NAMPT-Mediated NAD+ Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice

Cell Reports

Volumn 16, Issue 7, 2016, Pages 1851-1860

  Stromsdorfer, Kelly L ^a   Yamaguchi, Shintaro ^a   Yoon, Myeong Jin ^a   Moseley, Anna C ^a   Franczyk, Michael P ^a   Kelly, Shannon C ^a   Qi, Nathan ^b   Imai, Shin ichiro ^a   Yoshino, Jun ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

adipocyte; insulin resistance; NAD+; NAMPT; obesity; PPAR

Indexed keywords

ADIPONECTIN; COMPLEMENT FACTOR D; CYCLIN DEPENDENT KINASE 5; FATTY ACID; INSULIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NICOTINIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; SERINE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPOQ PROTEIN, MOUSE; ANTIDIABETIC AGENT; CYTOKINE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, MOUSE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID BLOOD LEVEL; FEMALE; GENE DELETION; GENE EXPRESSION; GENE LOSS; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER; MALE; MOUSE; NAMPT GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE; ANIMAL; BLOOD; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; OBESITY; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; CYCLIN-DEPENDENT KINASE 5; CYTOKINES; FATTY ACIDS, NONESTERIFIED; FEMALE; GENE EXPRESSION REGULATION; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; NICOTINAMIDE MONONUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; OBESITY; PHOSPHORYLATION; PPAR GAMMA; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES;

EID: 84997606246     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.07.027     Document Type: Article

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