Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of bilobalide in plasma and brain of rats after oral administration of its phospholipidic complex

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 2, 2009, Pages 224-227

  Rossi, Rossana ^a   Basilico, Fabrizio ^a   Rossoni, Giuseppe ^b   Riva, Antonella ^c   Morazzoni, Paolo ^c   Mauri, Pier Luigi ^a  

^a INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c INDENA S P A   (Italy)

Author keywords

Bilobalide; Brain; Ginkgo biloba; LC APCI ITMS; Pharmacokinetics; Plasma

Indexed keywords

BILOBALIDE; GINKGO BILOBA EXTRACT; GLYCYRRHETINIC ACID PHOSPHOLIPID COMPLEX; LACTONE; TERPENE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DOSE INCREASE; DRUG TRANSPORT; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY;

ADMINISTRATION, ORAL; ANIMALS; ATMOSPHERIC PRESSURE; BIOLOGICAL AVAILABILITY; BRAIN; CALIBRATION; CYCLOPENTANES; FURANS; GINKGOLIDES; MALE; MASS SPECTROMETRY; PHOSPHOLIPIDS; RATS; REFERENCE STANDARDS;

EID: 66049161455     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.04.026     Document Type: Article

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