A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice

Nature Medicine

Volumn 23, Issue 6, 2017, Pages 782-787

  Bilkei Gorzo, Andras ^a   Albayram, Onder ^a   Draffehn, Astrid ^a   Michel, Kerstin ^a   Piyanova, Anastasia ^a   Oppenheimer, Hannah ^b   Dvir Ginzberg, Mona ^b   Rácz, Ildiko ^a   Ulas, Thomas ^a   Imbeault, Sophie ^a   Bab, Itai ^b   Schultze, Joachim L ^a   Zimmer, Andreas ^a  

^a UNIVERSITY OF BONN   (Germany)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPSIN I; SYNAPTOPHYSIN; TETRAHYDROCANNABINOL; DRONABINOL; TRANSCRIPTOME;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; GENE ONTOLOGY; GENETIC TRANSCRIPTION; GLUTAMATERGIC SYNAPSE; HIPPOCAMPUS; HISTONE ACETYLATION; IMMUNOHISTOCHEMISTRY; LOW DRUG DOSE; MEMORY; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPINE; SYNAPSE; ACETYLATION; ANIMAL; ANIMAL BEHAVIOR; COGNITIVE AGING; CYTOLOGY; DENDRITIC SPINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HISTONE CODE; KNOCKOUT MOUSE; LONG TERM MEMORY; METABOLISM; PATHOLOGY; PSYCHOLOGY; SPATIAL MEMORY;

ACETYLATION; AGING; ANIMALS; BEHAVIOR, ANIMAL; COGNITION; COGNITIVE AGING; COGNITIVE DYSFUNCTION; DENDRITIC SPINES; DRONABINOL; ENDOCANNABINOIDS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HISTONE CODE; MEMORY, LONG-TERM; MICE; MICE, KNOCKOUT; RECEPTOR, CANNABINOID, CB1; SPATIAL LEARNING; SPATIAL MEMORY; TRANSCRIPTOME;

EID: 85020264484     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4311     Document Type: Article

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