Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

Nature

Volumn 531, Issue 7592, 2016, Pages 114-117

  Walls, Alexandra C ^a   Tortorici, M Alejandra ^b,c   Bosch, Berend Jan ^d   Frenz, Brandon ^a   Rottier, Peter J M ^d   DiMaio, Frank ^a   Rey, Félix A ^b,c   Veesler, David ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b INSTITUT PASTEUR   (France)

^c Institut Pasteur   (France)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORONAVIRUS SPIKE GLYCOPROTEIN; F PROTEIN; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS FUSION PROTEIN; VIRUS PROTEIN; VIRUS VACCINE;

ANTIBODY; CHEMICAL BINDING; DISEASE INCIDENCE; DRUG DEVELOPMENT; ELECTRON MICROSCOPY; MICROSTRUCTURE; MOLECULAR ANALYSIS; PNEUMONIA; PROTEIN; RODENT; VIRUS;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CORONAVIRIDAE; CRYOELECTRON MICROSCOPY; MOUSE; NONHUMAN; PARAMYXOVIRIDAE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CORONAVIRUS INFECTION; DROSOPHILA MELANOGASTER; IMMUNOLOGY; MOLECULAR GENETICS; MURINE HEPATITIS VIRUS; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE; VIROLOGY; VIRUS ENTRY;

CORONAVIRUS; PARAMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; CELL LINE; CORONAVIRUS INFECTIONS; CRYOELECTRON MICROSCOPY; DROSOPHILA MELANOGASTER; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURINE HEPATITIS VIRUS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRAL VACCINES; VIRUS INTERNALIZATION;

EID: 84960090603     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16988     Document Type: Article

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