Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional

Scientific Reports

Volumn 8, Issue 1, 2018, Pages

  Toda, Yasuka ^a,b   Nakagita, Tomoya ^a,c   Hirokawa, Takatsugu ^d   Yamashita, Yuki ^e   Nakajima, Ayako ^e   Narukawa, Masataka ^a   Ishimaru, Yoshiro ^b   Uchida, Riichiro ^e   Misaka, Takumi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MEIJI UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^e KIKKOMAN CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; FUSION PROTEIN; G PROTEIN COUPLED RECEPTOR; METHIONAL; TASTE RECEPTORS, TYPE 1;

ALLOSTERISM; ANIMAL; BINDING SITE; CHEMISTRY; GENETICS; HUMAN; MOLECULAR MODEL; MOUSE; SITE DIRECTED MUTAGENESIS;

ALDEHYDES; ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; HUMANS; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS;

EID: 85051174448     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-018-30315-x     Document Type: Article

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