Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 22, 2018, Pages E5135-E5143

  Li, Wentao ^a   Hulswit, Ruben J G ^a   Kenney, Scott P ^b   Widjaja, Ivy ^a   Jung, Kwonil ^b   Alhamo, Moyasar A ^b   van Dieren, Brenda ^a   van Kuppeveld, Frank J M ^a   Saif, Linda J ^b   Bosch, Berend Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

APN; Cross species transmission; PDCoV; Receptor; Spike

Indexed keywords

AMINOPEPTIDASE; CELL SURFACE PROTEIN; VIRUS SPIKE PROTEIN; CORONAVIRUS SPIKE GLYCOPROTEIN; MICROSOMAL AMINOPEPTIDASE; VIRUS ANTIBODY;

ALPHACORONAVIRUS; ARTICLE; BIRD; CAT; CHICKEN; CONTROLLED STUDY; CORONAVIRINAE; CROSS SPECIES TRANSMISSION; ENZYME ACTIVE SITE; HOST RANGE; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; KNOCKOUT GENE; MAMMAL; NONHUMAN; PHYLOGENY; PIG; PORCINE DELTA CORONAVIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR BINDING; SPECIES DIVERSITY; VIRUS ENTRY; VIRUS IDENTIFICATION; VIRUS INFECTION; VIRUS TRANSMISSION; ANIMAL; CELL LINE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COMMUNICABLE DISEASE; CORONAVIRUS INFECTION; DOG; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; MDCK CELL LINE; METABOLISM; MOUSE; PATHOGENICITY; PHYSIOLOGY; TRANSMISSION; VERO CELL LINE; VETERINARY MEDICINE; VIROLOGY; ZOONOSIS;

ANIMALS; ANTIBODIES, VIRAL; CATS; CD13 ANTIGENS; CELL LINE; CERCOPITHECUS AETHIOPS; CHICKENS; COMMUNICABLE DISEASES, EMERGING; CORONAVIRUS; CORONAVIRUS INFECTIONS; DOGS; HOST SPECIFICITY; HOST-PATHOGEN INTERACTIONS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; MICE; SPIKE GLYCOPROTEIN, CORONAVIRUS; SWINE; VERO CELLS; ZOONOSES;

EID: 85047931538     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1802879115     Document Type: Article

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