • 66049161455 scopus 로고    scopus 로고
    • Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of bilobalide in plasma and brain of rats after oral administration of its phospholipidic complex
    • Rossi, R., Basilico, F., Rossoni, G., Riva, A., Morazzoni, P., Mauri, P.L., Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of bilobalide in plasma and brain of rats after oral administration of its phospholipidic complex. J. Pharmaceut. Biomed. Anal. 50:2 (2009), 224–227.
    • (2009) J. Pharmaceut. Biomed. Anal. , vol.50 , Issue.2 , pp. 224-227
    • Rossi, R.1    Basilico, F.2    Rossoni, G.3    Riva, A.4    Morazzoni, P.5    Mauri, P.L.6
  • 68
    • 85045053099 scopus 로고    scopus 로고
    • Herbal supplement sales in US increase 7.7% in 2016. Consumer preferences shifting toward ingredients with general wellness benefits, driving growth of adaptogens and digestive health products
    • Smith, T., Kawa, K., Eckl, V., Morton, C., Strednev, R., Herbal supplement sales in US increase 7.7% in 2016. Consumer preferences shifting toward ingredients with general wellness benefits, driving growth of adaptogens and digestive health products. HerbalGram 115 (2017), 56–65.
    • (2017) HerbalGram , vol.115 , pp. 56-65
    • Smith, T.1    Kawa, K.2    Eckl, V.3    Morton, C.4    Strednev, R.5
  • 70
    • 84958157318 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between drugs and botanical dietary supplements
    • Sprouse, A.A., van Breemen, R.B., Pharmacokinetic interactions between drugs and botanical dietary supplements. Drug Metab. Dispos. 44 (2015), 162–171.
    • (2015) Drug Metab. Dispos. , vol.44 , pp. 162-171
    • Sprouse, A.A.1    van Breemen, R.B.2
  • 71
    • 84969718887 scopus 로고    scopus 로고
    • Effect of the anti-depressant sertraline, the novel anti-seizure drug vinpocetine and several conventional antiepileptic drugs on the epileptiform EEG activity induced by 4-aminopyridine
    • Sitges, M., Aldana, B.I., Reed, R.C., Effect of the anti-depressant sertraline, the novel anti-seizure drug vinpocetine and several conventional antiepileptic drugs on the epileptiform EEG activity induced by 4-aminopyridine. Neurochem. Res. 41 (2016), 1365–1374.
    • (2016) Neurochem. Res. , vol.41 , pp. 1365-1374
    • Sitges, M.1    Aldana, B.I.2    Reed, R.C.3
  • 72
    • 84867531046 scopus 로고    scopus 로고
    • Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review
    • Tsai, H.H., Lin, H.W., Simon Pickard, A., Tsai, H.Y., Mahady, G.B., Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature review. Int. J. Clin. Pract. 66 (2012), 1056–1078.
    • (2012) Int. J. Clin. Pract. , vol.66 , pp. 1056-1078
    • Tsai, H.H.1    Lin, H.W.2    Simon Pickard, A.3    Tsai, H.Y.4    Mahady, G.B.5
  • 73
    • 79551683865 scopus 로고    scopus 로고
    • Plasma and brain levels of terpene trilactones in rats after an oral single dose of standardized Ginkgo biloba extract EGb 761
    • Ude, C., Paulke, A., Nöldner, M., Schubert-Zsilavecz, M., Wurglics, M., Plasma and brain levels of terpene trilactones in rats after an oral single dose of standardized Ginkgo biloba extract EGb 761. Planta Med. 77:3 (2011), 259–264.
    • (2011) Planta Med. , vol.77 , Issue.3 , pp. 259-264
    • Ude, C.1    Paulke, A.2    Nöldner, M.3    Schubert-Zsilavecz, M.4    Wurglics, M.5
  • 74
    • 84883187015 scopus 로고    scopus 로고
    • Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients
    • Ude, C., Schubert-Zsilavecz, M., Wurglics, M., Ginkgo biloba extracts: a review of the pharmacokinetics of the active ingredients. Clin. Pharmacokinet. 52 (2013), 727–749.
    • (2013) Clin. Pharmacokinet. , vol.52 , pp. 727-749
    • Ude, C.1    Schubert-Zsilavecz, M.2    Wurglics, M.3
  • 75
    • 84880533608 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions involving Ginkgo biloba
    • Unger, M., Pharmacokinetic drug interactions involving Ginkgo biloba. Drug Metab. Rev. 45:3 (2013), 353–385.
    • (2013) Drug Metab. Rev. , vol.45 , Issue.3 , pp. 353-385
    • Unger, M.1
  • 76
    • 0011676307 scopus 로고
    • Dietary Supplement Health and Education Act
    • National Institutes of Health Office of Dietary Supplements (accessed Februrary 20, 2017)
    • U.S. Department of Health and Human Services (DHHS), Dietary Supplement Health and Education Act. 1994, National Institutes of Health Office of Dietary Supplements http://ods.od.nih.gov/About/dshea_ wording.aspx (accessed Februrary 20, 2017).
    • (1994)
  • 77
    • 0037118913 scopus 로고    scopus 로고
    • Chemical analysis of Ginkgo biloba leaves and extracts
    • van Beek, T.A., Chemical analysis of Ginkgo biloba leaves and extracts. J. Chromatogr. A 967 (2002), 21–55.
    • (2002) J. Chromatogr. A , vol.967 , pp. 21-55
    • van Beek, T.A.1
  • 78
    • 34248597940 scopus 로고    scopus 로고
    • The role of quality assurance and standardization in the safety of botanical dietary supplements
    • van Breemen, R.B., Fong, H.H., Farnsworth, N.R., The role of quality assurance and standardization in the safety of botanical dietary supplements. Chem. Res. Toxicol. 20:4 (2007), 577–582.
    • (2007) Chem. Res. Toxicol. , vol.20 , Issue.4 , pp. 577-582
    • van Breemen, R.B.1    Fong, H.H.2    Farnsworth, N.R.3
  • 80
    • 85034607503 scopus 로고    scopus 로고
    • Systemic exposure of vinpocetine in pregnant Sprague Dawley rats following repeated oral exposure: an investigation of fetal transfer
    • Waidyanatha, S., Toy, H., South, N., Gibbs, S., Mutlu, E., Burback, B., McIntyre, B.S., Catlin, N., Systemic exposure of vinpocetine in pregnant Sprague Dawley rats following repeated oral exposure: an investigation of fetal transfer. Toxicol. Appl. Pharmacol. 1:338 (2018), 83–92.
    • (2018) Toxicol. Appl. Pharmacol. , vol.1 , Issue.338 , pp. 83-92
    • Waidyanatha, S.1    Toy, H.2    South, N.3    Gibbs, S.4    Mutlu, E.5    Burback, B.6    McIntyre, B.S.7    Catlin, N.8
  • 81
    • 26644447398 scopus 로고    scopus 로고
    • LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui
    • Wang, Y.L., Liang, Y.Z., Chen, B.M., He, Y.K., Li, B.Y., Hu, Q.N., LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui. Anal. Bioanal. Chem. 383:2 (2005), 247–254.
    • (2005) Anal. Bioanal. Chem. , vol.383 , Issue.2 , pp. 247-254
    • Wang, Y.L.1    Liang, Y.Z.2    Chen, B.M.3    He, Y.K.4    Li, B.Y.5    Hu, Q.N.6
  • 82
    • 33846210599 scopus 로고    scopus 로고
    • Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry
    • Wang, P., Liang, Y.Z., Zhou, N., Chen, B.M., Yi, L.Z., Yu, Y., Yi, Z.B., Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry. Rapid Commun. Mass Spectrom. 21:2 (2007), 99–106.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , Issue.2 , pp. 99-106
    • Wang, P.1    Liang, Y.Z.2    Zhou, N.3    Chen, B.M.4    Yi, L.Z.5    Yu, Y.6    Yi, Z.B.7
  • 83
    • 37749026053 scopus 로고    scopus 로고
    • Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOFMS/MS
    • Wang, X.J., Sun, W.J., Sun, H., Lv, H.T., Wu, Z.M., Wang, P., Liu, L., Cao, H.X., Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOFMS/MS. J. Pharmaceut. Biomed. Anal. 46:3 (2008), 477–490.
    • (2008) J. Pharmaceut. Biomed. Anal. , vol.46 , Issue.3 , pp. 477-490
    • Wang, X.J.1    Sun, W.J.2    Sun, H.3    Lv, H.T.4    Wu, Z.M.5    Wang, P.6    Liu, L.7    Cao, H.X.8
  • 84
    • 79951581524 scopus 로고    scopus 로고
    • A bio-activity guided in vitro pharmacokinetic method to improve the quality control of Chinese medicines, application to Si Wu Tang
    • Wang, L., Wang, Z., Wo, S., Lau, C.B., Chen, X., Huang, M., Lee, V.H., Chow, M.S., Zuo, Z., A bio-activity guided in vitro pharmacokinetic method to improve the quality control of Chinese medicines, application to Si Wu Tang. Int. J. Pharm. 406 (2011), 99–105.
    • (2011) Int. J. Pharm. , vol.406 , pp. 99-105
    • Wang, L.1    Wang, Z.2    Wo, S.3    Lau, C.B.4    Chen, X.5    Huang, M.6    Lee, V.H.7    Chow, M.S.8    Zuo, Z.9
  • 85
    • 77349104616 scopus 로고    scopus 로고
    • Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans
    • Woelkart, K., Feizlmayr, E., Dittrich, P., Beubler, E., Pinl, F., Suter, A., Bauer, R., Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans. Phytother Res. 24:3 (2010), 445–450.
    • (2010) Phytother Res. , vol.24 , Issue.3 , pp. 445-450
    • Woelkart, K.1    Feizlmayr, E.2    Dittrich, P.3    Beubler, E.4    Pinl, F.5    Suter, A.6    Bauer, R.7
  • 87
    • 11144317888 scopus 로고    scopus 로고
    • Chemical fingerprint and metabolic fingerprint analysis of Danshen injection by HPLC-UV and HPLC-MS methods
    • Zhang, J.L., Cui, M., He, Y., Yu, H.L., Guo, D.A., Chemical fingerprint and metabolic fingerprint analysis of Danshen injection by HPLC-UV and HPLC-MS methods. J. Pharm.Biomed. Anal. 36:5 (2005), 1029–1035.
    • (2005) J. Pharm.Biomed. Anal. , vol.36 , Issue.5 , pp. 1029-1035
    • Zhang, J.L.1    Cui, M.2    He, Y.3    Yu, H.L.4    Guo, D.A.5
  • 88
    • 84934285721 scopus 로고    scopus 로고
    • Proliposomes containing a bile salt for oral delivery of Ginkgo biloba extract: formulation optimization, characterization, oral bioavailability and tissue distribution in rats
    • Zheng, B., Teng, L., Xing, G., Bi, Y., Yang, S., Hao, F., Yan, G., Wang, X., Lee, R.J., Teng, L., Xi, J., Proliposomes containing a bile salt for oral delivery of Ginkgo biloba extract: formulation optimization, characterization, oral bioavailability and tissue distribution in rats. Eur. J. Pharmaceut. Sci. 77 (2015), 254–264.
    • (2015) Eur. J. Pharmaceut. Sci. , vol.77 , pp. 254-264
    • Zheng, B.1    Teng, L.2    Xing, G.3    Bi, Y.4    Yang, S.5    Hao, F.6    Yan, G.7    Wang, X.8    Lee, R.J.9    Teng, L.10    Xi, J.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.