Molecular mechanism and inhibitory targets of dioscin in HepG2 cells

Food and Chemical Toxicology

Volumn 120, Issue , 2018, Pages 143-154

  Zhang, Ying Shuo ^a   Ma, Yi Long ^a   Thakur, Kiran ^a   Hussain, Sayed Sajid ^a   Wang, Jun ^a   Zhang, Qi ^a   Zhang, Jian Guo ^a   Wei, Zhao Jun ^a  

^a HEFEI UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Apoptosis; Cell cycle; Dioscin; Molecular mechanism; Polygonatum sibiricum

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 8; CASPASE 9; DIOSCIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SAPONIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DEATH RECEPTOR; DIOSGENIN;

AKT SIGNALING; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; G2 PHASE CELL CYCLE CHECKPOINT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC50; MASS SPECTROMETRY; MITOCHONDRION; MTT ASSAY; PROTEIN EXPRESSION; PROTEIN RNA BINDING; PROTON NUCLEAR MAGNETIC RESONANCE; ANALOGS AND DERIVATIVES; CELL CYCLE G2 PHASE; CELL DIVISION; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; GENE; HEP-G2 CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; POLYGONATUM;

ANTICARCINOGENIC AGENTS; APOPTOSIS; CELL CYCLE PROTEINS; CELL DIVISION; CELL PROLIFERATION; DIOSGENIN; G2 PHASE; GENES, CDC; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MITOCHONDRIA; POLYGONATUM; REACTIVE OXYGEN SPECIES; RECEPTORS, DEATH DOMAIN;

EID: 85049881066     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2018.07.016     Document Type: Article

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