High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase Bo-glc nacylation

Journal of Biological Chemistry

Volumn 293, Issue 29, 2018, Pages 11388-11400

  De Barros Peruchetti, Diogo ^b   Silva Aguiar, Rodrigo Pacheco ^b   Siqueira, Gabriela Marques ^b   Dias, Wagner Barbosa ^b   Caruso Neves, Celso ^a,b  

^a Instituto Nacional de Ciencia e Tecnologia em Entomologia Molecular   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CYTOLOGY; ENZYMES; GLUCOSE; MAMMALS; MOLECULAR BIOLOGY; PHOSPHORYLATION;

BIOSYNTHETIC PATHWAY; GLYCOGEN SYNTHASE KINASE-3; INHIBITORY EFFECT; INTRACELLULAR PROTEINS; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MOLECULAR MECHANISM; SPECIFIC SUBSTRATES; TUBEROUS SCLEROSIS;

CELLS;

ALBUMIN; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; HEXOSAMINE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEGALIN; N ACETYLGLUCOSAMINE; PROTEIN KINASE B; S6 KINASE; SERINE; SODIUM GLUCOSE COTRANSPORTER; THREONINE; TUBERIN; BOVINE SERUM ALBUMIN;

ACYLATION; ALBUMINURIA; ARTICLE; CARBOHYDRATE SYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; HYPERGLYCEMIA; INCUBATION TIME; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; LLC PK1 CELL LINE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BOVINE; CELL LINE; CYTOLOGY; DIABETIC NEPHROPATHY; METABOLISM; PIG;

ACYLATION; ANIMALS; CATTLE; CELL LINE; DIABETIC NEPHROPATHIES; ENDOCYTOSIS; GLUCOSE; HYPERGLYCEMIA; KIDNEY TUBULES, PROXIMAL; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; PROTO-ONCOGENE PROTEINS C-AKT; SERUM ALBUMIN, BOVINE; SUS SCROFA;

EID: 85050390822     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.RA117.001337     Document Type: Article

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