The protective effect of shikonin on renal tubular epithelial cell injury induced by high glucose

Biomedicine and Pharmacotherapy

Volumn 98, Issue , 2018, Pages 701-708

  Tong, Yuna ^a   Chuan, Junlan ^b   Bai, Lan ^b   Shi, Jianyou ^b   Zhong, Lei ^b   Duan, Xingmei ^b   Zhu, Yuxuan ^b  

^a Third Hospital of Chengdu   (China)

^b UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Diabetic nephropathy; Hyperglycemia; NRK 52E cell; Oxidative stress; Shikonin

Indexed keywords

CASPASE 3; CELL NUCLEUS DNA; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; LACTATE DEHYDROGENASE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; SHIKONIN; ANTIOXIDANT; NAPHTHOQUINONE; PROTECTIVE AGENT;

AKT SIGNALING; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DIABETIC NEPHROPATHY; HYPERGLYCEMIA; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; LIPID PEROXIDATION; LITHOSPERMUM; MITOCHONDRIAL MEMBRANE POTENTIAL; NRK-52E CELL LINE; OXIDATIVE STRESS; PRIORITY JOURNAL; RENAL PROTECTION; ANIMAL; CELL LINE; CELL SURVIVAL; DRUG EFFECT; EPITHELIUM CELL; KIDNEY PROXIMAL TUBULE; METABOLISM; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; DIABETIC NEPHROPATHIES; EPITHELIAL CELLS; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3 BETA; KIDNEY TUBULES, PROXIMAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; NAPHTHOQUINONES; OXIDATIVE STRESS; PROTECTIVE AGENTS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85039857072     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.12.112     Document Type: Article

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