Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice

Food and Chemical Toxicology

Volumn 48, Issue 1, 2010, Pages 409-416

  Lambert, Joshua D ^a   Kennett, Mary J ^a   Sang, Shengmin ^b   Reuhl, Kenneth R ^c   Ju, Jihyeung ^c   Yang, Chung S ^c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

( ) Epigallocatechin 3 gallate; Green tea; Hepatotoxicity; Mouse; Oxidative stress

Indexed keywords

8 ISOPROSTANE; ALANINE AMINOTRANSFERASE; EPIGALLOCATECHIN GALLATE; HISTONE; INTERLEUKIN 6; METALLOTHIONEIN; MONOCYTE CHEMOTACTIC PROTEIN 1;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; LIPID PEROXIDATION; LIVER NECROSIS; LIVER TOXICITY; MALE; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SINGLE DRUG DOSE; TOXICITY TESTING;

ALDEHYDES; ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; CATECHIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LIVER FUNCTION TESTS; MALE; METALLOTHIONEIN; MICE; OXIDANTS; OXIDATIVE STRESS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURVIVAL ANALYSIS;

MUS;

EID: 72149118194     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.10.030     Document Type: Article

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