Cadmium impairs albumin reabsorption by down-regulating megalin and clc5 channels in renal proximal tubule cells

Environmental Health Perspectives

Volumn 118, Issue 11, 2010, Pages 1551-1556

  Gena, Patrizia ^a,b   Calamita, Giuseppe ^b   Guggino, William B ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Albuminuria; Cadmium; Clc5; Heavy metals; Megalin; Nephrotoxicity; Renal proximal tubules

Indexed keywords

ALBUMIN; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CADMIUM CHLORIDE; CHLORIDE CHANNEL; CHLORIDE CHANNEL 5; CYCLOHEXIMIDE; MEGALIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ALBUMINURIA; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; GENE EXPRESSION; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE CELL; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; TOXICITY TESTING;

ALBUMINS; ALBUMINURIA; ANIMALS; CADMIUM; CELLS, CULTURED; CHLORIDE CHANNELS; DOWN-REGULATION; ENVIRONMENTAL POLLUTANTS; KIDNEY TUBULES, PROXIMAL; LDL-RECEPTOR RELATED PROTEIN 2; RNA, MESSENGER;

SUIDAE;

EID: 78149302550     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0901874     Document Type: Article

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