Spermidine prevents high glucose-induced senescence in HT-22 cells by upregulation of CB1 receptor

Clinical and Experimental Pharmacology and Physiology

Volumn 45, Issue 8, 2018, Pages 832-840

  Zhu, Wei Wen ^a   Xiao, Fan ^a   Tang, Yi Yun ^a   Zou, Wei ^a   Li, Xiang ^a   Zhang, Ping ^a   Wang, Ai Ping ^a   Tang, Xiao Qing ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

CB1 receptor; diabetic encephalopathy; high glucose; hyperglyceamia; senescence; spermidine

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; BETA GALACTOSIDASE; CANNABINOID 1 RECEPTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GLUCOSE; SPERMIDINE;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL AGING; CELL COUNTING; CELL CULTURE; CELL VIABILITY; DRUG MECHANISM; HT22 CELL LINE; IN VITRO STUDY; MOUSE; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE TECHNIQUE; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; METABOLISM; NERVE CELL; PATHOLOGY; UPREGULATION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; CELLULAR SENESCENCE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; MICE; NEURONS; RECEPTOR, CANNABINOID, CB1; SPERMIDINE; UP-REGULATION;

EID: 85050471498     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12955     Document Type: Article

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