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Volumn 231, Issue 8, 2016, Pages 1635-1637

SGLT2 Inhibitors: Glucotoxicity and Tumorigenesis Downstream the Renal Proximal Tubule?

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; GLUCOSE; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; SLC5A2 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 84952838207     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25286     Document Type: Article
Times cited : (8)

References (38)
  • 3
    • 35848941694 scopus 로고    scopus 로고
    • Renal carcinogenesis in models of diabetes in rats: Metabolic changes are closely related to neoplastic development
    • Dombrowski F, Klotz L, Bannasch P, Evert M. 2007. Renal carcinogenesis in models of diabetes in rats: Metabolic changes are closely related to neoplastic development. Diabetologia 50:2580-2590.
    • (2007) Diabetologia , vol.50 , pp. 2580-2590
    • Dombrowski, F.1    Klotz, L.2    Bannasch, P.3    Evert, M.4
  • 4
    • 84885600674 scopus 로고    scopus 로고
    • Proteinuria: It is time to look beyond the proximal tubule
    • Erkan E. 2013. Proteinuria: It is time to look beyond the proximal tubule. Am J Physiol Renal Physiol 305:F1107-F1108.
    • (2013) Am J Physiol Renal Physiol , vol.305 , pp. F1107-F1108
    • Erkan, E.1
  • 5
    • 84923527667 scopus 로고    scopus 로고
    • Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences
    • Gallo LA, Wright EM, Vallon V. 2015. Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences. Diab Vasc Dis Res 12:78-89.
    • (2015) Diab Vasc Dis Res , vol.12 , pp. 78-89
    • Gallo, L.A.1    Wright, E.M.2    Vallon, V.3
  • 6
    • 84924263307 scopus 로고    scopus 로고
    • Inhibition of kidney proximal tubular glucose reabsorption does not prevent against diabetic nephropathy in type 1 diabetic eNOS knockout mice
    • Gangadharan Komala M, Gross S, Mudaliar H, Huang C, Pegg K, Mather A, Shen S, Pollock CA, Panchapakesan U. 2014. Inhibition of kidney proximal tubular glucose reabsorption does not prevent against diabetic nephropathy in type 1 diabetic eNOS knockout mice. PLoS ONE 9:e108994.
    • (2014) PLoS ONE , vol.9 , pp. e108994
    • Gangadharan Komala, M.1    Gross, S.2    Mudaliar, H.3    Huang, C.4    Pegg, K.5    Mather, A.6    Shen, S.7    Pollock, C.A.8    Panchapakesan, U.9
  • 9
    • 84899473833 scopus 로고    scopus 로고
    • Diagnosis and treatment of diabetic kidney disease
    • Gosmanov AR, Wall BM, Gosmanova EO. 2014. Diagnosis and treatment of diabetic kidney disease. Am J Med Sci 347:406-413.
    • (2014) Am J Med Sci , vol.347 , pp. 406-413
    • Gosmanov, A.R.1    Wall, B.M.2    Gosmanova, E.O.3
  • 10
    • 84867367085 scopus 로고    scopus 로고
    • Functional expression of TRPV4 channels in human collecting duct cells: Implications for secondary hypertension in diabetic nephropathy
    • Hills CE, Bland R, Squires PE. 2012. Functional expression of TRPV4 channels in human collecting duct cells: Implications for secondary hypertension in diabetic nephropathy. Exp Diabetes Res 2012:936518.
    • (2012) Exp Diabetes Res , vol.2012 , pp. 936518
    • Hills, C.E.1    Bland, R.2    Squires, P.E.3
  • 11
    • 21144439198 scopus 로고    scopus 로고
    • Glycogen accumulation in renal tubules, a key morphological change in the diabetic rat kidney
    • Kang J, Dai XS, Yu TB, Wen B, Yang ZW. 2005. Glycogen accumulation in renal tubules, a key morphological change in the diabetic rat kidney. Acta Diabetol 42:110-116.
    • (2005) Acta Diabetol , vol.42 , pp. 110-116
    • Kang, J.1    Dai, X.S.2    Yu, T.B.3    Wen, B.4    Yang, Z.W.5
  • 12
    • 84926098474 scopus 로고    scopus 로고
    • Clinical implication of SGLT2 inhibitors in type 2 diabetes
    • Kim GW, Chung SH. 2014. Clinical implication of SGLT2 inhibitors in type 2 diabetes. Arch Pharm Res 37:957-966.
    • (2014) Arch Pharm Res , vol.37 , pp. 957-966
    • Kim, G.W.1    Chung, S.H.2
  • 13
    • 84878373118 scopus 로고    scopus 로고
    • Attenuation of Armanni-Ebstein lesions in a rat model of diabetes by a new anti-fibrotic, anti-inflammatory agent, FT011
    • Lau X, Zhang Y, Kelly DJ, Stapleton DI. 2013. Attenuation of Armanni-Ebstein lesions in a rat model of diabetes by a new anti-fibrotic, anti-inflammatory agent, FT011. Diabetologia 56:579-675.
    • (2013) Diabetologia , vol.56 , pp. 579-675
    • Lau, X.1    Zhang, Y.2    Kelly, D.J.3    Stapleton, D.I.4
  • 14
    • 84921480876 scopus 로고    scopus 로고
    • A review on the relationship between SGLT2 inhibitors and cancer
    • Lin HW, Tseng CH. 2014. A review on the relationship between SGLT2 inhibitors and cancer. Int J Endocrinol 2014:719578.
    • (2014) Int J Endocrinol , vol.2014 , pp. 719578
    • Lin, H.W.1    Tseng, C.H.2
  • 15
    • 84964696031 scopus 로고    scopus 로고
    • Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice
    • Lin B, Koibuchi N, Hasegawa Y, Sueta D, Toyama K, Uekawa K, Ma M, Nakagawa T, Kusaka H, Kim-Mitsuyama S. 2014. Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice. Cardiovasc Diabetol 13:148.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 148
    • Lin, B.1    Koibuchi, N.2    Hasegawa, Y.3    Sueta, D.4    Toyama, K.5    Uekawa, K.6    Ma, M.7    Nakagawa, T.8    Kusaka, H.9    Kim-Mitsuyama, S.10
  • 16
    • 32244438686 scopus 로고    scopus 로고
    • Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy
    • Linden KC, DeHaan CL, Zhang Y, Glowacka S, Cox AJ, Kelly DJ, Rogers S. 2006. Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy. Am J Physiol Renal Physiol 290:F205-F213.
    • (2006) Am J Physiol Renal Physiol , vol.290 , pp. F205-F213
    • Linden, K.C.1    DeHaan, C.L.2    Zhang, Y.3    Glowacka, S.4    Cox, A.J.5    Kelly, D.J.6    Rogers, S.7
  • 22
    • 84931083269 scopus 로고    scopus 로고
    • Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods
    • Pujol-Gimenez J, Pérez A, Reyes AM, Loo DD, Lostao MP. 2015b. Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods. Am J Physiol Cell Physiol 308:C1008-C1022.
    • (2015) Am J Physiol Cell Physiol , vol.308 , pp. C1008-C1022
    • Pujol-Gimenez, J.1    Pérez, A.2    Reyes, A.M.3    Loo, D.D.4    Lostao, M.P.5
  • 25
    • 0001359534 scopus 로고
    • The pathology of Armanni-Ebstein diabetic nephropathy
    • Ritchie S, Waugh D. 1957. The pathology of Armanni-Ebstein diabetic nephropathy. Am J Pathol 33:1035-1057.
    • (1957) Am J Pathol , vol.33 , pp. 1035-1057
    • Ritchie, S.1    Waugh, D.2
  • 26
    • 84870519496 scopus 로고    scopus 로고
    • Linking glycogen and senescence in cancer cells
    • Ros S, Schulze A. 2012. Linking glycogen and senescence in cancer cells. Cell Metab 16:687-688.
    • (2012) Cell Metab , vol.16 , pp. 687-688
    • Ros, S.1    Schulze, A.2
  • 27
    • 75749094398 scopus 로고    scopus 로고
    • Familial renal glucosuria and SGL T2: From a mendelian trait to a therapeutic target
    • Santer R, Calado J. 2010. Familial renal glucosuria and SGL T2: From a mendelian trait to a therapeutic target. Clin J Am Soc Nephrol 5:133-141.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 133-141
    • Santer, R.1    Calado, J.2
  • 28
    • 41349110662 scopus 로고    scopus 로고
    • Mechanisms of disease: The hypoxic tubular hypothesis of diabetic nephropathy
    • Singh DK, Winocour P, Farrington K. 2008. Mechanisms of disease: The hypoxic tubular hypothesis of diabetic nephropathy. Nat Clin Pract Nephrol 4:216-226.
    • (2008) Nat Clin Pract Nephrol , vol.4 , pp. 216-226
    • Singh, D.K.1    Winocour, P.2    Farrington, K.3
  • 29
    • 69949101547 scopus 로고    scopus 로고
    • Insulin-stimulated translocation of glucose transporter (GLUT) 12 parallels that of GLUT4 in normal muscle
    • Stuart CA, Howell ME, Zhang Y, Yin D. 2009. Insulin-stimulated translocation of glucose transporter (GLUT) 12 parallels that of GLUT4 in normal muscle. J Clin Endocrinol Metab 94:3535-3542.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3535-3542
    • Stuart, C.A.1    Howell, M.E.2    Zhang, Y.3    Yin, D.4
  • 32
    • 84892588641 scopus 로고    scopus 로고
    • SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice
    • Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. 2014. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol 306:F194-F204.
    • (2014) Am J Physiol Renal Physiol , vol.306 , pp. F194-F204
    • Vallon, V.1    Gerasimova, M.2    Rose, M.A.3    Masuda, T.4    Satriano, J.5    Mayoux, E.6    Koepsell, H.7    Thomson, S.C.8    Rieg, T.9
  • 33
    • 79955771730 scopus 로고    scopus 로고
    • The proximal tubule in the pathophysiology of the diabetic kidney
    • Vallon V. 2011. The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol 300:R1009-R1022.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300 , pp. R1009-R1022
    • Vallon, V.1
  • 34
    • 38349086642 scopus 로고    scopus 로고
    • Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells
    • Vogetseder A, Picard N, Gaspert A, Walch M, Kaissling B, Le Hir M. 2008. Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells. Am J Physiol Cell Physiol 294:C22-C28.
    • (2008) Am J Physiol Cell Physiol , vol.294 , pp. C22-C28
    • Vogetseder, A.1    Picard, N.2    Gaspert, A.3    Walch, M.4    Kaissling, B.5    Le Hir, M.6
  • 36
    • 40849098654 scopus 로고    scopus 로고
    • Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells
    • Wilson-O'Brien AL, Dehaan CL, Rogers S. 2008. Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells. Endocrinology 149:917-924.
    • (2008) Endocrinology , vol.149 , pp. 917-924
    • Wilson-O'Brien, A.L.1    Dehaan, C.L.2    Rogers, S.3
  • 37
    • 19944433001 scopus 로고    scopus 로고
    • Different involvement for aldolase isoenzymes in kidney glucose metabolism: Aldolase B but not aldolase A colocalizes and forms a complex with FBPase
    • Yanez AJ, Ludwig HC, Bertinat R, Spichiger C, Gatica R, Berlien G, Leon O, Brito M, Concha II, Slebe JC. 2005. Different involvement for aldolase isoenzymes in kidney glucose metabolism: Aldolase B but not aldolase A colocalizes and forms a complex with FBPase. J Cell Physiol 202:743-753.
    • (2005) J Cell Physiol , vol.202 , pp. 743-753
    • Yanez, A.J.1    Ludwig, H.C.2    Bertinat, R.3    Spichiger, C.4    Gatica, R.5    Berlien, G.6    Leon, O.7    Brito, M.8    Concha, I.I.9    Slebe, J.C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.