Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance

Aging Cell

Volumn 17, Issue 4, 2018, Pages

  Gulshan, Maryam ^a,b   Yaku, Keisuke ^a,b   Okabe, Keisuke ^a,b   Mahmood, Arshad ^a,b   Sasaki, Tsutomu ^c   Yamamoto, Masashi ^a,b,d   Hikosaka, Keisuke ^a   Usui, Isao ^b   Kitamura, Tadahiro ^c   Tobe, Kazuyuki ^b   Nakagawa, Takashi ^a,b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

aging; insulin resistance; NGD; nicotinamide adenine dinucleotide; Nmnat3; reactive oxygen species

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE GUANINE DINUCLEOTIDE; NMNAT3 PROTEIN; NUCLEOTIDE DERIVATIVE; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 3, MOUSE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE;

AGE; AGE ASSOCIATED INSULIN RESISTANCE; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENERGY RESOURCE; FATTY ACID OXIDATION; INSULIN RESISTANCE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; SYNTHESIS; ANIMAL; BIOSYNTHESIS; CALORIMETRY; CELL AGING; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; CALORIMETRY; CELLULAR SENESCENCE; GUANINE NUCLEOTIDES; INSULIN RESISTANCE; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; NAD; NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE; REACTIVE OXYGEN SPECIES;

EID: 85050311934     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12798     Document Type: Article

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