Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

PLoS Biology

Volumn 14, Issue 9, 2016, Pages

  Gupta, Varun K ^a,b   Pech, Ulrike ^c   Bhukel, Anuradha ^a,b   Fulterer, Andreas ^a,b   Ender, Anatoli ^a   Mauermann, Stephan F ^a,b   Andlauer, Till F M ^d   Antwi Adjei, Emmanuel ^a   Beuschel, Christine ^a   Thriene, Kerstin ^e   Maglione, Marta ^a,b   Quentin, Christine ^a,b   Bushow, René ^f   Schwärzel, Martin ^a   Mielke, Thorsten ^f   Madeo, Frank ^g,h   Dengjel, Joern ^e   Fiala, André ^c   Sigrist, Stephan J ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

^f MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^g UNIVERSITY OF GRAZ   (Austria)

^h BIOTECHMED GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BRUCHPILOT PROTEIN; DROSOPHILA PROTEIN; GREEN FLUORESCENT PROTEIN; RIM BINDING PROTEIN; SPERMIDINE; SYNAPSIN; SYNAPTOBREVIN; SYNAPTOPHLUORIN; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ADULT; AGE DEPENDENT MEMORY IMPAIRMENT; AGED; AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRP GENE; CALCIUM SIGNALING; CELL STRUCTURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DROSOPHILA MELANOGASTER; DROSOPHILA STRAIN; ELECTRON MICROSCOPY; FEEDING; FEMALE; GENE; GENE DOSAGE; HOMEOSTASIS; KENYON CELL; MEMORY DISORDER; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; OLFACTORY MEMORY; PRESYNAPTIC ACTIVE ZONE; PROJECTION NEURON; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; ULTRASTRUCTURE;

EID: 84991761763     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002563     Document Type: Article

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