-
1
-
-
0027479013
-
Aminopeptidases: Structure and function
-
Taylor, A. Aminopeptidases: Structure and function. FASEB J. 7, 290-298 (1993).
-
(1993)
FASEB J.
, vol.7
, pp. 290-298
-
-
Taylor, A.1
-
2
-
-
0027941838
-
Families of zinc metalloproteases
-
Hooper, N. M. Families of zinc metalloproteases. FEBS Lett. 354, 1-6 (1994).
-
(1994)
FEBS Lett.
, vol.354
, pp. 1-6
-
-
Hooper, N.M.1
-
3
-
-
48149111676
-
The moonlighting enzyme CD13: Old and new functions to target
-
Mina-Osorio, P. The moonlighting enzyme CD13: Old and new functions to target. Trends Mol. Med. 14, 361-371 (2008).
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 361-371
-
-
Mina-Osorio, P.1
-
4
-
-
0026729302
-
Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV
-
Delmas, B., et al. Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV. Nature 357, 417-420 (1992).
-
(1992)
Nature
, vol.357
, pp. 417-420
-
-
Delmas, B.1
-
5
-
-
0026693135
-
Human aminopeptidase N is a receptor for human coronavirus 229E
-
Yeager, C. L., et al. Human aminopeptidase N is a receptor for human coronavirus 229E. Nature 357, 420-422 (1992).
-
(1992)
Nature
, vol.357
, pp. 420-422
-
-
Yeager, C.L.1
-
6
-
-
0029100416
-
Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13
-
Fujii, H., et al. Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13. Clin. Exp. Metastasis 13, 337-344 (1995).
-
(1995)
Clin. Exp. Metastasis
, vol.13
, pp. 337-344
-
-
Fujii, H.1
-
7
-
-
0033950895
-
Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
-
Pasqualini, R., et al. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 60, 722-727 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 722-727
-
-
Pasqualini, R.1
-
8
-
-
16644386079
-
Role of aminopeptidase in angiogenesis
-
Sato, Y. Role of aminopeptidase in angiogenesis. Biol Pharm Bull 27, 772-776 (2004).
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 772-776
-
-
Sato, Y.1
-
9
-
-
42049114529
-
Aminopeptidase N in arterial hypertension
-
Danziger, R. S. Aminopeptidase N in arterial hypertension. Heart Fail. Rev. 13, 293-298 (2008).
-
(2008)
Heart Fail. Rev.
, vol.13
, pp. 293-298
-
-
Danziger, R.S.1
-
10
-
-
79951698213
-
Aminopeptidase N (CD13) as a target for cancer chemotherapy
-
Wickström, M., Larsson, R., Nygren, P., Gullbo, J. Aminopeptidase N (CD13) as a target for cancer chemotherapy. Cancer Science 102, 501-508 (2011).
-
(2011)
Cancer Science
, vol.102
, pp. 501-508
-
-
Wickström, M.1
Larsson, R.2
Nygren, P.3
Gullbo, J.4
-
11
-
-
34248359535
-
Impaired angiogenesis in aminopeptidase N-null mice
-
Rangel, R., et al. Impaired angiogenesis in aminopeptidase N-null mice. Proc. Natl. Acad. Sci. USA 104, 4588-4593 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4588-4593
-
-
Rangel, R.1
-
12
-
-
53449088574
-
The neovasculature homing motif NGR: More than meets the eye
-
Corti, A., Curnis, F., Arap, W., Pasqualini, R. The neovasculature homing motif NGR: More than meets the eye. Blood 112, 2628-2635 (2008).
-
(2008)
Blood
, vol.112
, pp. 2628-2635
-
-
Corti, A.1
Curnis, F.2
Arap, W.3
Pasqualini, R.4
-
13
-
-
77955471786
-
Novel aminopeptidase N (APN/CD13) inhibitor 24F can suppress invasion of hepatocellular carcinoma cells as well as angiogenesis
-
Inagaki, Y., et al. Novel aminopeptidase N (APN/CD13) inhibitor 24F can suppress invasion of hepatocellular carcinoma cells as well as angiogenesis. Biosci. Trends 4, 56-60 (2010).
-
(2010)
Biosci. Trends
, vol.4
, pp. 56-60
-
-
Inagaki, Y.1
-
14
-
-
33746317830
-
The molecular biology of coronaviruses
-
Masters, P. S. The molecular biology of coronaviruses. Adv. Virus Res. 66, 193-292 (2006).
-
(2006)
Adv. Virus Res.
, vol.66
, pp. 193-292
-
-
Masters, P.S.1
-
15
-
-
33846517378
-
Mutational analysis of aminopeptidase N, a receptor for several group 1 coronaviruses, identifies key determinants of viral host range
-
Tusell, S. M., Schittone, S. A., Holmes, K. V. Mutational analysis of aminopeptidase N, a receptor for several group 1 coronaviruses, identifies key determinants of viral host range. J. Virol. 81, 1261-1273 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 1261-1273
-
-
Tusell, S.M.1
Schittone, S.A.2
Holmes, K.V.3
-
16
-
-
84866168715
-
Structural bases of coronavirus attachment to host aminopeptidase n and its inhibition by neutralizing antibodies
-
Reguera, J., et al. Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies. PLoS Pathog. 8, e1002859, 10. 1371/journal. ppat. 1002859 (2012).
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1002859
-
-
Reguera, J.1
-
17
-
-
0025169919
-
Biosynthesis of intestinal microvillar proteins. Dimerization of aminopeptidase N and lactase-phlorizin hydrolase
-
Danielsen, E. M. Biosynthesis of intestinal microvillar proteins. Dimerization of aminopeptidase N and lactase-phlorizin hydrolase. Biochemistry 29, 305-308 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 305-308
-
-
Danielsen, E.M.1
-
18
-
-
0034473056
-
Structure and function of aminopeptidase N
-
Sjostrom, H., Noren, O., Olsen, J. Structure and function of aminopeptidase N. Adv Exp. Med. Biol. 477, 25-34 (2000).
-
(2000)
Adv Exp. Med. Biol.
, vol.477
, pp. 25-34
-
-
Sjostrom, H.1
Noren, O.2
Olsen, J.3
-
19
-
-
84868148624
-
The X-ray crystal structure of human aminopeptidase N reveals a novel dimer and the basis for peptide processing
-
Wong, A. H., Zhou, D., Rini, J. M. The X-ray crystal structure of human aminopeptidase N reveals a novel dimer and the basis for peptide processing. J. Biol. Chem. 287, 36804-36813 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36804-36813
-
-
Wong, A.H.1
Zhou, D.2
Rini, J.M.3
-
20
-
-
33748629692
-
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site
-
Addlagatta, A., Gay, L., Matthews, B. W. Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site. Proc. Natl. Acad. Sci. USA 103, 13339-13344 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13339-13344
-
-
Addlagatta, A.1
Gay, L.2
Matthews, B.W.3
-
21
-
-
84868122264
-
Structural basis for multifunctional roles of mammalian aminopeptidase N
-
Chen, L., Lin, Y.-L., Peng, G., Li, F. Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc. Natl. Acad. Sci. USA 109, 17966-17971 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 17966-17971
-
-
Chen, L.1
Lin, Y.-L.2
Peng, G.3
Li, F.4
-
22
-
-
84920569574
-
A structural view of coronavirus-receptor interactions
-
Reguera, J., Mudgal, G., Santiago, C., Casasnovas, J. M. A structural view of coronavirus-receptor interactions. Virus Res. 194, 3-15 (2014).
-
(2014)
Virus Res.
, vol.194
, pp. 3-15
-
-
Reguera, J.1
Mudgal, G.2
Santiago, C.3
Casasnovas, J.M.4
-
23
-
-
19544377390
-
Crystal structures of the tricorn interacting factor F3 from thermoplasma acidophilum, a zinc aminopeptidase in three different conformations
-
Kyrieleis, O. J. P., Goettig, P., Kiefersauer, R., Huber, R., Brandstetter, H. Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations. J. Mol. Biol. 349, 787-800 (2005).
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 787-800
-
-
Kyrieleis, O.J.P.1
Goettig, P.2
Kiefersauer, R.3
Huber, R.4
Brandstetter, H.5
-
24
-
-
79956348710
-
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
-
Kochan, G., et al. Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc. Natl. Acad. Sci. USA 108, 7745-7750 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7745-7750
-
-
Kochan, G.1
-
25
-
-
0030837334
-
Cryptic and regulatory epitopes in CD13/aminopeptidase N
-
Xu, Y., Wellner, D., Scheinberg, D. A. Cryptic and regulatory epitopes in CD13/aminopeptidase N. Exp. Hematol. 25, 521-529 (1997).
-
(1997)
Exp. Hematol.
, vol.25
, pp. 521-529
-
-
Xu, Y.1
Wellner, D.2
Scheinberg, D.A.3
-
26
-
-
84871256917
-
Development of Synthetic Aminopeptidase N/CD13 inhibitors to overcome cancer metastasis and angiogenesis
-
Su, L., et al. Development of Synthetic Aminopeptidase N/CD13 Inhibitors to Overcome Cancer Metastasis and Angiogenesis. ACS. Med. Chem. Lett. 3, 959-964 (2012).
-
(2012)
ACS. Med. Chem. Lett.
, vol.3
, pp. 959-964
-
-
Su, L.1
-
27
-
-
84875217801
-
Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy
-
Schmitt, C., et al. Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy. Bioorg. Med. Chem. 21, 2135-2144 (2013).
-
(2013)
Bioorg. Med. Chem.
, vol.21
, pp. 2135-2144
-
-
Schmitt, C.1
-
28
-
-
79955638487
-
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1
-
Nguyen, T. T., et al. Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat. Struct. Mol. Biol. 18, 604-613 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 604-613
-
-
Nguyen, T.T.1
-
29
-
-
33644875741
-
Aminopeptidase-N/CD13 (EC 3. 4. 11. 2) inhibitors: Chemistry, biological evaluations, and therapeutic prospects
-
Bauvois, B., Dauzonne, D. Aminopeptidase-N/CD13 (EC 3. 4. 11. 2) inhibitors: Chemistry, biological evaluations, and therapeutic prospects. Med. Res. Rev. 26, 88-130 (2006).
-
(2006)
Med. Res. Rev.
, vol.26
, pp. 88-130
-
-
Bauvois, B.1
Dauzonne, D.2
-
30
-
-
80052588946
-
A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13
-
Maiereanu, C., et al. A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13. Bioorg. Med. Chem. 19, 5716-5733 (2011).
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 5716-5733
-
-
Maiereanu, C.1
-
31
-
-
0028308336
-
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site
-
Delmas, B., et al. Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site. J. Virol. 68, 5216-5224 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 5216-5224
-
-
Delmas, B.1
-
32
-
-
84937433050
-
Exploring S1 plasticity and probing S1? Subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors
-
Revelant, G., et al. Exploring S1 plasticity and probing S1? subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors. Bioorg. Med. Chem. 23, 3192-3207 (2015).
-
(2015)
Bioorg. Med. Chem.
, vol.23
, pp. 3192-3207
-
-
Revelant, G.1
-
33
-
-
84936985808
-
MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model
-
Akita, S., et al. MT95-4, a fully humanized antibody raised against aminopeptidase N, reduces tumor progression in a mouse model. Cancer Sci. 106, 921-928 (2015).
-
(2015)
Cancer Sci.
, vol.106
, pp. 921-928
-
-
Akita, S.1
-
34
-
-
84879411842
-
Allosteric inhibition through suppression of transient conformational states
-
Tzeng, S.-R., Kalodimos, C. G. Allosteric inhibition through suppression of transient conformational states. Nat. Chem. Biol. 9, 462-465 (2013).
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 462-465
-
-
Tzeng, S.-R.1
Kalodimos, C.G.2
-
35
-
-
79955609648
-
Antigenic modules in the N-terminal S1 region of the Transmissible Gastroenteritis Virus spike protein
-
Reguera, J., Ordonõ, D., Santiago, C., Enjuanes, L., Casasnovas, J. M. Antigenic modules in the N-terminal S1 region of the Transmissible Gastroenteritis Virus spike protein. J. Gen. Virol. 92, 1117-1126 (2011).
-
(2011)
J. Gen. Virol.
, vol.92
, pp. 1117-1126
-
-
Reguera, J.1
Ordonõ, D.2
Santiago, C.3
Enjuanes, L.4
Casasnovas, J.M.5
-
37
-
-
0028103275
-
The CCP4 Suite: Programs for protein crystallography
-
Collaborative Computational Project N.
-
Collaborative Computational Project, N. The CCP4 Suite: Programs for Protein Crystallography. Acta Cryst. D50, 760-763 (1994).
-
(1994)
Acta Cryst. D
, vol.50
, pp. 760-763
-
-
-
38
-
-
0035788107
-
Pushing the boundaries of molecular replacement with maximum likelihood
-
Read, R. J. Pushing the boundaries of molecular replacement with maximum likelihood. Acta Cryst. D57, 1373-1382 (2001).
-
(2001)
Acta Cryst. D
, vol.57
, pp. 1373-1382
-
-
Read, R.J.1
-
39
-
-
70349602499
-
On the combination of molecular replacement and singlewavelength anomalous diffraction phasing for automated structure determination
-
Panjikar, S., Parthasarathy, V., Lamzin, V. S., Weiss, M. S., Tucker, P. A. On the combination of molecular replacement and singlewavelength anomalous diffraction phasing for automated structure determination. Acta Cryst. D65, 1089-1097 (2009).
-
(2009)
Acta Cryst. D
, vol.65
, pp. 1089-1097
-
-
Panjikar, S.1
Parthasarathy, V.2
Lamzin, V.S.3
Weiss, M.S.4
Tucker, P.A.5
-
40
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D., et al. PHENIX: A comprehensive Python-based system for macromolecular structure solution. Acta Cryst. D66, 213-221 (2010).
-
(2010)
Acta Cryst. D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
41
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P., Cowtan, K. Coot: Model-building tools for molecular graphics. Acta Cryst. D60, 2126-2132 (2004).
-
(2004)
Acta Cryst. D
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
|