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Volumn 11, Issue 1, 2016, Pages

Nmnat3 is dispensable in mitochondrial NAD level maintenance in vivo

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 1; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 2; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 3; TRANSFERASE; UNCLASSIFIED DRUG; NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 3, MOUSE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE;

EID: 84954536421     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147037     Document Type: Article
Times cited : (58)

References (40)
  • 2
    • 40849119972 scopus 로고    scopus 로고
    • NAD+ and vitamin B3: From metabolism to therapies
    • 18165311
    • Sauve AA (2008) NAD+ and vitamin B3: from metabolism to therapies. J Pharmacol Exp Ther 324: 883-893. doi: 10.1124/jpet.107.120758 PMID: 18165311
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 883-893
    • Sauve, A.A.1
  • 3
    • 84865411082 scopus 로고    scopus 로고
    • The dynamic regulation of NAD metabolism in mitochondria
    • 22819213
    • Stein LR, Imai S (2012) The dynamic regulation of NAD metabolism in mitochondria. Trends Endocrinol Metab 23: 420-428. doi: 10.1016/j.tem.2012.06.005 PMID: 22819213
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 420-428
    • Stein, L.R.1    Imai, S.2
  • 4
    • 0017747012 scopus 로고
    • Pyridine nucleotide distributions and enzyme mass action ratios in hepatocytes from fed and starved rats
    • 21628
    • Tischler ME, Friedrichs D, Coll K, Williamson JR (1977) Pyridine nucleotide distributions and enzyme mass action ratios in hepatocytes from fed and starved rats. Arch Biochem Biophys 184: 222-236. PMID: 21628
    • (1977) Arch Biochem Biophys , vol.184 , pp. 222-236
    • Tischler, M.E.1    Friedrichs, D.2    Coll, K.3    Williamson, J.R.4
  • 5
    • 0035831080 scopus 로고    scopus 로고
    • Pathophysiological relevance of mitochondria in NAD(+) metabolism
    • 11248227
    • Di Lisa F, Ziegler M (2001) Pathophysiological relevance of mitochondria in NAD(+) metabolism. FEBS Lett 492: 4-8. PMID: 11248227
    • (2001) FEBS Lett , vol.492 , pp. 4-8
    • Di Lisa, F.1    Ziegler, M.2
  • 6
    • 79957549799 scopus 로고    scopus 로고
    • Pathways and subcellular compartmentation of NAD biosynthesis in human cells: From entry of extracellular precursors to mitochondrial NAD generation
    • 21504897
    • Nikiforov A, Dolle C, Niere M, Ziegler M (2011) Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation. J Biol Chem 286: 21767-21778. doi: 10.1074/jbc.M110.213298 PMID: 21504897
    • (2011) J Biol Chem , vol.286 , pp. 21767-21778
    • Nikiforov, A.1    Dolle, C.2    Niere, M.3    Ziegler, M.4
  • 7
    • 0000535911 scopus 로고
    • Localization and kinetics of reduced pyridine nucleotide in living cells by microfluorometry
    • 13809109
    • Chance B, Thorell B (1959) Localization and kinetics of reduced pyridine nucleotide in living cells by microfluorometry. J Biol Chem 234: 3044-3050. PMID: 13809109
    • (1959) J Biol Chem , vol.234 , pp. 3044-3050
    • Chance, B.1    Thorell, B.2
  • 8
    • 17544384058 scopus 로고    scopus 로고
    • Fluxes of nicotinamide adenine dinucleotides through mitochondrial membranes in human cultured cells
    • 8663005
    • Rustin P, Parfait B, Chretien D, Bourgeron T, Djouadi F, Bastin J, et al. (1996) Fluxes of nicotinamide adenine dinucleotides through mitochondrial membranes in human cultured cells. J Biol Chem 271: 14785-14790. PMID: 8663005
    • (1996) J Biol Chem , vol.271 , pp. 14785-14790
    • Rustin, P.1    Parfait, B.2    Chretien, D.3    Bourgeron, T.4    Djouadi, F.5    Bastin, J.6
  • 9
    • 0029737904 scopus 로고    scopus 로고
    • Rat liver mitochondria can synthesize nicotinamide adenine dinucleotide from nicotinamide mononucleotide and ATP via a putative matrix nicotinamide mononucleotide adenylyltransferase
    • 8850525
    • Barile M, Passarella S, Danese G, Quagliariello E (1996) Rat liver mitochondria can synthesize nicotinamide adenine dinucleotide from nicotinamide mononucleotide and ATP via a putative matrix nicotinamide mononucleotide adenylyltransferase. Biochem Mol Biol Int 38: 297-306. PMID: 8850525
    • (1996) Biochem Mol Biol Int , vol.38 , pp. 297-306
    • Barile, M.1    Passarella, S.2    Danese, G.3    Quagliariello, E.4
  • 11
    • 0000548121 scopus 로고
    • Cytochemical studies. VI. The synthesis of diphosphopyridine nucleotide by liver cell nuclei
    • 12981091
    • Hogeboom GH, Schneider WC (1952) Cytochemical studies. VI. The synthesis of diphosphopyridine nucleotide by liver cell nuclei. J Biol Chem 197: 611-620. PMID: 12981091
    • (1952) J Biol Chem , vol.197 , pp. 611-620
    • Hogeboom, G.H.1    Schneider, W.C.2
  • 12
    • 0017389301 scopus 로고
    • Synthesis of pyridine nucleotides by mitochondrial fractions of yeast
    • 194601
    • Lange RA, Jacobson MK (1976) Synthesis of pyridine nucleotides by mitochondrial fractions of yeast. Biochem Biophys Res Commun 76: 424-428. PMID: 194601
    • (1976) Biochem Biophys Res Commun , vol.76 , pp. 424-428
    • Lange, R.A.1    Jacobson, M.K.2
  • 13
    • 0019879843 scopus 로고
    • Apparent pyridine nucleotide synthesis in mitochondria: An artifact of NMN and NAD glycohydrolase activity?
    • 6272769
    • Behr A, Taguchi H, Gholson RK (1981) Apparent pyridine nucleotide synthesis in mitochondria: an artifact of NMN and NAD glycohydrolase activity? Biochem Biophys Res Commun 101: 767-774. PMID: 6272769
    • (1981) Biochem Biophys Res Commun , vol.101 , pp. 767-774
    • Behr, A.1    Taguchi, H.2    Gholson, R.K.3
  • 14
    • 84884596730 scopus 로고    scopus 로고
    • Diversification of NAD biological role: The importance of location
    • 23848828
    • Di Stefano M, Conforti L (2013) Diversification of NAD biological role: the importance of location. FEBS J 280: 4711-4728. doi: 10.1111/febs.12433 PMID: 23848828
    • (2013) FEBS J , vol.280 , pp. 4711-4728
    • Di Stefano, M.1    Conforti, L.2
  • 15
    • 84880328473 scopus 로고    scopus 로고
    • NAD and ADP-ribose metabolism in mitochondria
    • 23617329
    • Dolle C, Rack JG, Ziegler M (2013) NAD and ADP-ribose metabolism in mitochondria. FEBS J 280: 3530-3541. doi: 10.1111/febs.12304 PMID: 23617329
    • (2013) FEBS J , vol.280 , pp. 3530-3541
    • Dolle, C.1    Rack, J.G.2    Ziegler, M.3
  • 16
    • 84937522438 scopus 로고    scopus 로고
    • NAD(+) metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus
    • 26118927
    • Canto C, Menzies KJ, Auwerx J (2015) NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metab 22: 31-53. doi: 10.1016/j.cmet. 2015.05.023 PMID: 26118927
    • (2015) Cell Metab , vol.22 , pp. 31-53
    • Canto, C.1    Menzies, K.J.2    Auwerx, J.3
  • 17
    • 0035831109 scopus 로고    scopus 로고
    • Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis
    • 11248244
    • Schweiger M, Hennig K, Lerner F, Niere M, Hirsch-Kauffmann M, Specht T, et al. (2001) Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis. FEBS Lett 492: 95-100. PMID: 11248244
    • (2001) FEBS Lett , vol.492 , pp. 95-100
    • Schweiger, M.1    Hennig, K.2    Lerner, F.3    Niere, M.4    Hirsch-Kauffmann, M.5    Specht, T.6
  • 19
    • 0942279500 scopus 로고    scopus 로고
    • Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas
    • 14516279
    • Yalowitz JA, Xiao S, Biju MP, Antony AC, Cummings OW, Deeg MA, et al. (2004) Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas. Biochem J 377: 317-326. PMID: 14516279
    • (2004) Biochem J , vol.377 , pp. 317-326
    • Yalowitz, J.A.1    Xiao, S.2    Biju, M.P.3    Antony, A.C.4    Cummings, O.W.5    Deeg, M.A.6
  • 20
    • 0038644836 scopus 로고    scopus 로고
    • Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis
    • 12574164
    • Zhang X, Kurnasov OV, Karthikeyan S, Grishin NV, Osterman AL, Zhang H (2003) Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis. J Biol Chem 278: 13503-13511. PMID: 12574164
    • (2003) J Biol Chem , vol.278 , pp. 13503-13511
    • Zhang, X.1    Kurnasov, O.V.2    Karthikeyan, S.3    Grishin, N.V.4    Osterman, A.L.5    Zhang, H.6
  • 21
    • 27744501798 scopus 로고    scopus 로고
    • Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
    • 16118205
    • Berger F, Lau C, Dahlmann M, Ziegler M (2005) Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J Biol Chem 280: 36334-36341. PMID: 16118205
    • (2005) J Biol Chem , vol.280 , pp. 36334-36341
    • Berger, F.1    Lau, C.2    Dahlmann, M.3    Ziegler, M.4
  • 22
    • 84901446681 scopus 로고    scopus 로고
    • Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes
    • 24739386
    • Hikosaka K, Ikutani M, Shito M, Kazuma K, Gulshan M, Nagai Y, et al. (2014) Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes. J Biol Chem 289: 14796-14811. doi: 10.1074/jbc.M114.554378 PMID: 24739386
    • (2014) J Biol Chem , vol.289 , pp. 14796-14811
    • Hikosaka, K.1    Ikutani, M.2    Shito, M.3    Kazuma, K.4    Gulshan, M.5    Nagai, Y.6
  • 23
    • 15844407874 scopus 로고    scopus 로고
    • Cyclophilin ddependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
    • 15800626
    • Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, et al. (2005) Cyclophilin Ddependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434: 652-658. PMID: 15800626
    • (2005) Nature , vol.434 , pp. 652-658
    • Nakagawa, T.1    Shimizu, S.2    Watanabe, T.3    Yamaguchi, O.4    Otsu, K.5    Yamagata, H.6
  • 24
    • 34347236921 scopus 로고    scopus 로고
    • Organelle isolation: Functional mitochondria from mouse liver, muscle and cultured fibroblasts
    • 17406588
    • Frezza C, Cipolat S, Scorrano L (2007) Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts. Nat Protoc 2: 287-295. PMID: 17406588
    • (2007) Nat Protoc , vol.2 , pp. 287-295
    • Frezza, C.1    Cipolat, S.2    Scorrano, L.3
  • 25
    • 84871751837 scopus 로고    scopus 로고
    • Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues
    • 23300904
    • Orsomando G, Cialabrini L, Amici A, Mazzola F, Ruggieri S, Conforti L, et al. (2012) Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues. PLoS One 7: e53271. doi: 10.1371/journal.pone.0053271 PMID: 23300904
    • (2012) PLoS One , vol.7 , pp. e53271
    • Orsomando, G.1    Cialabrini, L.2    Amici, A.3    Mazzola, F.4    Ruggieri, S.5    Conforti, L.6
  • 26
    • 77953631698 scopus 로고    scopus 로고
    • The secret life of NAD+: An old metabolite controlling new metabolic signaling pathways
    • 20007326
    • Houtkooper RH, Canto C, Wanders RJ, Auwerx J (2010) The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Endocr Rev 31: 194-223. doi: 10.1210/er.2009-0026 PMID: 20007326
    • (2010) Endocr Rev , vol.31 , pp. 194-223
    • Houtkooper, R.H.1    Canto, C.2    Wanders, R.J.3    Auwerx, J.4
  • 27
    • 84873291018 scopus 로고    scopus 로고
    • Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: Metabolic basis and potential clinical implications
    • 23239881
    • Tan B, Young DA, Lu ZH, Wang T, Meier TI, Shepard RL, et al. (2013) Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. J Biol Chem 288: 3500-3511. doi: 10.1074/jbc.M112.394510 PMID: 23239881
    • (2013) J Biol Chem , vol.288 , pp. 3500-3511
    • Tan, B.1    Young, D.A.2    Lu, Z.H.3    Wang, T.4    Meier, T.I.5    Shepard, R.L.6
  • 28
    • 79957944139 scopus 로고    scopus 로고
    • NMN/NaMN adenylyltransferase (NMNAT) and NAD kinase (NADK) inhibitors: Chemistry and potential therapeutic applications
    • 21517775
    • Petrelli R, Felczak K, Cappellacci L (2011) NMN/NaMN adenylyltransferase (NMNAT) and NAD kinase (NADK) inhibitors: chemistry and potential therapeutic applications. Curr Med Chem 18: 1973-1992. PMID: 21517775
    • (2011) Curr Med Chem , vol.18 , pp. 1973-1992
    • Petrelli, R.1    Felczak, K.2    Cappellacci, L.3
  • 29
    • 84885396877 scopus 로고    scopus 로고
    • Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria
    • 24155910
    • Felici R, Lapucci A, Ramazzotti M, Chiarugi A (2013) Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria. PLoS One 8: e76938. doi: 10.1371/journal.pone.0076938 PMID: 24155910
    • (2013) PLoS One , vol.8 , pp. e76938
    • Felici, R.1    Lapucci, A.2    Ramazzotti, M.3    Chiarugi, A.4
  • 30
    • 77953139085 scopus 로고    scopus 로고
    • Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells
    • 20457531
    • Di Stefano M, Galassi L, Magni G (2010) Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells. Blood Cells Mol Dis 45: 33-39. doi: 10.1016/j. bcmd.2010.04.003 PMID: 20457531
    • (2010) Blood Cells Mol Dis , vol.45 , pp. 33-39
    • Di Stefano, M.1    Galassi, L.2    Magni, G.3
  • 31
    • 0031799733 scopus 로고    scopus 로고
    • Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondria
    • 9603986
    • Omura T (1998) Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondria. J Biochem 123: 1010-1016. PMID: 9603986
    • (1998) J Biochem , vol.123 , pp. 1010-1016
    • Omura, T.1
  • 32
    • 0029915525 scopus 로고    scopus 로고
    • Computational method to predict mitochondrially imported proteins and their targeting sequences
    • 8944766
    • Claros MG, Vincens P (1996) Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur J Biochem 241: 779-786. PMID: 8944766
    • (1996) Eur J Biochem , vol.241 , pp. 779-786
    • Claros, M.G.1    Vincens, P.2
  • 33
    • 84901720737 scopus 로고    scopus 로고
    • YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in saccharomyces cerevisiae
    • 24759102
    • Kato M, Lin SJ (2014) YCL047C/POF1 is a novel nicotinamide mononucleotide adenylyltransferase (NMNAT) in Saccharomyces cerevisiae. J Biol Chem 289: 15577-15587. doi: 10.1074/jbc.M114. 558643 PMID: 24759102
    • (2014) J Biol Chem , vol.289 , pp. 15577-15587
    • Kato, M.1    Lin, S.J.2
  • 34
    • 0001434694 scopus 로고
    • The relation between intra- and extramitochondrial pyridine nucleotides
    • 14489268
    • Purvis JL, Lowenstein JM (1961) The relation between intra- and extramitochondrial pyridine nucleotides. J Biol Chem 236: 2794-2803. PMID: 14489268
    • (1961) J Biol Chem , vol.236 , pp. 2794-2803
    • Purvis, J.L.1    Lowenstein, J.M.2
  • 35
    • 78651196017 scopus 로고
    • The effect of Ca2+ on dpn and tpn incorporation into rat-liver mitochondria
    • 14325940
    • Greenspan MD, Purvis JL (1965) The Effect of Ca2+ on Dpn and Tpn Incorporation into Rat-Liver Mitochondria. Biochim Biophys Acta 99: 167-170. PMID: 14325940
    • (1965) Biochim Biophys Acta , vol.99 , pp. 167-170
    • Greenspan, M.D.1    Purvis, J.L.2
  • 36
    • 0014409242 scopus 로고
    • The energy-linked incorporation of diphosphopyridine nucleotide into rat liver mitochondria. Requirements for incorporation
    • 4297465
    • Greenspan MD, Purvis JL (1968) The energy-linked incorporation of diphosphopyridine nucleotide into rat liver mitochondria. Requirements for incorporation. J Biol Chem 243: 2921-2927. PMID: 4297465
    • (1968) J Biol Chem , vol.243 , pp. 2921-2927
    • Greenspan, M.D.1    Purvis, J.L.2
  • 37
    • 0035951823 scopus 로고    scopus 로고
    • Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart
    • 11073947
    • Di Lisa F, Menabo R, Canton M, Barile M, Bernardi P (2001) Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart. J Biol Chem 276: 2571-2575. PMID: 11073947
    • (2001) J Biol Chem , vol.276 , pp. 2571-2575
    • Di Lisa, F.1    Menabo, R.2    Canton, M.3    Barile, M.4    Bernardi, P.5
  • 38
    • 33748961353 scopus 로고    scopus 로고
    • Mitochondrial membrane permeability transition and cell death
    • 16716247
    • Tsujimoto Y, Nakagawa T, Shimizu S (2006) Mitochondrial membrane permeability transition and cell death. Biochim Biophys Acta 1757: 1297-1300. PMID: 16716247
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 1297-1300
    • Tsujimoto, Y.1    Nakagawa, T.2    Shimizu, S.3
  • 39
    • 33644513561 scopus 로고    scopus 로고
    • Identification of the mitochondrial NAD+ transporter in saccharomyces cerevisiae
    • 16291748
    • Todisco S, Agrimi G, Castegna A, Palmieri F (2006) Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae. J Biol Chem 281: 1524-1531. PMID: 16291748
    • (2006) J Biol Chem , vol.281 , pp. 1524-1531
    • Todisco, S.1    Agrimi, G.2    Castegna, A.3    Palmieri, F.4
  • 40
    • 71449120312 scopus 로고    scopus 로고
    • Molecular identification and functional characterization of arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins
    • 19745225
    • Palmieri F, Rieder B, Ventrella A, Blanco E, Do PT, Nunes-Nesi A, et al. (2009) Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. J Biol Chem 284: 31249-31259. doi: 10.1074/jbc.M109.041830 PMID: 19745225
    • (2009) J Biol Chem , vol.284 , pp. 31249-31259
    • Palmieri, F.1    Rieder, B.2    Ventrella, A.3    Blanco, E.4    Do, P.T.5    Nunes-Nesi, A.6


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