-
1
-
-
0021280147
-
Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes
-
Torres CR, Hart GW. Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc. J Biol Chem (1984) 259(5):3308-17.
-
(1984)
Evidence for O-linked GlcNAc. J Biol Chem
, vol.259
, Issue.5
, pp. 3308-3317
-
-
Torres, C.R.1
Hart, G.W.2
-
2
-
-
34247583996
-
Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins
-
doi:10.1038/nature05815
-
Hart GW, Housley MP, Slawson C. Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature (2007) 446(7139):1017-22. doi:10.1038/nature05815
-
(2007)
Nature
, vol.446
, Issue.7139
, pp. 1017-1022
-
-
Hart, G.W.1
Housley, M.P.2
Slawson, C.3
-
3
-
-
0842347416
-
Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability
-
doi:10.1128/MCB.24.4.1680-1690.2004
-
O'Donnell N, Zachara NE, Hart GW, Marth JD. Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability. Mol Cell Biol (2004) 24(4):1680-90. doi:10.1128/MCB.24.4.1680-1690.2004
-
(2004)
Mol Cell Biol
, vol.24
, Issue.4
, pp. 1680-1690
-
-
O'Donnell, N.1
Zachara, N.E.2
Hart, G.W.3
Marth, J.D.4
-
4
-
-
77949332132
-
Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-linked beta-N-acetylglucosamine in 3T3-L1 adipocytes
-
doi:10.1074/jbc.M109.077818
-
Whelan SA, Dias WB, Thiruneelakantapillai L, Lane MD, Hart GW. Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-linked beta-N-acetylglucosamine in 3T3-L1 adipocytes. J Biol Chem (2010) 285(8):5204-11. doi:10.1074/jbc.M109.077818
-
(2010)
J Biol Chem
, vol.285
, Issue.8
, pp. 5204-5211
-
-
Whelan, S.A.1
Dias, W.B.2
Thiruneelakantapillai, L.3
Lane, M.D.4
Hart, G.W.5
-
5
-
-
57349187712
-
A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin
-
doi:10.1091/mbc.E07-11-1146
-
Slawson C, Lakshmanan T, Knapp S, Hart GW. A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell (2008) 19(10):4130-40. doi:10.1091/mbc.E07-11-1146
-
(2008)
Mol Biol Cell
, vol.19
, Issue.10
, pp. 4130-4140
-
-
Slawson, C.1
Lakshmanan, T.2
Knapp, S.3
Hart, G.W.4
-
6
-
-
69249155637
-
Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification
-
21327-37, doi:10.1074/jbc.M109.007310
-
Dias WB, Cheung WD, Wang Z, Hart GW. Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification. J Biol Chem (2009) 284(32):21327-37. doi:10.1074/jbc.M109.007310
-
(2009)
J Biol Chem
, vol.284
, Issue.32
-
-
Dias, W.B.1
Cheung, W.D.2
Wang, Z.3
Hart, G.W.4
-
7
-
-
84861658628
-
O-GlcNAcylation of kinases
-
doi:10.1016/j.bbrc.2012.04.124
-
Dias WB, Cheung WD, Hart GW. O-GlcNAcylation of kinases. Biochem Biophys Res Commun (2012) 422(2):224-8. doi:10.1016/j.bbrc.2012.04.124
-
(2012)
Biochem Biophys Res Commun
, vol.422
, Issue.2
, pp. 224-228
-
-
Dias, W.B.1
Cheung, W.D.2
Hart, G.W.3
-
8
-
-
84891703312
-
Chemical tools to probe cellular O-GlcNAc signalling
-
doi:10.1042/BJ20131081
-
Ostrowski A, von Aalten DM. Chemical tools to probe cellular O-GlcNAc signalling. Biochem J (2013) 456(1):1-12. doi:10.1042/BJ20131081
-
(2013)
Biochem J
, vol.456
, Issue.1
, pp. 1-12
-
-
Ostrowski, A.1
von Aalten, D.M.2
-
9
-
-
33644873810
-
Hexosamines, insulin resistance, and the complications of diabetes: current status
-
doi:10.1152/ajpendo.00329.2005
-
Buse MG. Hexosamines, insulin resistance, and the complications of diabetes: current status. Am J Physiol Endocrinol Metab (2006) 290(1):E1-8. doi:10.1152/ajpendo.00329.2005
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
, Issue.1
-
-
Buse, M.G.1
-
10
-
-
0033527739
-
Regulation of a cytosolic and nuclear O-GlcNAc transferase
-
32015-22, doi:10.1074/jbc.274.45.32015
-
Kreppel LK, Hart GW. Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. J Biol Chem (1999) 274(45):32015-22. doi:10.1074/jbc.274.45.32015
-
(1999)
Role of the tetratricopeptide repeats. J Biol Chem
, vol.274
, Issue.45
-
-
Kreppel, L.K.1
Hart, G.W.2
-
11
-
-
35348866703
-
O-GlcNAc modification in diabetes and Alzheimer's disease
-
doi:10.1039/b704905f
-
Dias WB, Hart GW. O-GlcNAc modification in diabetes and Alzheimer's disease. Mol Biosyst (2007) 3(11):766-72. doi:10.1039/b704905f
-
(2007)
Mol Biosyst
, vol.3
, Issue.11
, pp. 766-772
-
-
Dias, W.B.1
Hart, G.W.2
-
12
-
-
80052068559
-
O-GlcNAc signalling: implications for cancer cell biology
-
doi:10.1038/nrc3114
-
Slawson C, Hart GW. O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer (2011) 11(9):678-84. doi:10.1038/nrc3114
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.9
, pp. 678-684
-
-
Slawson, C.1
Hart, G.W.2
-
13
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg O. On respiratory impairment in cancer cells. Science (1956) 124(3215):269-70.
-
(1956)
Science
, vol.124
, Issue.3215
, pp. 269-270
-
-
Warburg, O.1
-
14
-
-
79961152254
-
GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker
-
doi:10.1590/S1807-59322011000600008
-
Carvalho KC, Cunha IW, Rocha RM, Ayala FR, Cajaíba MM, Begnami MD, et al. GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker. Clinics (Sao Paulo) (2011) 66(6):965-72. doi:10.1590/S1807-59322011000600008
-
(2011)
Clinics (Sao Paulo)
, vol.66
, Issue.6
, pp. 965-972
-
-
Carvalho, K.C.1
Cunha, I.W.2
Rocha, R.M.3
Ayala, F.R.4
Cajaíba, M.M.5
Begnami, M.D.6
-
15
-
-
0036717382
-
Molecular imaging of cancer with positron emission tomography
-
doi:10.1038/nrc882
-
Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer (2002) 2(9):683-93. doi:10.1038/nrc882
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.9
, pp. 683-693
-
-
Gambhir, S.S.1
-
16
-
-
84882607514
-
O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
-
doi:10.1158/0008-5472.CAN-13-0549
-
Itkonen HM, Minner S, Guldvik IJ, Sandmann MJ, Tsourlakis MC, Berge V, et al. O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells. Cancer Res (2013) 73(16):5277-87. doi:10.1158/0008-5472.CAN-13-0549
-
(2013)
Cancer Res
, vol.73
, Issue.16
, pp. 5277-5287
-
-
Itkonen, H.M.1
Minner, S.2
Guldvik, I.J.3
Sandmann, M.J.4
Tsourlakis, M.C.5
Berge, V.6
-
17
-
-
84876084149
-
Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells
-
doi:10.1371/journal.pone.0060471
-
Alisson-Silva F, Freire-de-Lima L, Donadio JL, Lucena MC, Penha L, Sá-Diniz JN, et al. Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells. PLoS One (2013) 8(4):e60471. doi:10.1371/journal.pone.0060471
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Alisson-Silva, F.1
Freire-de-Lima, L.2
Donadio, J.L.3
Lucena, M.C.4
Penha, L.5
Sá-Diniz, J.N.6
-
18
-
-
70350685770
-
Adaptive regulation at the cell surface by N-glycosylation
-
doi:10.1111/j.16000854.2009.00981.x
-
Dennis JW, Lau KS, Demetriou M, Nabi IR. Adaptive regulation at the cell surface by N-glycosylation. Traffic (2009) 10(11):1569-78. doi:10.1111/j.16000854.2009.00981.x
-
(2009)
Traffic
, vol.10
, Issue.11
, pp. 1569-1578
-
-
Dennis, J.W.1
Lau, K.S.2
Demetriou, M.3
Nabi, I.R.4
-
20
-
-
84885315910
-
O-GlcNAc in cancer biology
-
doi:10.1007/s00726-013-1543-8
-
Ma Z, Vosseller K. O-GlcNAc in cancer biology. Amino Acids (2013) 45(4):719-33. doi:10.1007/s00726-013-1543-8
-
(2013)
Amino Acids
, vol.45
, Issue.4
, pp. 719-733
-
-
Ma, Z.1
Vosseller, K.2
-
21
-
-
77955401818
-
GlcNAcylation plays an essential role in breast cancer metastasis
-
doi:10.1158/0008-5472.CAN-09-1887
-
Gu Y, Mi W, Ge Y, Liu H, Fan Q, Han C, et al. GlcNAcylation plays an essential role in breast cancer metastasis. Cancer Res (2010) 70(15):6344-51. doi:10.1158/0008-5472.CAN-09-1887
-
(2010)
Cancer Res
, vol.70
, Issue.15
, pp. 6344-6351
-
-
Gu, Y.1
Mi, W.2
Ge, Y.3
Liu, H.4
Fan, Q.5
Han, C.6
-
22
-
-
77952429792
-
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
-
doi:10.1038/onc.2010.41
-
Caldwell SA, Jackson SR, Shahriari KS, Lynch TP, Sethi G, Walker S, et al. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene (2010) 29(19):2831-42. doi:10.1038/onc.2010.41
-
(2010)
Oncogene
, vol.29
, Issue.19
, pp. 2831-2842
-
-
Caldwell, S.A.1
Jackson, S.R.2
Shahriari, K.S.3
Lynch, T.P.4
Sethi, G.5
Walker, S.6
-
23
-
-
84880627384
-
Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer
-
doi:10.1002/pmic.201200126
-
Champattanachai V, Netsirisawan P, Chaiyawat P, Phueaouan T, Charoenwattanasatien R, Chokchaichamnankit D, et al. Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer. Proteomics (2013) 13:2088-99. doi:10.1002/pmic.201200126
-
(2013)
Proteomics
, vol.13
, pp. 2088-2099
-
-
Champattanachai, V.1
Netsirisawan, P.2
Chaiyawat, P.3
Phueaouan, T.4
Charoenwattanasatien, R.5
Chokchaichamnankit, D.6
-
24
-
-
84858148966
-
Gene expression of O-GlcNAc cycling enzymes in human breast cancers
-
doi:10.1007/s10238-011-0138-5
-
Krzeslak A, Forma E, Bernaciak M, Romanowicz H, Brys M. Gene expression of O-GlcNAc cycling enzymes in human breast cancers. Clin Exp Med (2012) 12(1):61-5. doi:10.1007/s10238-011-0138-5
-
(2012)
Clin Exp Med
, vol.12
, Issue.1
, pp. 61-65
-
-
Krzeslak, A.1
Forma, E.2
Bernaciak, M.3
Romanowicz, H.4
Brys, M.5
-
25
-
-
0035964998
-
Increased N-acetyl-ß-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins
-
doi:10.1016/S0925-4439(01)00067-9
-
Slawson C, Pidala J, Potter R. Increased N-acetyl-ß-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. Biochim Biophys Acta (2001) 1537(2):147-57. doi:10.1016/S0925-4439(01)00067-9
-
(2001)
Biochim Biophys Acta
, vol.1537
, Issue.2
, pp. 147-157
-
-
Slawson, C.1
Pidala, J.2
Potter, R.3
-
26
-
-
84859484538
-
Critical role of O-Linked ß-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis
-
11070-81, doi:10.1074/jbc.M111.302547
-
Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked ß-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. J Biol Chem (2012) 287:11070-81. doi:10.1074/jbc.M111.302547
-
(2012)
J Biol Chem
, vol.287
-
-
Lynch, T.P.1
Ferrer, C.M.2
Jackson, S.R.3
Shahriari, K.S.4
Vosseller, K.5
Reginato, M.J.6
-
27
-
-
84894076239
-
Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients
-
doi:10.1038/pcan.2013.56
-
Kamigaito T, Okaneya T, Kawakubo M, Shimojo H, Nishizawa O, Nakayama J. Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients. Prostate Cancer Prostatic Dis (2013) 17(1):18-22. doi:10.1038/pcan.2013.56
-
(2013)
Prostate Cancer Prostatic Dis
, vol.17
, Issue.1
, pp. 18-22
-
-
Kamigaito, T.1
Okaneya, T.2
Kawakubo, M.3
Shimojo, H.4
Nishizawa, O.5
Nakayama, J.6
-
28
-
-
79751525993
-
O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy
-
doi:10.1016/j.bbadis.2011.01.009
-
Mi W, Gu Y, Han C, Liu H, Fan Q, Zhang X, et al. O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy. Biochim Biophys Acta (2011) 1812(4):514-9. doi:10.1016/j.bbadis.2011.01.009
-
(2011)
Biochim Biophys Acta
, vol.1812
, Issue.4
, pp. 514-519
-
-
Mi, W.1
Gu, Y.2
Han, C.3
Liu, H.4
Fan, Q.5
Zhang, X.6
-
29
-
-
84892396362
-
Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer
-
doi:10.3892/or.2013.2794
-
Phueaouan T, Chaiyawat P, Netsirisawan P, Chokchaichamnankit D, Punyarit P, Srisomsap C, et al. Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer. Oncol Rep (2013) 30(6):2929-36. doi:10.3892/or.2013.2794
-
(2013)
Oncol Rep
, vol.30
, Issue.6
, pp. 2929-2936
-
-
Phueaouan, T.1
Chaiyawat, P.2
Netsirisawan, P.3
Chokchaichamnankit, D.4
Punyarit, P.5
Srisomsap, C.6
-
30
-
-
84865276011
-
O-linked ß-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-ß-D-glucosaminidase silencing on cell phenotype and transcriptome
-
28755-69, doi:10.1074/jbc.M112.345546
-
Yehezkel G, Cohen L, Kliger A, Manor E, Khalaila I. O-linked ß-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-ß-D-glucosaminidase silencing on cell phenotype and transcriptome. J Biol Chem (2012) 287(34):28755-69. doi:10.1074/jbc.M112.345546
-
(2012)
J Biol Chem
, vol.287
, Issue.34
-
-
Yehezkel, G.1
Cohen, L.2
Kliger, A.3
Manor, E.4
Khalaila, I.5
-
31
-
-
84863642965
-
Prediction of bladder cancer based on urinary content of MGEA5 and OGT mRNA level
-
Rozanski W, Krzeslak A, Forma E, Brys M, Blewniewski M, Wozniak P, et al. Prediction of bladder cancer based on urinary content of MGEA5 and OGT mRNA level. Clin Lab (2012) 58(5-6):579-83.
-
(2012)
Clin Lab.
, vol.58
, Issue.5-6
, pp. 579-583
-
-
Rozanski, W.1
Krzeslak, A.2
Forma, E.3
Brys, M.4
Blewniewski, M.5
Wozniak, P.6
-
32
-
-
77956422977
-
Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia
-
doi:10.1038/leu.2010.152
-
Shi Y, Tomic J, Wen F, Shaha S, Bahlo A, Harrison R, et al. Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia. Leukemia (2010) 24(9):1588-98. doi:10.1038/leu.2010.152
-
(2010)
Leukemia
, vol.24
, Issue.9
, pp. 1588-1598
-
-
Shi, Y.1
Tomic, J.2
Wen, F.3
Shaha, S.4
Bahlo, A.5
Harrison, R.6
-
33
-
-
84857126294
-
Expression of genes encoding for enzymes associated with O-GlcNAcylation in endometrial carcinomas: clinicopathologic correlations
-
Krzeslak A, Wójcik-Krowiranda K, Forma E, Bienkiewicz A, Brys M. Expression of genes encoding for enzymes associated with O-GlcNAcylation in endometrial carcinomas: clinicopathologic correlations. Ginekol Pol (2012) 83(1):22-6.
-
(2012)
Ginekol Pol
, vol.83
, Issue.1
, pp. 22-26
-
-
Krzeslak, A.1
Wójcik-Krowiranda, K.2
Forma, E.3
Bienkiewicz, A.4
Brys, M.5
-
34
-
-
84864766367
-
O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation
-
doi:10.1007/s12032-011-9912-1
-
Zhu Q, Zhou L, Yang Z, Lai M, Xie H, Wu L, et al. O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation. Med Oncol (2012) 29(2):985-93. doi:10.1007/s12032-011-9912-1
-
(2012)
Med Oncol
, vol.29
, Issue.2
, pp. 985-993
-
-
Zhu, Q.1
Zhou, L.2
Yang, Z.3
Lai, M.4
Xie, H.5
Wu, L.6
-
35
-
-
84878225772
-
Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-?B activity in pancreatic cancer cells
-
15121-30, doi:10.1074/jbc.M113.470047
-
Ma Z, Vocadlo DJ, Vosseller K. Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-?B activity in pancreatic cancer cells. J Biol Chem (2013) 288:15121-30. doi:10.1074/jbc.M113.470047
-
(2013)
J Biol Chem
, vol.288
-
-
Ma, Z.1
Vocadlo, D.J.2
Vosseller, K.3
-
36
-
-
79959924071
-
Down-regulation of ß-N-acetyl-D-glucosaminidase increases Akt1 activity in thyroid anaplastic cancer cells
-
doi:10.3892/or.2011.1333
-
Krzeslak A, Józwiak P, Lipinska A. Down-regulation of ß-N-acetyl-D-glucosaminidase increases Akt1 activity in thyroid anaplastic cancer cells. Oncol Rep (2011) 26(3):743-9. doi:10.3892/or.2011.1333
-
(2011)
Oncol Rep
, vol.26
, Issue.3
, pp. 743-749
-
-
Krzeslak, A.1
Józwiak, P.2
Lipinska, A.3
-
37
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
doi:10.1016/j.cell.2011.02.013
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell (2011) 144:646-74. doi:10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
38
-
-
61849135453
-
Tumor suppressors and cell metabolism: a recipe for cancer growth
-
doi:10.1101/gad.1756509
-
Jones RG, Thompson CB. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev (2009) 23(5):537-48. doi:10.1101/gad.1756509
-
(2009)
Genes Dev
, vol.23
, Issue.5
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
39
-
-
51349166164
-
Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins
-
11576-7, doi:10.1021/ja8030467
-
Clark PM, Dweck JF, Mason DE, Hart CR, Buck SB, Peters EC, et al. Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins. J Am Chem Soc (2008) 130:11576-7. doi:10.1021/ja8030467
-
(2008)
J Am Chem Soc
, vol.130
-
-
Clark, P.M.1
Dweck, J.F.2
Mason, D.E.3
Hart, C.R.4
Buck, S.B.5
Peters, E.C.6
-
40
-
-
84865300414
-
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism
-
doi:10.1126/science.1222278
-
Yi W, Clark PM, Mason DE, Keenan MC, Hill C, Goddard WA III, et al. Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. Science (2012) 337(6097):975-80. doi:10.1126/science.1222278
-
(2012)
Science
, vol.337
, Issue.6097
, pp. 975-980
-
-
Yi, W.1
Clark, P.M.2
Mason, D.E.3
Keenan, M.C.4
Hill, C.5
Goddard W.A, I.I.I.6
-
41
-
-
84863011452
-
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
-
doi:10.1016/j.cmet.2011.12.015
-
Yuneva MO, Fan TW, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T, et al. The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab (2012) 15:157-70. doi:10.1016/j.cmet.2011.12.015
-
(2012)
Cell Metab
, vol.15
, pp. 157-170
-
-
Yuneva, M.O.1
Fan, T.W.2
Allen, T.D.3
Higashi, R.M.4
Ferraris, D.V.5
Tsukamoto, T.6
-
42
-
-
84875894714
-
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
-
doi:10.1038/nature12040
-
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature (2013) 496:101-5. doi:10.1038/nature12040
-
(2013)
Nature
, vol.496
, pp. 101-105
-
-
Son, J.1
Lyssiotis, C.A.2
Ying, H.3
Wang, X.4
Hua, S.5
Ligorio, M.6
-
43
-
-
80052338863
-
Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia
-
e1002229, doi:10.1371/journal.pgen.1002229
-
Kung HN, Marks JR, Chi JT. Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia. PLoS Genet (2011) 7:e1002229. doi:10.1371/journal.pgen.1002229
-
(2011)
PLoS Genet
, vol.7
-
-
Kung, H.N.1
Marks, J.R.2
Chi, J.T.3
-
44
-
-
84883271078
-
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
-
doi:10.3389/fonc.2013.00038
-
Sutendra G, Michelakis ED. Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology. Front Oncol (2013) 3:38. doi:10.3389/fonc.2013.00038
-
(2013)
Front Oncol
, vol.3
, pp. 38
-
-
Sutendra, G.1
Michelakis, E.D.2
-
45
-
-
0037442984
-
Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase
-
doi:10.1242/jcs.00246
-
Love DC, Kochan J, Cathey RL, Shin SH, Hanover JA. Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci (2003) 116:647-54. doi:10.1242/jcs.00246
-
(2003)
J Cell Sci
, vol.116
, pp. 647-654
-
-
Love, D.C.1
Kochan, J.2
Cathey, R.L.3
Shin, S.H.4
Hanover, J.A.5
-
46
-
-
79954441395
-
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis
-
doi:10.1007/s00726-010-0719-8
-
Shin SH, Love DC, Hanover JA. Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis. Amino Acids (2011) 40:885-93. doi:10.1007/s00726-010-0719-8
-
(2011)
Amino Acids
, vol.40
, pp. 885-893
-
-
Shin, S.H.1
Love, D.C.2
Hanover, J.A.3
-
47
-
-
58649095123
-
Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose
-
doi:10.1074/jbc.M808518200
-
Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, TRauger SA, et al. Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem (2009) 284:547-55. doi:10.1074/jbc.M808518200
-
(2009)
J Biol Chem
, vol.284
, pp. 547-555
-
-
Hu, Y.1
Suarez, J.2
Fricovsky, E.3
Wang, H.4
Scott, B.T.5
T.Rauger, S.A.6
-
48
-
-
84901407632
-
Altering O-linked ß-N-acetylglucosamine cycling disrupts mitochondrial function
-
14719-30, doi:10.1074/jbc.M113.525790
-
Tan EP, Villar MT, E L, Lu J, Selfridge JE, Artigues A, et al. Altering O-linked ß-N-acetylglucosamine cycling disrupts mitochondrial function. J Biol Chem (2014) 289:14719-30. doi:10.1074/jbc.M113.525790
-
(2014)
J Biol Chem
, vol.289
-
-
Tan, E.P.1
Villar, M.T.2
E, L.3
Lu, J.4
Selfridge, J.E.5
Artigues, A.6
-
49
-
-
84860339096
-
Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells
-
doi:10.1016/j.bbrc.2012.03.118
-
Inoue-Yamauchi A, Oda H. Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells. Biochem Biophys Res Commun (2012) 421:81-5. doi:10.1016/j.bbrc.2012.03.118
-
(2012)
Biochem Biophys Res Commun
, vol.421
, pp. 81-85
-
-
Inoue-Yamauchi, A.1
Oda, H.2
-
50
-
-
84885181954
-
Mitochondrial dynamics regulates migration and invasion of breast cancer cells
-
doi:10.1038/onc.2012.494
-
Zhao J, Zhang J, Yu M, Xie Y, Huang Y, Wolff DW, et al. Mitochondrial dynamics regulates migration and invasion of breast cancer cells. Oncogene (2012) 32(40):4814-24. doi:10.1038/onc.2012.494
-
(2012)
Oncogene
, vol.32
, Issue.40
, pp. 4814-4824
-
-
Zhao, J.1
Zhang, J.2
Yu, M.3
Xie, Y.4
Huang, Y.5
Wolff, D.W.6
-
51
-
-
84882668179
-
The role of dynamin-related protein 1 in cancer growth: a promising therapeutic target?
-
doi:10.1517/14728222.2013.823160.
-
Qian W, Wang J, Van Houten B. The role of dynamin-related protein 1 in cancer growth: a promising therapeutic target? Expert Opin Ther Targets (2013) 17:997-1001. doi:10.1517/14728222.2013.823160
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 997-1001
-
-
Qian, W.1
Wang, J.2
Van Houten, B.3
-
52
-
-
84865457924
-
Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-ß-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes
-
30024-34, doi:10.1074/jbc.M112.390682
-
Gawlowski T, Suarez J, Scott B, Torres-Gonzalez M, Wang H, Schwappacher R, et al. Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-ß-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes. J Biol Chem (2012) 287:30024-34. doi:10.1074/jbc.M112.390682
-
(2012)
J Biol Chem
, vol.287
-
-
Gawlowski, T.1
Suarez, J.2
Scott, B.3
Torres-Gonzalez, M.4
Wang, H.5
Schwappacher, R.6
-
53
-
-
84892909254
-
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways
-
doi:10.1172/JCI63146
-
Onodera Y, Nam JM, Bissell MJ. Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways. J Clin Invest (2014) 124(1):367-84. doi:10.1172/JCI63146
-
(2014)
J Clin Invest
, vol.124
, Issue.1
, pp. 367-384
-
-
Onodera, Y.1
Nam, J.M.2
Bissell, M.J.3
-
54
-
-
84880065673
-
O-GlcNAcylation-inducing treatments inhibit estrogen receptor a expression and confer resistance to 4-OH-tamoxifen in human breast cancer-derived MCF-7 cells
-
doi:10.1371/journal.pone.0069150
-
Kanwal S, Fardini Y, Pagesy P, N'tumba-Byn T, Pierre-Eugène C, Masson E, et al. O-GlcNAcylation-inducing treatments inhibit estrogen receptor a expression and confer resistance to 4-OH-tamoxifen in human breast cancer-derived MCF-7 cells. PLoS One (2013) 8(7):e69150. doi:10.1371/journal.pone.0069150
-
(2013)
PLoS One
, vol.8
, Issue.7
-
-
Kanwal, S.1
Fardini, Y.2
Pagesy, P.3
N'tumba-Byn, T.4
Pierre-Eugène, C.5
Masson, E.6
-
55
-
-
33646568511
-
Mechanisms and strategies to overcome multiple drug resistance in cancer
-
doi:10.1016/j.febslet.2006.02.020
-
Ozben T. Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett (2006) 580(12):2903-9. doi:10.1016/j.febslet.2006.02.020
-
(2006)
FEBS Lett
, vol.580
, Issue.12
, pp. 2903-2909
-
-
Ozben, T.1
-
56
-
-
84890934219
-
O-GlcNAcylation of cofilin promotes breast cancer cell invasion
-
36418-25, doi:10.1074/jbc.M113.495713
-
Huang X, Pan Q, Sun D, Chen W, Shen A, Huang M, et al. O-GlcNAcylation of cofilin promotes breast cancer cell invasion. J Biol Chem (2013) 288(51):36418-25. doi:10.1074/jbc.M113.495713
-
(2013)
J Biol Chem
, vol.288
, Issue.51
-
-
Huang, X.1
Pan, Q.2
Sun, D.3
Chen, W.4
Shen, A.5
Huang, M.6
-
57
-
-
84877910937
-
Oncoapoptotic signaling and deregulated target genes in cancers: special reference to oral cancer
-
doi:10.1016/j.bbcan.2013.04.002
-
Khan Z, Bisen PS. Oncoapoptotic signaling and deregulated target genes in cancers: special reference to oral cancer. Biochim Biophys Acta (2013) 1836(1):123-45. doi:10.1016/j.bbcan.2013.04.002
-
(2013)
Biochim Biophys Acta
, vol.1836
, Issue.1
, pp. 123-145
-
-
Khan, Z.1
Bisen, P.S.2
-
58
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
doi:10.1016/j.semcancer.2006.07.015
-
Vita M, Henriksson M. The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol (2006) 16(4):318-30. doi:10.1016/j.semcancer.2006.07.015
-
(2006)
Semin Cancer Biol
, vol.16
, Issue.4
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
59
-
-
0029049198
-
c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas
-
18961-5, doi:10.1074/jbc.270.32.18961
-
Chou TY, Hart GW, Dang CV. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J Biol Chem (1995) 270(32):18961-5. doi:10.1074/jbc.270.32.18961
-
(1995)
J Biol Chem
, vol.270
, Issue.32
-
-
Chou, T.Y.1
Hart, G.W.2
Dang, C.V.3
-
60
-
-
0034306997
-
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
-
doi:10.1101/gad.836800
-
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev (2000) 14:2501-14. doi:10.1101/gad.836800
-
(2000)
Genes Dev
, vol.14
, pp. 2501-2514
-
-
Sears, R.1
Nuckolls, F.2
Haura, E.3
Taya, Y.4
Tamai, K.5
Nevins, J.R.6
-
61
-
-
33749160125
-
Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability
-
Erratum in: Nat Cell Biol (2007) 9(12):1442, doi:10.1038/ncb147
-
Yang WH, Kim JE, Nam HW, Ju JW, Kim HS, Kim YS, et al. Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability. Nat Cell Biol (2006) 8(10):1074-83 Erratum in: Nat Cell Biol (2007) 9(12):1442. doi:10.1038/ncb1470
-
(2006)
Nat Cell Biol
, vol.8
, Issue.10
, pp. 1074-1083
-
-
Yang, W.H.1
Kim, J.E.2
Nam, H.W.3
Ju, J.W.4
Kim, H.S.5
Kim, Y.S.6
-
62
-
-
56049101623
-
Regulation of Akt signaling by O-GlcNAc in euglycemia
-
doi:10.1152/ajpendo.90366.2008
-
Soesanto YA, Luo B, Jones D, Taylor R, Gabrielsen JS, Parker G, et al. Regulation of Akt signaling by O-GlcNAc in euglycemia. Am J Physiol Endocrinol Metab (2008) 295(4):E974-80. doi:10.1152/ajpendo.90366.2008
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, Issue.4
-
-
Soesanto, Y.A.1
Luo, B.2
Jones, D.3
Taylor, R.4
Gabrielsen, J.S.5
Parker, G.6
-
63
-
-
16644403520
-
Prediction of TP53 status for primary cisplatin, fluorouracil, and leucovorin chemotherapy in ethmoid sinus intestinal-type adenocarcinoma
-
doi:10.1200/jco.2004.05.071
-
Licitra L, Suardi S, Bossi P, Locati LD, Mariani L, Quattrone P, et al. Prediction of TP53 status for primary cisplatin, fluorouracil, and leucovorin chemotherapy in ethmoid sinus intestinal-type adenocarcinoma. J Clin Oncol (2004) 22(24):4901-6. doi:10.1200/jco.2004.05.071
-
(2004)
J Clin Oncol
, vol.22
, Issue.24
, pp. 4901-4906
-
-
Licitra, L.1
Suardi, S.2
Bossi, P.3
Locati, L.D.4
Mariani, L.5
Quattrone, P.6
-
64
-
-
0032904567
-
Mutational spectrum of p53 gene in arsenic-related skin cancers from the blackfoot disease endemic area of Taiwan
-
doi:10.1038/sj.bjc.6690467
-
Hsu CH, Yang SA, Wang JY, Yu HS, Lin SR. Mutational spectrum of p53 gene in arsenic-related skin cancers from the blackfoot disease endemic area of Taiwan. Br J Cancer (1999) 80:1080-6. doi:10.1038/sj.bjc.6690467
-
(1999)
Br J Cancer
, vol.80
, pp. 1080-1086
-
-
Hsu, C.H.1
Yang, S.A.2
Wang, J.Y.3
Yu, H.S.4
Lin, S.R.5
-
65
-
-
79960052850
-
Ras in cancer and developmental diseases
-
doi:10.1177/1947601911411084
-
Fernández-Medarde A, Santos E. Ras in cancer and developmental diseases. Genes Cancer (2011) 2(3):344-58. doi:10.1177/1947601911411084
-
(2011)
Genes Cancer
, vol.2
, Issue.3
, pp. 344-358
-
-
Fernández-Medarde, A.1
Santos, E.2
-
66
-
-
33646577163
-
Genetics and biology of pancreatic ductal adenocarcinoma
-
doi:10.1101/gad.1415606
-
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev (2006) 20(10):1218-49. doi:10.1101/gad.1415606
-
(2006)
Genes Dev
, vol.20
, Issue.10
, pp. 1218-1249
-
-
Hezel, A.F.1
Kimmelman, A.C.2
Stanger, B.Z.3
Bardeesy, N.4
Depinho, R.A.5
-
67
-
-
0024376173
-
Ras oncogenes in human cancer: a review
-
Erratum in: Cancer Res (1990) 50(4):1352
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res (1989) 49(17):4682-9 Erratum in: Cancer Res (1990) 50(4):1352.
-
(1989)
Cancer Res
, vol.49
, Issue.17
, pp. 4682-4689
-
-
Bos, J.L.1
-
68
-
-
84860321700
-
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
-
doi:10.1016/j.cell.2012.01.058
-
Ying H, Kimmelman AC, Lyssiotis CA, Chu S, Fletcher-Sananikone E, Locasale JW, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell (2012) 149(3):656-70. doi:10.1016/j.cell.2012.01.058
-
(2012)
Cell
, vol.149
, Issue.3
, pp. 656-670
-
-
Ying, H.1
Kimmelman, A.C.2
Lyssiotis, C.A.3
Chu, S.4
Fletcher-Sananikone, E.5
Locasale, J.W.6
-
69
-
-
84881055345
-
Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response
-
doi:10.1038/cddis.2013.257
-
Palorini R, Cammarata FP, Balestrieri C, Monestiroli A, Vasso M, Gelfi C, et al. Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response. Cell Death Dis (2013) 4:e732. doi:10.1038/cddis.2013.257
-
(2013)
Cell Death Dis
, vol.4
-
-
Palorini, R.1
Cammarata, F.P.2
Balestrieri, C.3
Monestiroli, A.4
Vasso, M.5
Gelfi, C.6
-
70
-
-
84887020540
-
Targeting the AMP-activated protein kinase for cancer prevention and therapy
-
doi:10.3389/fonc.2013.00175
-
Kim I, He YY. Targeting the AMP-activated protein kinase for cancer prevention and therapy. Front Oncol (2013) 3:175. doi:10.3389/fonc.2013.00175
-
(2013)
Front Oncol
, vol.3
, pp. 175
-
-
Kim, I.1
He, Y.Y.2
-
71
-
-
45149095784
-
AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation
-
13009-20, doi:10.1074/jbc.M801222200
-
Cheung WD, Hart GW. AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation. J Biol Chem (2008) 283(19):13009-20. doi:10.1074/jbc.M801222200
-
(2008)
J Biol Chem
, vol.283
, Issue.19
-
-
Cheung, W.D.1
Hart, G.W.2
-
72
-
-
84898613353
-
Crosstalk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK)
-
10592-606, doi:10.1074/jbc.M113.523068
-
Bullen JW, Balsbaugh JL, Chanda D, Shabanowitz J, Hunt DF, Neumann D, et al. Crosstalk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK). J Biol Chem (2014) 289:10592-606. doi:10.1074/jbc.M113.523068
-
(2014)
J Biol Chem
, vol.289
-
-
Bullen, J.W.1
Balsbaugh, J.L.2
Chanda, D.3
Shabanowitz, J.4
Hunt, D.F.5
Neumann, D.6
-
73
-
-
77956396829
-
Oncogenic activation of NF-kappaB
-
a000109, doi:10.1101/cshperspect.a000109
-
Staudt LM. Oncogenic activation of NF-kappaB. Cold Spring Harb Perspect Biol (2010) 2(6):a000109. doi:10.1101/cshperspect.a000109
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.6
-
-
Staudt, L.M.1
-
74
-
-
77953537219
-
Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury
-
doi:10.1016/j.ejphar.2010.04.033.
-
Liu W, Zhang X, Liu P, Shen X, Lan T, Li W, et al. Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury. Eur J Pharmacol (2010) 638(1-3):150-5. doi:10.1016/j.ejphar.2010.04.033
-
(2010)
Eur J Pharmacol
, vol.638
, Issue.1-3
, pp. 150-155
-
-
Liu, W.1
Zhang, X.2
Liu, P.3
Shen, X.4
Lan, T.5
Li, W.6
-
75
-
-
56249095514
-
NFkappaB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions
-
17345-50, doi:10.1073/pnas.0806198105
-
Yang WH, Park SY, Nam HW, Kim Do H, Kang JG, Kang ES, et al. NFkappaB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions. Proc Natl Acad Sci U S A (2008) 105(45):17345-50. doi:10.1073/pnas.0806198105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.45
-
-
Yang, W.H.1
Park, S.Y.2
Nam, H.W.3
Kim Do, H.4
Kang, J.G.5
Kang, E.S.6
-
76
-
-
84867650919
-
Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription
-
16888-93, doi:10.1073/pnas.1208468109
-
Allison DF, Wamsley JJ, Kumar M, Li D, Gray LG, Hart GW, et al. Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription. Proc Natl Acad Sci U S A (2012) 109(42):16888-93. doi:10.1073/pnas.1208468109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.42
-
-
Allison, D.F.1
Wamsley, J.J.2
Kumar, M.3
Li, D.4
Gray, L.G.5
Hart, G.W.6
-
77
-
-
62549161375
-
Loss of p53 enhances catalytic activity of IKKß through O-linked ß-N-acetyl glucosamine modification
-
doi:10.1073/pnas.0813210106
-
Kawauchi K, Araki K, Tobiume K, Tanaka N. Loss of p53 enhances catalytic activity of IKKß through O-linked ß-N-acetyl glucosamine modification. Proc Natl Acad Sci U S A (2009) 106(9):3431-6. doi:10.1073/pnas.0813210106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.9
, pp. 3431-3436
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
|