메뉴 건너뛰기




Volumn 20, Issue 7, 2018, Pages 836-846

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CRISPR ASSOCIATED PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; SMALL CYTOPLASMIC RNA; TRANSCRIPTION FACTOR PU 1; ANTIANEMIC AGENT; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; ERYTHROPOIETIN; FILGRASTIM; INTERFERON REGULATORY FACTOR; ONCOPROTEIN; PROTO-ONCOGENE PROTEIN SPI-1; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTOME;

EID: 85048653351     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/s41556-018-0121-4     Document Type: Article
Times cited : (250)

References (70)
  • 1
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: An evolving paradigm for stem cell biology
    • Orkin, S. H. & Zon, L. I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132, 631-644 (2008).
    • (2008) Cell , vol.132 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 2
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • Till, J. E. & Mc, C. E. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat. Res. 14, 213-222 (1961).
    • (1961) Radiat. Res. , vol.14 , pp. 213-222
    • Till, J.E.1    Mc, C.E.2
  • 3
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude, G. J., Heimfeld, S. & Weissman, I. L. Purification and characterization of mouse hematopoietic stem cells. Science 241, 58-62 (1988).
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 4
    • 0014690972 scopus 로고
    • Treatment of lymphopenic hypogammaglobulinemia and bone-marrow aplasia by transplantation of allogeneic marrow. Crucial role of histocompatibility matching
    • Meuwissen, H. J., Gatti, R. A., Terasaki, P. I., Hong, R. & Good, R. A. Treatment of lymphopenic hypogammaglobulinemia and bone-marrow aplasia by transplantation of allogeneic marrow. Crucial role of histocompatibility matching. N. Engl. J. Med. 281, 691-697 (1969).
    • (1969) N. Engl. J. Med. , vol.281 , pp. 691-697
    • Meuwissen, H.J.1    Gatti, R.A.2    Terasaki, P.I.3    Hong, R.4    Good, R.A.5
  • 5
    • 0000970496 scopus 로고
    • Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy
    • Tho, E. D., Lochte, H. L., W, C. L. U. & Ferrebee, J. W. Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N. Engl. J. Med. 257, 491-496 (1957).
    • (1957) N. Engl. J. Med. , vol.257 , pp. 491-496
    • Tho, E.D.1    Lochte, H.L.2    Ferrebee, J.W.3
  • 6
    • 34848883146 scopus 로고    scopus 로고
    • Reciprocal activation of GATA-1 and PU. 1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages
    • Arinobu, Y. et al. Reciprocal activation of GATA-1 and PU. 1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell 1, 416-427 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 416-427
    • Arinobu, Y.1
  • 7
    • 34848896359 scopus 로고    scopus 로고
    • Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
    • Pronk, C. J. et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 1, 428-442 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 428-442
    • Pronk, C.J.1
  • 8
    • 77449093887 scopus 로고    scopus 로고
    • Hematopoietic stem cell heterogeneity: Subtypes, not unpredictable behavior
    • Schroeder, T. Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell Stem Cell 6, 203-207 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 203-207
    • Schroeder, T.1
  • 9
    • 84883428326 scopus 로고    scopus 로고
    • Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
    • Yamamoto, R. et al. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell 154, 1112-1126 (2013).
    • (2013) Cell , vol.154 , pp. 1112-1126
    • Yamamoto, R.1
  • 10
    • 84907419194 scopus 로고    scopus 로고
    • Immunogenetics. Chromatin state dynamics during blood formation
    • Lara-Astiaso, D. et al. Immunogenetics. Chromatin state dynamics during blood formation. Science 345, 943-949 (2014).
    • (2014) Science , vol.345 , pp. 943-949
    • Lara-Astiaso, D.1
  • 11
    • 84922541996 scopus 로고    scopus 로고
    • Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
    • Cabezas-Wallscheid, N. et al. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell 15, 507-522 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 507-522
    • Cabezas-Wallscheid, N.1
  • 12
    • 0026017392 scopus 로고
    • Leukemia and the disruption of normal hematopoiesis
    • Sawyers, C. L., Denny, C. T. & Witte, O. N. Leukemia and the disruption of normal hematopoiesis. Cell 64, 337-350 (1991).
    • (1991) Cell , vol.64 , pp. 337-350
    • Sawyers, C.L.1    Denny, C.T.2    Witte, O.N.3
  • 13
    • 20444456279 scopus 로고    scopus 로고
    • Treatment of severe autoimmune disease by stem-cell transplantation
    • Sykes, M. & Nikolic, B. Treatment of severe autoimmune disease by stem-cell transplantation. Nature 435, 620-627 (2005).
    • (2005) Nature , vol.435 , pp. 620-627
    • Sykes, M.1    Nikolic, B.2
  • 14
    • 84937604921 scopus 로고    scopus 로고
    • An interactive reference framework for modeling a dynamic immune system
    • Spitzer, M. H. et al. An interactive reference framework for modeling a dynamic immune system. Science 349, 1259425 (2015).
    • (2015) Science , vol.349 , pp. 1259425
    • Spitzer, M.H.1
  • 15
    • 84885172419 scopus 로고    scopus 로고
    • Mapping cellular hierarchy byÿsingle-cellÿanalysis of the cell surface repertoire
    • Guo, G. et al. Mapping cellular hierarchy byÿsingle-cellÿanalysis of the cell surface repertoire. Cell Stem Cell 13, 492-505 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 492-505
    • Guo, G.1
  • 16
    • 84950283224 scopus 로고    scopus 로고
    • The branching point in erythro-myeloid differentiation
    • Perie, L., Duffy, K. R., Kok, L., de Boer, R. J. & Schumacher, T. N. The branching point in erythro-myeloid differentiation. Cell 163, 1655-1662 (2015).
    • (2015) Cell , vol.163 , pp. 1655-1662
    • Perie, L.1    Duffy, K.R.2    Kok, L.3    De Boer, R.J.4    Schumacher, T.N.5
  • 17
    • 20244387299 scopus 로고    scopus 로고
    • Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson, J. et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121, 295-306 (2005).
    • (2005) Cell , vol.121 , pp. 295-306
    • Adolfsson, J.1
  • 18
    • 77958522656 scopus 로고    scopus 로고
    • Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
    • Kondo, M. Lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. Immunol. Rev. 238, 37-46 (2010).
    • (2010) Immunol. Rev. , vol.238 , pp. 37-46
    • Kondo, M.1
  • 19
    • 84878532331 scopus 로고    scopus 로고
    • Revision of the human hematopoietic tree: Granulocyte subtypes derive from distinct hematopoietic lineages
    • Gorgens, A. et al. Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages. Cell Rep. 3, 1539-1552 (2013).
    • (2013) Cell Rep. , vol.3 , pp. 1539-1552
    • Gorgens, A.1
  • 20
    • 84950290139 scopus 로고    scopus 로고
    • Transcriptional heterogeneity and lineage commitment in myeloid progenitors
    • Paul, F. et al. Transcriptional heterogeneity and lineage commitment in myeloid progenitors. Cell 163, 1663-1677 (2015).
    • (2015) Cell , vol.163 , pp. 1663-1677
    • Paul, F.1
  • 21
    • 84876297531 scopus 로고    scopus 로고
    • Diverse and heritable lineage imprinting of early haematopoietic progenitors
    • Naik, S. H. et al. Diverse and heritable lineage imprinting of early haematopoietic progenitors. Nature 496, 229-232 (2013).
    • (2013) Nature , vol.496 , pp. 229-232
    • Naik, S.H.1
  • 22
    • 84955164174 scopus 로고    scopus 로고
    • Distinct routes of lineage development reshape the human blood hierarchy across ontogeny
    • Notta, F. et al. Distinct routes of lineage development reshape the human blood hierarchy across ontogeny. Science 351, aab2116 (2016).
    • (2016) Science , vol.351 , pp. aab2116
    • Notta, F.1
  • 23
    • 84885634008 scopus 로고    scopus 로고
    • Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
    • Sanjuan-Pla, A. et al. Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy. Nature 502, 232-236 (2013).
    • (2013) Nature , vol.502 , pp. 232-236
    • Sanjuan-Pla, A.1
  • 24
    • 84893905629 scopus 로고    scopus 로고
    • Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types
    • Jaitin, D. A. et al. Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776-779 (2014).
    • (2014) Science , vol.343 , pp. 776-779
    • Jaitin, D.A.1
  • 25
    • 84941201582 scopus 로고    scopus 로고
    • Single-cell messenger RNA sequencing reveals rare intestinal cell types
    • Grun, D. et al. Single-cell messenger RNA sequencing reveals rare intestinal cell types. Nature 525, 251-255 (2015).
    • (2015) Nature , vol.525 , pp. 251-255
    • Grun, D.1
  • 26
    • 84924565530 scopus 로고    scopus 로고
    • Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
    • Zeisel, A. et al. Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science 347, 1138-1142 (2015).
    • (2015) Science , vol.347 , pp. 1138-1142
    • Zeisel, A.1
  • 27
    • 84980325679 scopus 로고    scopus 로고
    • Div-Seq: Single-nucleus RNA-seq reveals dynamics of rare adult newborn neurons
    • Habib, N. et al. Div-Seq: single-nucleus RNA-seq reveals dynamics of rare adult newborn neurons. Science 353, 925-928 (2016).
    • (2016) Science , vol.353 , pp. 925-928
    • Habib, N.1
  • 28
    • 84900529199 scopus 로고    scopus 로고
    • Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
    • Treutlein, B. et al. Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature 509, 371-375 (2014).
    • (2014) Nature , vol.509 , pp. 371-375
    • Treutlein, B.1
  • 29
    • 84978761773 scopus 로고    scopus 로고
    • Resolving early mesoderm diversification through single-cell expression profiling
    • Scialdone, A. et al. Resolving early mesoderm diversification through single-cell expression profiling. Nature 535, 289-293 (2016).
    • (2016) Nature , vol.535 , pp. 289-293
    • Scialdone, A.1
  • 30
    • 85042366842 scopus 로고    scopus 로고
    • Mapping the mouse cell atlas by microwell-Seq
    • Han, X. et al. Mapping the mouse cell atlas by microwell-Seq. Cell 172, 1091-1107 (2018).
    • (2018) Cell , vol.172 , pp. 1091-1107
    • Han, X.1
  • 31
    • 85017360311 scopus 로고    scopus 로고
    • Scaling single-cell genomics from phenomenology to mechanism
    • Tanay, A. & Regev, A. Scaling single-cell genomics from phenomenology to mechanism. Nature 541, 331-338 (2017).
    • (2017) Nature , vol.541 , pp. 331-338
    • Tanay, A.1    Regev, A.2
  • 32
    • 85009113270 scopus 로고    scopus 로고
    • A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation
    • Nestorowa, S. et al. A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation. Blood 128, e20-e31 (2016).
    • (2016) Blood , vol.128 , pp. e20-e31
    • Nestorowa, S.1
  • 33
    • 84962050673 scopus 로고    scopus 로고
    • Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing
    • Drissen, R. et al. Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing. Nat. Immunol. 17, 666-676 (2016).
    • (2016) Nat. Immunol. , vol.17 , pp. 666-676
    • Drissen, R.1
  • 34
    • 84931394611 scopus 로고    scopus 로고
    • Identification of cDC1-and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
    • Schlitzer, A. et al. Identification of cDC1-and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow. Nat. Immunol. 16, 718-728 (2015).
    • (2015) Nat. Immunol. , vol.16 , pp. 718-728
    • Schlitzer, A.1
  • 35
    • 84989962489 scopus 로고    scopus 로고
    • Single-cell analysis of mixed-lineage states leading to a binary cell fate choice
    • Olsson, A. et al. Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature 537, 698-702 (2016).
    • (2016) Nature , vol.537 , pp. 698-702
    • Olsson, A.1
  • 36
    • 85027934223 scopus 로고    scopus 로고
    • Mapping the human DC lineage through the integration of high-dimensional techniques
    • See, P. et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science 356, eaag3009 (2017).
    • (2017) Science , vol.356 , pp. eaag3009
    • See, P.1
  • 37
    • 85015695567 scopus 로고    scopus 로고
    • Human haematopoietic stem cell lineage commitment is a continuous process
    • Velten, L. et al. Human haematopoietic stem cell lineage commitment is a continuous process. Nat. Cell Biol. 19, 271-281 (2017).
    • (2017) Nat. Cell Biol. , vol.19 , pp. 271-281
    • Velten, L.1
  • 38
    • 85042750225 scopus 로고    scopus 로고
    • Population snapshots predict early haematopoietic and erythroid hierarchies
    • Tusi, B. K. et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature 555, 54-60 (2018).
    • (2018) Nature , vol.555 , pp. 54-60
    • Tusi, B.K.1
  • 39
    • 85044760454 scopus 로고    scopus 로고
    • Molecular transitions in early progenitors during human cord blood hematopoiesis
    • Zheng, S., Papalexi, E., Butler, A., Stephenson, W. & Satija, R. Molecular transitions in early progenitors during human cord blood hematopoiesis. Mol. Syst. Biol. 14, e8041 (2018).
    • (2018) Mol. Syst. Biol. , vol.14 , pp. e8041
    • Zheng, S.1    Papalexi, E.2    Butler, A.3    Stephenson, W.4    Satija, R.5
  • 40
    • 84908125658 scopus 로고    scopus 로고
    • Clonal dynamics of native haematopoiesis
    • Sun, J. et al. Clonal dynamics of native haematopoiesis. Nature 514, 322-327 (2014).
    • (2014) Nature , vol.514 , pp. 322-327
    • Sun, J.1
  • 41
    • 85006269827 scopus 로고    scopus 로고
    • Dissecting immune circuits by linking CRISPR-pooled screens with single-cell RNA-seq
    • Jaitin, D. A. et al. Dissecting immune circuits by linking CRISPR-pooled screens with single-cell RNA-seq. Cell 167, 1883-1896 (2016).
    • (2016) Cell , vol.167 , pp. 1883-1896
    • Jaitin, D.A.1
  • 42
    • 0025797145 scopus 로고
    • Expression and function of c-kit in hemopoietic progenitor cells
    • Ogawa, M. et al. Expression and function of c-kit in hemopoietic progenitor cells. J. Exp. Med. 174, 63-71 (1991).
    • (1991) J. Exp. Med. , vol.174 , pp. 63-71
    • Ogawa, M.1
  • 43
    • 0028534860 scopus 로고
    • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison, S. J. & Weissman, I. L. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1, 661-673 (1994).
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 44
    • 15944363056 scopus 로고    scopus 로고
    • Identification of Lin-Sca1+ kit+ CD34+ Flt3-short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
    • Yang, L. et al. Identification of Lin-Sca1+ kit+ CD34+ Flt3-short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood 105, 2717-2723 (2005).
    • (2005) Blood , vol.105 , pp. 2717-2723
    • Yang, L.1
  • 45
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M. J. et al. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005).
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1
  • 46
    • 17844388346 scopus 로고    scopus 로고
    • Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior
    • Shojaei, F. et al. Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior. Dev. Cell 8, 651-663 (2005).
    • (2005) Dev. Cell , vol.8 , pp. 651-663
    • Shojaei, F.1
  • 47
    • 84899527626 scopus 로고    scopus 로고
    • Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors
    • Riddell, J. et al. Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell 157, 549-564 (2014).
    • (2014) Cell , vol.157 , pp. 549-564
    • Riddell, J.1
  • 48
    • 85018998005 scopus 로고    scopus 로고
    • Vitamin A-retinoic acid signaling regulates hematopoietic stem cell dormancy
    • Cabezas-Wallscheid, N. et al. Vitamin A-retinoic acid signaling regulates hematopoietic stem cell dormancy. Cell 169, 807-823 (2017).
    • (2017) Cell , vol.169 , pp. 807-823
    • Cabezas-Wallscheid, N.1
  • 49
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo, P. et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126, 755-766 (2006).
    • (2006) Cell , vol.126 , pp. 755-766
    • Laslo, P.1
  • 50
    • 34248199004 scopus 로고    scopus 로고
    • Bifurcation dynamics in lineagecommitment in bipotent progenitor cells
    • Huang, S., Guo, Y. P., May, G. & Enver, T. Bifurcation dynamics in lineagecommitment in bipotent progenitor cells. Dev. Biol. 305, 695-713 (2007).
    • (2007) Dev. Biol. , vol.305 , pp. 695-713
    • Huang, S.1    Guo, Y.P.2    May, G.3    Enver, T.4
  • 51
    • 85040442896 scopus 로고    scopus 로고
    • Clonal analysis of lineage fate in native haematopoiesis
    • Rodriguez-Fraticelli, A. E. et al. Clonal analysis of lineage fate in native haematopoiesis. Nature 553, 212-216 (2018).
    • (2018) Nature , vol.553 , pp. 212-216
    • Rodriguez-Fraticelli, A.E.1
  • 52
    • 0022419320 scopus 로고
    • The granulocyte-macrophage colony-stimulating factors
    • Metcalf, D. The granulocyte-macrophage colony-stimulating factors. Science 229, 16-22 (1985).
    • (1985) Science , vol.229 , pp. 16-22
    • Metcalf, D.1
  • 53
    • 0344336022 scopus 로고
    • In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor
    • Cohen, A. M. et al. In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor. Proc. Natl Acad. Sci. USA 84, 2484-2488 (1987).
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 2484-2488
    • Cohen, A.M.1
  • 54
    • 33644755502 scopus 로고    scopus 로고
    • Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors
    • Zhang, J. et al. Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors. Blood 107, 3600-3608 (2006).
    • (2006) Blood , vol.107 , pp. 3600-3608
    • Zhang, J.1
  • 55
    • 30344444770 scopus 로고    scopus 로고
    • A clonogenic bone marrow progenitor specific for macrophages and dendritic cells
    • Fogg, D. K. et al. A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science 311, 83-87 (2006).
    • (2006) Science , vol.311 , pp. 83-87
    • Fogg, D.K.1
  • 56
    • 35548970740 scopus 로고    scopus 로고
    • Identification of clonogenic common Flt3+ M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow
    • Onai, N. et al. Identification of clonogenic common Flt3+ M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow. Nat. Immunol. 8, 1207-1216 (2007).
    • (2007) Nat. Immunol. , vol.8 , pp. 1207-1216
    • Onai, N.1
  • 57
    • 44049097818 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues
    • Waskow, C. et al. The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat. Immunol. 9, 676-683 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 676-683
    • Waskow, C.1
  • 58
    • 0028136726 scopus 로고
    • Requirement of transcription factor PU. 1 in the development of multiple hematopoietic lineages
    • Scott, E. W., Simon, M. C., Anastasi, J. & Singh, H. Requirement of transcription factor PU. 1 in the development of multiple hematopoietic lineages. Science 265, 1573-1577 (1994).
    • (1994) Science , vol.265 , pp. 1573-1577
    • Scott, E.W.1    Simon, M.C.2    Anastasi, J.3    Singh, H.4
  • 59
    • 0032170972 scopus 로고    scopus 로고
    • Neutrophils deficient in PU. 1 do not terminally differentiate or become functionally competent
    • Anderson, K. L., Smith, K. A., Pio, F., Torbett, B. E. & Maki, R. A. Neutrophils deficient in PU. 1 do not terminally differentiate or become functionally competent. Blood 92, 1576-1585 (1998).
    • (1998) Blood , vol.92 , pp. 1576-1585
    • Anderson, K.L.1    Smith, K.A.2    Pio, F.3    Torbett, B.E.4    Maki, R.A.5
  • 60
    • 0242549003 scopus 로고    scopus 로고
    • Targeted disruption of the PU. 1 gene results in multiple hematopoietic abnormalities
    • McKercher, S. R. et al. Targeted disruption of the PU. 1 gene results in multiple hematopoietic abnormalities. EMBO J. 15, 5647-5658 (1996).
    • (1996) EMBO J. , vol.15 , pp. 5647-5658
    • McKercher, S.R.1
  • 61
    • 27644508638 scopus 로고    scopus 로고
    • Proteomic analysis of human neutrophil granules
    • Lominadze, G. et al. Proteomic analysis of human neutrophil granules. Mol. Cell Proteom. 4, 1503-1521 (2005).
    • (2005) Mol. Cell Proteom. , vol.4 , pp. 1503-1521
    • Lominadze, G.1
  • 62
    • 13544263218 scopus 로고    scopus 로고
    • The transcriptional program of terminal granulocytic differentiation
    • Theilgaard-Monch, K. et al. The transcriptional program of terminal granulocytic differentiation. Blood 105, 1785-1796 (2005).
    • (2005) Blood , vol.105 , pp. 1785-1796
    • Theilgaard-Monch, K.1
  • 63
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang, J. et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425, 836-841 (2003).
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1
  • 64
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Mendez-Ferrer, S. et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829-834 (2010).
    • (2010) Nature , vol.466 , pp. 829-834
    • Mendez-Ferrer, S.1
  • 65
    • 85006726063 scopus 로고    scopus 로고
    • Hematopoietic stem cell niches produce lineage-instructive signals to control multipotent progenitor differentiation
    • Cordeiro Gomes, A. et al. Hematopoietic stem cell niches produce lineage-instructive signals to control multipotent progenitor differentiation. Immunity 45, 1219-1231 (2016).
    • (2016) Immunity , vol.45 , pp. 1219-1231
    • Cordeiro Gomes, A.1
  • 66
    • 84952628356 scopus 로고    scopus 로고
    • Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
    • Haas, S. et al. Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors. Cell Stem Cell 17, 422-434 (2015).
    • (2015) Cell Stem Cell , vol.17 , pp. 422-434
    • Haas, S.1
  • 67
    • 66149115277 scopus 로고    scopus 로고
    • IFN? Activates dormant haematopoietic stem cells in vivo
    • Essers, M. A. et al. IFN? activates dormant haematopoietic stem cells in vivo. Nature 458, 904-908 (2009).
    • (2009) Nature , vol.458 , pp. 904-908
    • Essers, M.A.1
  • 69
    • 85041115553 scopus 로고    scopus 로고
    • Single-cell genomics: A stepping stone for future immunology discoveries
    • Giladi, A. & Amit, I. Single-cell genomics: a stepping stone for future immunology discoveries. Cell 172, 14-21 (2018).
    • (2018) Cell , vol.172 , pp. 14-21
    • Giladi, A.1    Amit, I.2
  • 70
    • 84953226880 scopus 로고    scopus 로고
    • BASiCS: Bayesian analysis of single-cell sequencing data
    • Vallejos, C. A., Marioni, J. C. & Richardson, S. BASiCS: Bayesian analysis of single-cell sequencing data. PLoS Comput. Biol. 11, e1004333 (2015).
    • (2015) PLoS Comput. Biol. , vol.11 , pp. e1004333
    • Vallejos, C.A.1    Marioni, J.C.2    Richardson, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.