Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

Science

Volumn 351, Issue 6269, 2016, Pages

  Notta, Faiyaz ^a,b,d   Zandi, Sasan ^a,b   Takayama, Naoya ^a,b   Dobson, Stephanie ^a,b   Gan, Olga I ^a   Wilson, Gavin ^b,d   Kaufmann, Kerstin B ^a,b   McLeod, Jessica ^a   Laurenti, Elisa ^f   Dunant, Cyrille F ^g   McPherson, John D ^c,d   Stein, Lincoln D ^b,d   Dror, Yigal ^e   Dick, John E ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^e HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BAH1 PROTEIN; CD135 ANTIGEN; CD14 ANTIGEN; CD15 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD45RA ANTIGEN; CD71 ANTIGEN; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IB ALPHA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 3; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; PROTEIN; SCF PROTEIN; THROMBOPOIETIN; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ADULT; BLOOD; BONE; CELLS AND CELL COMPONENTS; HIERARCHICAL SYSTEM; IDENTIFICATION METHOD; ONTOGENY; PROTEIN;

ADULT; ARTICLE; BONE MARROW; CELL COMPARTMENTALIZATION; CELL COUNT; CELL DIFFERENTIATION; CELL FATE; CELL FRACTIONATION; CELL HETEROGENEITY; CELL LINEAGE; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ERYTHROCYTE; ERYTHROPOIESIS; FETUS; FETUS LIVER; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN DEVELOPMENT; HUMAN TISSUE; IN VITRO STUDY; MEGAKARYOCYTE; MEGAKARYOCYTE ERYTHROID PROGENITOR; MULTIPOTENT STEM CELL; MYELOID PROGENITOR CELL; ONTOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; UMBILICAL CORD BLOOD; BONE MARROW CELL; CELL CULTURE; CELL SEPARATION; CYTOLOGY; EMBRYOLOGY; ERYTHROID CELL; FETUS BLOOD; GENE EXPRESSION PROFILING; GENETICS; LIVER; MEGAKARYOBLAST; PHYSIOLOGY;

ADULT; ANTIGENS, CD34; CELL LINEAGE; CELL SEPARATION; CELLS, CULTURED; ERYTHROID CELLS; FETAL BLOOD; GENE EXPRESSION PROFILING; HEMATOPOIESIS; HUMANS; LIVER; MEGAKARYOCYTE PROGENITOR CELLS; MEGAKARYOCYTES; MULTIPOTENT STEM CELLS; MYELOID CELLS; TRANSCRIPTION, GENETIC;

EID: 84955164174     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab2116     Document Type: Article

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