메뉴 건너뛰기




Volumn 54, Issue 5, 2017, Pages 417-424

Cognitive impairment and dementia: a new emerging complication of type 2 diabetes—The diabetologist’s perspective

Author keywords

Alzheimer s disease; Cognitive impairment; Dementia; Type 2 diabetes

Indexed keywords

ADVANCED GLYCATION END PRODUCT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; INSULIN; INSULIN DEGLUDEC; INSULIN GLARGINE; LONG ACTING INSULIN; METFORMIN; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE;

EID: 85013078291     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-017-0970-5     Document Type: Article
Times cited : (137)

References (47)
  • 2
    • 67649742213 scopus 로고    scopus 로고
    • Risk of incident alzheimer’s disease in diabetic patients: a systematic review of prospective trials
    • Kopf D, Frölich L (2009) Risk of incident alzheimer’s disease in diabetic patients: a systematic review of prospective trials. J Alzheimer Dis 16:677–685
    • (2009) J Alzheimer Dis , vol.16 , pp. 677-685
    • Kopf, D.1    Frölich, L.2
  • 4
    • 84875354777 scopus 로고    scopus 로고
    • Alzheimer’s disease facts and figures
    • Thies W, Bleiler L, Alzheimer’s Association (2013) Alzheimer’s disease facts and figures. Alzheimer Dement 9:208–245
    • (2013) Alzheimer Dement , vol.9 , pp. 208-245
    • Thies, W.1    Bleiler, L.2
  • 6
    • 84860850000 scopus 로고    scopus 로고
    • Risk of alzheimer’s disease in relation to diabetes: a population-based cohort study
    • PID: 22572745
    • Wang KC, Woung LC, Tsai MT, Liu CC, Su YH, Li CY (2012) Risk of alzheimer’s disease in relation to diabetes: a population-based cohort study. Neuroepidemiology 38:237–244
    • (2012) Neuroepidemiology , vol.38 , pp. 237-244
    • Wang, K.C.1    Woung, L.C.2    Tsai, M.T.3    Liu, C.C.4    Su, Y.H.5    Li, C.Y.6
  • 7
    • 84899414414 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of alzheimer’s disease: a nationwide population-based study
    • PID: 24489845
    • Huang CC, Chung CM, Leu HB et al (2014) Diabetes mellitus and the risk of alzheimer’s disease: a nationwide population-based study. PLoS One 9:e87095
    • (2014) PLoS One , vol.9
    • Huang, C.C.1    Chung, C.M.2    Leu, H.B.3
  • 8
    • 67349085203 scopus 로고    scopus 로고
    • Uncontrolled diabetes increases the risk of alzheimer’s disease: a population-based cohort study
    • COI: 1:CAS:528:DC%2BD1MXlt1Gqtbo%3D, PID: 19280172
    • Xu WL, von Strauss E, Qiu CX, Winblad B, Fratiglioni L (2009) Uncontrolled diabetes increases the risk of alzheimer’s disease: a population-based cohort study. Diabetologia 52:1031–1039
    • (2009) Diabetologia , vol.52 , pp. 1031-1039
    • Xu, W.L.1    von Strauss, E.2    Qiu, C.X.3    Winblad, B.4    Fratiglioni, L.5
  • 9
    • 84895430950 scopus 로고    scopus 로고
    • Midlife type 2 diabetes and poor glycemic control as risk factors for cognitive decline in early old age: a post hoc analysis of the Whitehall cohort study
    • PID: 24622753
    • Tuligenga RH, Dugravot A, Tabák AG et al (2014) Midlife type 2 diabetes and poor glycemic control as risk factors for cognitive decline in early old age: a post hoc analysis of the Whitehall cohort study. Lancet Diabetes Endocrinol 2:228–235
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 228-235
    • Tuligenga, R.H.1    Dugravot, A.2    Tabák, A.G.3
  • 10
    • 63249111096 scopus 로고    scopus 로고
    • Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study
    • COI: 1:CAS:528:DC%2BD1MXptVChtw%3D%3D, PID: 18952836
    • Xu W, Qiu C, Gatz M, Pedersen NL, Johansson B, Fratiglioni L (2009) Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study. Diabetes 58:71–77
    • (2009) Diabetes , vol.58 , pp. 71-77
    • Xu, W.1    Qiu, C.2    Gatz, M.3    Pedersen, N.L.4    Johansson, B.5    Fratiglioni, L.6
  • 11
    • 84885980196 scopus 로고    scopus 로고
    • History of medically treated diabetes and risk of alzheimer disease in a nationwide case-control study
    • PID: 23340883
    • Tolppanen AM, Lavikainen P, Solomon A et al (2013) History of medically treated diabetes and risk of alzheimer disease in a nationwide case-control study. Diabetes Care 36:2015–2019
    • (2013) Diabetes Care , vol.36 , pp. 2015-2019
    • Tolppanen, A.M.1    Lavikainen, P.2    Solomon, A.3
  • 12
    • 84903136322 scopus 로고    scopus 로고
    • Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to alzheimer disease
    • PID: 24931033
    • De Felice FG, Ferreira ST (2014) Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to alzheimer disease. Diabetes 63:2262–2272
    • (2014) Diabetes , vol.63 , pp. 2262-2272
    • De Felice, F.G.1    Ferreira, S.T.2
  • 14
    • 64749114159 scopus 로고    scopus 로고
    • Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BD1MXksVyks7Y%3D, PID: 19366776
    • Whitmer RA, Kater AJ, Yaffe K, Quesenberry CP, Selby JV (2009) Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA 301:1565–1572
    • (2009) JAMA , vol.301 , pp. 1565-1572
    • Whitmer, R.A.1    Kater, A.J.2    Yaffe, K.3    Quesenberry, C.P.4    Selby, J.V.5
  • 15
    • 84893085179 scopus 로고    scopus 로고
    • Severe hypoglycemia and cognitive decline in older people with type 2 diabetes: the Edinburgh type 2 diabetes study
    • COI: 1:CAS:528:DC%2BC2cXks1Cqurk%3D, PID: 24103900
    • Feinkohl I, Aung PP, Keller M et al (2014) Severe hypoglycemia and cognitive decline in older people with type 2 diabetes: the Edinburgh type 2 diabetes study. Diabetes Care 37:507–515
    • (2014) Diabetes Care , vol.37 , pp. 507-515
    • Feinkohl, I.1    Aung, P.P.2    Keller, M.3
  • 16
    • 84940916872 scopus 로고    scopus 로고
    • Case-finding for cognitive impairment among people with type 2 diabetes in primary care using test your memory and self-administered gerocognitive examination questionnaires: the Cog-ID study
    • COI: 1:STN:280:DC%2BC28%2FoslSgtA%3D%3D, PID: 26234771
    • Koekkoek PS, Janssen J, Kooistra M et al (2016) Case-finding for cognitive impairment among people with type 2 diabetes in primary care using test your memory and self-administered gerocognitive examination questionnaires: the Cog-ID study. Diabet Med 33:812–819
    • (2016) Diabet Med , vol.33 , pp. 812-819
    • Koekkoek, P.S.1    Janssen, J.2    Kooistra, M.3
  • 17
    • 84885952847 scopus 로고    scopus 로고
    • Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study
    • PID: 24622366
    • Exalto LG, Biessels GJ, Karter AJ et al (2013) Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study. Lancet Diabetes Endocrinol 1:183–190
    • (2013) Lancet Diabetes Endocrinol , vol.1 , pp. 183-190
    • Exalto, L.G.1    Biessels, G.J.2    Karter, A.J.3
  • 18
    • 84885216130 scopus 로고    scopus 로고
    • Association of depression with accelerated cognitive decline among patients with type 2 diabetes in the ACCORD-MIND trial
    • PID: 23945905
    • Sullivan MD, Katon WJ, Lovato LC et al (2013) Association of depression with accelerated cognitive decline among patients with type 2 diabetes in the ACCORD-MIND trial. JAMA Psychiatry 70:1041–1047
    • (2013) JAMA Psychiatry , vol.70 , pp. 1041-1047
    • Sullivan, M.D.1    Katon, W.J.2    Lovato, L.C.3
  • 19
    • 84903220594 scopus 로고    scopus 로고
    • Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI?
    • PID: 24931032
    • Biessels GJ, Reijmer YD (2014) Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI? Diabetes 63:2244–2252
    • (2014) Diabetes , vol.63 , pp. 2244-2252
    • Biessels, G.J.1    Reijmer, Y.D.2
  • 20
    • 84906794839 scopus 로고    scopus 로고
    • Global brain atrophy but not hippocampal atrophy is related to type 2 diabetes
    • PID: 24958596
    • Wisse LE, de Bresser J, Geerlings MI et al (2014) Global brain atrophy but not hippocampal atrophy is related to type 2 diabetes. J Neurol Sci 344:32–36
    • (2014) J Neurol Sci , vol.344 , pp. 32-36
    • Wisse, L.E.1    de Bresser, J.2    Geerlings, M.I.3
  • 21
    • 84945483458 scopus 로고    scopus 로고
    • Structural imaging of hippocampal subfields in healthy aging and alzheimer’s disease
    • PID: 26306871
    • De Flores R, La Joie R, Chételat G (2015) Structural imaging of hippocampal subfields in healthy aging and alzheimer’s disease. Neuroscience 309:29–50
    • (2015) Neuroscience , vol.309 , pp. 29-50
    • De Flores, R.1    La Joie, R.2    Chételat, G.3
  • 22
    • 84944714835 scopus 로고    scopus 로고
    • Hippocampal insulin resistance and cognitive dysfunction
    • COI: 1:CAS:528:DC%2BC2MXhs1eksr7P, PID: 26462756
    • Biessels GJ, Reagan LP (2015) Hippocampal insulin resistance and cognitive dysfunction. Nat Rev Neurosci 16:660–671
    • (2015) Nat Rev Neurosci , vol.16 , pp. 660-671
    • Biessels, G.J.1    Reagan, L.P.2
  • 23
    • 84873817577 scopus 로고    scopus 로고
    • Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults
    • COI: 1:CAS:528:DC%2BC3sXislyisLo%3D, PID: 23069842
    • Willette AA, Xu G, Johnson SC et al (2013) Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 36:443–449
    • (2013) Diabetes Care , vol.36 , pp. 443-449
    • Willette, A.A.1    Xu, G.2    Johnson, S.C.3
  • 24
    • 84946127342 scopus 로고    scopus 로고
    • Analysis of the relationships between type 2 diabetes status, glycemic control, and neuroimaging measures in the diabetes heart study mind
    • COI: 1:CAS:528:DC%2BC2MXhslyntrrM, PID: 26525870
    • Raffield LM, Cox AJ, Freedman BI et al (2016) Analysis of the relationships between type 2 diabetes status, glycemic control, and neuroimaging measures in the diabetes heart study mind. Acta Diabetol 53:439–447
    • (2016) Acta Diabetol , vol.53 , pp. 439-447
    • Raffield, L.M.1    Cox, A.J.2    Freedman, B.I.3
  • 25
    • 84911874575 scopus 로고    scopus 로고
    • The cross-sectional and longitudinal associations of diabetic retinopathy with cognitive function and brain MRI findings: the action to control cardiovascular risk in diabetes (ACCORD) trial
    • PID: 25193529
    • Hugenschmidt CE, Lovato JF, Ambrosius WT et al (2014) The cross-sectional and longitudinal associations of diabetic retinopathy with cognitive function and brain MRI findings: the action to control cardiovascular risk in diabetes (ACCORD) trial. Diabetes Care 37:3244–3252
    • (2014) Diabetes Care , vol.37 , pp. 3244-3252
    • Hugenschmidt, C.E.1    Lovato, J.F.2    Ambrosius, W.T.3
  • 27
    • 77958021269 scopus 로고    scopus 로고
    • Microvascular determinants of cognitive decline and brain volume change in elderly patients with type 2 diabetes
    • PID: 20962529
    • de Bresser J, Reijmer YD, van der Exalto E et al (2010) Microvascular determinants of cognitive decline and brain volume change in elderly patients with type 2 diabetes. Dement Geriatr Cogn Disord 30:381–386
    • (2010) Dement Geriatr Cogn Disord , vol.30 , pp. 381-386
    • de Bresser, J.1    Reijmer, Y.D.2    van der Exalto, E.3
  • 28
    • 84887302167 scopus 로고    scopus 로고
    • Albuminuria and cognitive decline in people with diabetes and normal renal function
    • PID: 23990163
    • Barzilay JI, Lovato JF, Murray AM et al (2013) Albuminuria and cognitive decline in people with diabetes and normal renal function. Clin J Am Soc Nephrol 8:1907–1914
    • (2013) Clin J Am Soc Nephrol , vol.8 , pp. 1907-1914
    • Barzilay, J.I.1    Lovato, J.F.2    Murray, A.M.3
  • 29
    • 84871694414 scopus 로고    scopus 로고
    • Hypoglycaemic episodes and risk of dementia in diabetes mellitus: 7-year follow-up study
    • PID: 23003116
    • Lin CH, Sheu WHH (2013) Hypoglycaemic episodes and risk of dementia in diabetes mellitus: 7-year follow-up study. J Intern Med 273:102–110
    • (2013) J Intern Med , vol.273 , pp. 102-110
    • Lin, C.H.1    Sheu, W.H.H.2
  • 30
    • 84957057093 scopus 로고    scopus 로고
    • Bi-directional interaction between hypoglycaemia and cognitive impairment in elderly patients treated with glucose-lowering agents: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC28Xhs1Kiu7w%3D, PID: 26446922
    • Mattishent K, Loke YK (2016) Bi-directional interaction between hypoglycaemia and cognitive impairment in elderly patients treated with glucose-lowering agents: a systematic review and meta-analysis. Diabetes Obes Metab 18(2):135–141
    • (2016) Diabetes Obes Metab , vol.18 , Issue.2 , pp. 135-141
    • Mattishent, K.1    Loke, Y.K.2
  • 31
    • 84911889618 scopus 로고    scopus 로고
    • Effect of hypoglycemia on brain structure in people with type 2 diabetes: epidemiological analysis of the ACCORD-MIND MRI trial
    • COI: 1:CAS:528:DC%2BC2cXitFansbvP, PID: 25267796
    • Zhang Z, Lovato J, Battapady H et al (2014) Effect of hypoglycemia on brain structure in people with type 2 diabetes: epidemiological analysis of the ACCORD-MIND MRI trial. Diabetes Care 37(12):3279–3285
    • (2014) Diabetes Care , vol.37 , Issue.12 , pp. 3279-3285
    • Zhang, Z.1    Lovato, J.2    Battapady, H.3
  • 32
    • 78650752971 scopus 로고    scopus 로고
    • Relationship between daily acute glucose fluctuations and cognitive performance among type 2 diabetic patients
    • PID: 20573753
    • Rizzo MR, Marfella R, Barbieri M et al (2010) Relationship between daily acute glucose fluctuations and cognitive performance among type 2 diabetic patients. Diabetes Care 33:2169–2174
    • (2010) Diabetes Care , vol.33 , pp. 2169-2174
    • Rizzo, M.R.1    Marfella, R.2    Barbieri, M.3
  • 33
    • 84906246754 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors have protective effect on cognitive impairment in aged diabetic patients with mild cognitive impairment
    • PID: 24671867
    • Rizzo MR, Barbieri M, Boccardi V, Angellotti E, Marfella R, Paolisso G (2014) Dipeptidyl peptidase-4 inhibitors have protective effect on cognitive impairment in aged diabetic patients with mild cognitive impairment. J Gerontol A Biol Sci Med Sci 69:1122–1131
    • (2014) J Gerontol A Biol Sci Med Sci , vol.69 , pp. 1122-1131
    • Rizzo, M.R.1    Barbieri, M.2    Boccardi, V.3    Angellotti, E.4    Marfella, R.5    Paolisso, G.6
  • 34
    • 84883625197 scopus 로고    scopus 로고
    • Evaluation of retinal nerve fiber layer and ganglion cell layer thickness in alzheimer’s disease using spectral-domain optical coherence tomography
    • Marciani E, Pomati S, Ramolfo P et al (2013) Evaluation of retinal nerve fiber layer and ganglion cell layer thickness in alzheimer’s disease using spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci 54:5953–5958
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 5953-5958
    • Marciani, E.1    Pomati, S.2    Ramolfo, P.3
  • 36
    • 84890989082 scopus 로고    scopus 로고
    • Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives
    • PID: 24183659
    • Simó R, Hernández C, European consortium for the early treatment of diabetic retinopathy (EUROCONDOR) (2014) Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives. Trends Endocrinol Metab 25:23–33
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 23-33
    • Simó, R.1    Hernández, C.2
  • 37
    • 84987670067 scopus 로고    scopus 로고
    • Vision related quality of life in patients with type 2 diabetes in the EUROCONDOR trial
    • PID: 27628581
    • Trento M, Durando O, Lavecchia S et al (2016) Vision related quality of life in patients with type 2 diabetes in the EUROCONDOR trial. Endocrine. doi:10.1007/s12020-016-1097-0
    • (2016) Endocrine
    • Trento, M.1    Durando, O.2    Lavecchia, S.3
  • 38
    • 85019387547 scopus 로고    scopus 로고
    • Cognitive function may be a predictor of retinopathy progression in patients with type 2 diabetes
    • PID: 27716894
    • Trento M, Charrier L, Salassa M et al (2016) Cognitive function may be a predictor of retinopathy progression in patients with type 2 diabetes. Eur J Ophthalmol. doi:10.5301/ejo.5000885
    • (2016) Eur J Ophthalmol
    • Trento, M.1    Charrier, L.2    Salassa, M.3
  • 39
    • 61449203273 scopus 로고    scopus 로고
    • Clinical practice recommendations
    • American Diabetes Association (2013) Clinical practice recommendations. Diabetes Care 36(Suppl 1):S3
    • (2013) Diabetes Care , vol.36 , pp. S3
  • 40
    • 84937814788 scopus 로고    scopus 로고
    • The social burden of hypoglycemia in the elderly
    • COI: 1:CAS:528:DC%2BC2MXislGktr4%3D, PID: 25663036
    • Nicolucci A, Pintaudi B, Rossi MC et al (2015) The social burden of hypoglycemia in the elderly. Acta Diabetol 52:677–685
    • (2015) Acta Diabetol , vol.52 , pp. 677-685
    • Nicolucci, A.1    Pintaudi, B.2    Rossi, M.C.3
  • 41
    • 84896920228 scopus 로고    scopus 로고
    • Insulin, incretins and other growth factors as potential novel treatments for alzheimer’s and parkinson’s diseases
    • PID: 24646283
    • Hölscher C (2014) Insulin, incretins and other growth factors as potential novel treatments for alzheimer’s and parkinson’s diseases. Biochem Soc Trans 42:593–599
    • (2014) Biochem Soc Trans , vol.42 , pp. 593-599
    • Hölscher, C.1
  • 42
    • 84962147366 scopus 로고    scopus 로고
    • Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes
    • PID: 26384381
    • Hernández C, Bogdanov P, Corraliza L et al (2016) Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes. Diabetes 65:172–187
    • (2016) Diabetes , vol.65 , pp. 172-187
    • Hernández, C.1    Bogdanov, P.2    Corraliza, L.3
  • 43
    • 84937733175 scopus 로고    scopus 로고
    • Effect of pioglitazone medication on the incidence of dementia
    • COI: 1:CAS:528:DC%2BC2MXht1KmsLbJ, PID: 25974006
    • Heneka MT, Fink A, Doblhammer G (2015) Effect of pioglitazone medication on the incidence of dementia. Ann Neurol 78(2):284–294
    • (2015) Ann Neurol , vol.78 , Issue.2 , pp. 284-294
    • Heneka, M.T.1    Fink, A.2    Doblhammer, G.3
  • 44
    • 85002213759 scopus 로고    scopus 로고
    • Pioglitazone for the treatment of alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC28XitVSmt7nO, PID: 27885860
    • Galimberti D, Scarpini E (2017) Pioglitazone for the treatment of alzheimer’s disease. Expert Opin Investig Drugs 26(1):97–101
    • (2017) Expert Opin Investig Drugs , vol.26 , Issue.1 , pp. 97-101
    • Galimberti, D.1    Scarpini, E.2
  • 45
    • 33745266146 scopus 로고    scopus 로고
    • Rosiglitazone in alzheimer’s disease study group
    • COI: 1:CAS:528:DC%2BD28Xnt1agu7k%3D, PID: 16446752
    • Risner ME, Saunders AM, Altman JF et al (2006) Rosiglitazone in alzheimer’s disease study group. Pharmacogenomics J. 6(4):246–254
    • (2006) Pharmacogenomics J. , vol.6 , Issue.4 , pp. 246-254
    • Risner, M.E.1    Saunders, A.M.2    Altman, J.F.3
  • 46
    • 84973428782 scopus 로고    scopus 로고
    • Targeting insulin signaling for the treatment of alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC2MXhslGksbjK, PID: 26268336
    • Chen Y, Zhang J, Zhang B, Gong CX (2016) Targeting insulin signaling for the treatment of alzheimer’s disease. Curr Top Med Chem 16:485–492
    • (2016) Curr Top Med Chem , vol.16 , pp. 485-492
    • Chen, Y.1    Zhang, J.2    Zhang, B.3    Gong, C.X.4
  • 47
    • 84922666525 scopus 로고    scopus 로고
    • Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage alzheimer’s disease dementia
    • COI: 1:CAS:528:DC%2BC2MXitlWrsrc%3D
    • Claxton A, Baker LD, Hanson A et al (2015) Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage alzheimer’s disease dementia. J Alzheimer Dis 44:897–906
    • (2015) J Alzheimer Dis , vol.44 , pp. 897-906
    • Claxton, A.1    Baker, L.D.2    Hanson, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.