-
1
-
-
84924271853
-
Global cancer statistics, 2012
-
Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, vJemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.
-
(2015)
CA Cancer J Clin
, vol.65
, Issue.2
, pp. 87-108
-
-
Torre, L.A.1
Bray, F.2
Siegel, R.L.3
Ferlay, J.4
Lortet-Tieulent, J.5
Vjemal, A.6
-
2
-
-
84890788843
-
The combination of chemotherapy and radiotherapy towards more efficient drug delivery
-
Cao W, Gu Y, Meineck M, Xu H. The combination of chemotherapy and radiotherapy towards more efficient drug delivery. Chem Asian J. 2014;9(1):48–57.
-
(2014)
Chem Asian J
, vol.9
, Issue.1
, pp. 48-57
-
-
Cao, W.1
Gu, Y.2
Meineck, M.3
Xu, H.4
-
3
-
-
84960104856
-
South Asian medicinal compounds as modulators of resistance to chemotherapy and radiotherapy
-
Prasad NR, Muthusamy G, Shanmugam M, Ambudkar SV. South Asian medicinal compounds as modulators of resistance to chemotherapy and radiotherapy. Cancers (Basel). 2016;8(3):E32.
-
(2016)
Cancers (Basel)
, vol.8
, Issue.3
-
-
Prasad, N.R.1
Muthusamy, G.2
Shanmugam, M.3
Ambudkar, S.V.4
-
4
-
-
84964490688
-
Cancer drug resistance. A brief overview from a genetic viewpoint
-
Rueff J, Rodrigues AS. Cancer drug resistance. A brief overview from a genetic viewpoint. Methods Mol Biol. 2016;1395:1–18.
-
(2016)
Methods Mol Biol
, vol.1395
, pp. 1-18
-
-
Rueff, J.1
Rodrigues, A.S.2
-
5
-
-
20544437870
-
Overview of tumor cell chemoresistance mechanisms
-
Gatti L, Zunino F. Overview of tumor cell chemoresistance mechanisms. Methods Mol Med. 2005;111:127–148.
-
(2005)
Methods Mol Med
, vol.111
, pp. 127-148
-
-
Gatti, L.1
Zunino, F.2
-
6
-
-
84942314013
-
Molecular mechanisms of drug resistance and its reversal in cancer
-
Kartal-Yandim M, Adan-Gokbulut A, Baran Y. Molecular mechanisms of drug resistance and its reversal in cancer. Crit Rev Biotechnol. 2016; 36(4):716–726.
-
(2016)
Crit Rev Biotechnol
, vol.36
, Issue.4
, pp. 716-726
-
-
Kartal-Yandim, M.1
Adan-Gokbulut, A.2
Baran, Y.3
-
7
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
Gottesman MM. Mechanisms of cancer drug resistance. Annu Rev Med. 2002;53(1):615–627.
-
(2002)
Annu Rev Med
, vol.53
, Issue.1
, pp. 615-627
-
-
Gottesman, M.M.1
-
8
-
-
84926328623
-
Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance
-
Verduzco D, Lloyd M, Xu L, et al. Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. PLoS One. 2015;10(3):e0120958.
-
(2015)
Plos One
, vol.10
, Issue.3
-
-
Verduzco, D.1
Lloyd, M.2
Xu, L.3
-
9
-
-
85014634179
-
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
-
Muz B, de la Puente P, Azab F, Azab AK. The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy. Hypoxia (Auckl). 2015;3:83–92.
-
(2015)
Hypoxia (Auckl)
, vol.3
, pp. 83-92
-
-
Muz, B.1
de la Puente, P.2
Azab, F.3
Azab, A.K.4
-
10
-
-
84876743991
-
Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma
-
Liang Y, Zheng T, Song R, et al. Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma. Hepatology. 2013;57(5):1847–1857.
-
(2013)
Hepatology
, vol.57
, Issue.5
, pp. 1847-1857
-
-
Liang, Y.1
Zheng, T.2
Song, R.3
-
11
-
-
85011807522
-
Advances in the targeting of HIF-1α and future therapeutic strategies for glioblastoma multiforme
-
Wang G, Wang JJ, Fu XL, Guang R, To ST. Advances in the targeting of HIF-1α and future therapeutic strategies for glioblastoma multiforme (review). Oncol Rep. 2017;37(2):657–670.
-
(2017)
(Review). Oncol Rep
, vol.37
, Issue.2
, pp. 657-670
-
-
Wang, G.1
Wang, J.J.2
Fu, X.L.3
Guang, R.4
To, S.T.5
-
12
-
-
77957601337
-
Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells
-
Ding Z, Yang L, Xie X, et al. Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glycoprotein in human colon carcinoma tissue and cells. J Cancer Res Clin Oncol. 2010;136(11): 1697–1707.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, Issue.11
, pp. 1697-1707
-
-
Ding, Z.1
Yang, L.2
Xie, X.3
-
13
-
-
84939789669
-
Structural integration in hypoxia-inducible factors
-
Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature. 2015;524(7565):303–308.
-
(2015)
Nature
, vol.524
, Issue.7565
, pp. 303-308
-
-
Wu, D.1
Potluri, N.2
Lu, J.3
Kim, Y.4
Rastinejad, F.5
-
14
-
-
85047775079
-
Expression and correlation of hypoxia inducible factor HIF-1α and HIF-2α in cervical carcinoma
-
Lixia J, Shaohua S, Qiaofa S, Feng L, Sijun L. Expression and correlation of hypoxia inducible factor HIF-1α and HIF-2α in cervical carcinoma. J Pract Med. 2012;28:1942–1943.
-
(2012)
J Pract Med
, vol.28
, pp. 1942-1943
-
-
Lixia, J.1
Shaohua, S.2
Qiaofa, S.3
Feng, L.4
Sijun, L.5
-
15
-
-
84881531075
-
Hypoxia-inducible factor-1alpha: Molecular-targeted therapy for hepatocellular carcinoma
-
Dong ZZ, Yao M, Wang L, Wu W, Gu X, Yao DF. Hypoxia-inducible factor-1alpha: molecular-targeted therapy for hepatocellular carcinoma. Mini Rev Med Chem. 2013;13(9):1295–1304.
-
(2013)
Mini Rev Med Chem
, vol.13
, Issue.9
, pp. 1295-1304
-
-
Dong, Z.Z.1
Yao, M.2
Wang, L.3
Wu, W.4
Gu, X.5
Yao, D.F.6
-
16
-
-
33846581569
-
Tumor hypoxia and targeted gene therapy
-
Greco O, Scott S. Tumor hypoxia and targeted gene therapy. Int Rev Cytol. 2007;257:181–212.
-
(2007)
Int Rev Cytol
, vol.257
, pp. 181-212
-
-
Greco, O.1
Scott, S.2
-
17
-
-
84926301332
-
The association between the rs11549465 polymorphism in the hif-1α gene and cancer risk: A meta-analysis
-
Li Y, Li C, Shi H, Lou L, Liu P. The association between the rs11549465 polymorphism in the hif-1α gene and cancer risk: a meta-analysis. Int J Clin Exp Med. 2015;8(2):1561–1574.
-
(2015)
Int J Clin Exp Med
, vol.8
, Issue.2
, pp. 1561-1574
-
-
Li, Y.1
Li, C.2
Shi, H.3
Lou, L.4
Liu, P.5
-
18
-
-
85047755549
-
Expression of hypoxia inducible factor-2 alpha in cervical squamous cell carcinoma and their clinical significance
-
Jiang LX, Shi QF, Shi SH, Li F, Liu SJ. Expression of hypoxia inducible factor-2 alpha in cervical squamous cell carcinoma and their clinical significance. Lab Med. 2012;27:819–821.
-
(2012)
Lab Med
, vol.27
, pp. 819-821
-
-
Jiang, L.X.1
Shi, Q.F.2
Shi, S.H.3
Li, F.4
Liu, S.J.5
-
19
-
-
84920856112
-
Hypoxia-inducible factor 1 and breast cancer metastasis
-
Liu ZJ, Semenza GL, Zhang HF. Hypoxia-inducible factor 1 and breast cancer metastasis. J Zhejiang Univ Sci B. 2015;16(1):32–43.
-
(2015)
J Zhejiang Univ Sci B
, vol.16
, Issue.1
, pp. 32-43
-
-
Liu, Z.J.1
Semenza, G.L.2
Zhang, H.F.3
-
20
-
-
84936804324
-
HIF-1α promotes epithelial-mesenchymal transition and metastasis through direct regulation of ZEB1 in colorectal cancer
-
Zhang W, Shi X, Peng Y, et al. HIF-1α promotes epithelial-mesenchymal transition and metastasis through direct regulation of ZEB1 in colorectal cancer. PLoS One. 2015;10(6):e0129603.
-
(2015)
Plos One
, vol.10
, Issue.6
-
-
Zhang, W.1
Shi, X.2
Peng, Y.3
-
21
-
-
84897542316
-
HIF-1 alpha overexpression correlates with poor overall survival and disease-free survival in gastric cancer patients post-gastrectomy
-
Chen L, Shi Y, Yuan J, et al. HIF-1 alpha overexpression correlates with poor overall survival and disease-free survival in gastric cancer patients post-gastrectomy. PLoS One. 2014;9(3):e90678.
-
(2014)
Plos One
, vol.9
, Issue.3
-
-
Chen, L.1
Shi, Y.2
Yuan, J.3
-
22
-
-
84938676098
-
HIF-1α in colorectal carcinoma: Review of the literature
-
Ioannou M, Paraskeva E, Baxevanidou K, et al. HIF-1α in colorectal carcinoma: review of the literature. J BUON. 2015;20(3):680–689.
-
(2015)
J BUON
, vol.20
, Issue.3
, pp. 680-689
-
-
Ioannou, M.1
Paraskeva, E.2
Baxevanidou, K.3
-
23
-
-
80051792973
-
HIF-1α in epidermis: Oxygen sensing, cutaneous angiogenesis, cancer, and non-cancer disorders
-
Rezvani HR, Ali N, Nissen LJ, et al. HIF-1α in epidermis: oxygen sensing, cutaneous angiogenesis, cancer, and non-cancer disorders. J Invest Dermatol. 2011;131(9):1793–1805.
-
(2011)
J Invest Dermatol
, vol.131
, Issue.9
, pp. 1793-1805
-
-
Rezvani, H.R.1
Ali, N.2
Nissen, L.J.3
-
24
-
-
84943141524
-
HIF-1α induces multidrug resistance in gastric cancer cells by inducing MiR-27a
-
Zhao Q, Li Y, Tan BB, Fan LQ, Yang PG, Tian Y. HIF-1α induces multidrug resistance in gastric cancer cells by inducing MiR-27a. PLoS One. 2015;10(8):e0132746.
-
(2015)
Plos One
, vol.10
, Issue.8
-
-
Zhao, Q.1
Li, Y.2
Tan, B.B.3
Fan, L.Q.4
Yang, P.G.5
Tian, Y.6
-
25
-
-
84903749390
-
Gemcitabine resistance is associated with epithelial-mesenchymal transition and induction of HIF-1α in pancreatic cancer cells
-
Wang R, Cheng L, Xia J, Wang Z, Wu Q, Wang Z. Gemcitabine resistance is associated with epithelial-mesenchymal transition and induction of HIF-1α in pancreatic cancer cells. Curr Cancer Drug Targets. 2014;14(4):407–417.
-
(2014)
Curr Cancer Drug Targets
, vol.14
, Issue.4
, pp. 407-417
-
-
Wang, R.1
Cheng, L.2
Xia, J.3
Wang, Z.4
Wu, Q.5
Wang, Z.6
-
26
-
-
84924351909
-
Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α
-
Gao H, Xie J, Peng J, et al. Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α. Exp Cell Res. 2015;332(2):236–246.
-
(2015)
Exp Cell Res
, vol.332
, Issue.2
, pp. 236-246
-
-
Gao, H.1
Xie, J.2
Peng, J.3
-
27
-
-
85012867872
-
Expression of hypoxia-inducible factor-1α affects tumor proliferation and antiapoptosis in surgically resected lung cancer
-
Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1α affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5(2):295–300.
-
(2016)
Mol Clin Oncol
, vol.5
, Issue.2
, pp. 295-300
-
-
Takasaki, C.1
Kobayashi, M.2
Ishibashi, H.3
Akashi, T.4
Okubo, K.5
-
28
-
-
84867514301
-
Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy
-
Meijer TW, Kaanders JH, Span PN, Bussink J. Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy. Clin Cancer Res. 2012;18(20):5585–5594.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.20
, pp. 5585-5594
-
-
Meijer, T.W.1
Kaanders, J.H.2
Span, P.N.3
Bussink, J.4
-
29
-
-
0038282482
-
The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy
-
Unruh A, Ressel A, Mohamed HG, et al. The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy. Oncogene. 2003;22(21): 3213–3220.
-
(2003)
Oncogene
, vol.22
, Issue.21
, pp. 3213-3220
-
-
Unruh, A.1
Ressel, A.2
Mohamed, H.G.3
-
30
-
-
84962254985
-
Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance
-
Feng H, Wang J, Chen W, et al. Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance. J Bone Oncol. 2016;5(2):67–73.
-
(2016)
J Bone Oncol
, vol.5
, Issue.2
, pp. 67-73
-
-
Feng, H.1
Wang, J.2
Chen, W.3
-
31
-
-
84901351747
-
Involvement of DNA damage response pathways in hepatocellular carcinoma
-
Yang SF, Chang CW, Wei RJ, Shiue YL, Wang SN, Yeh YT. Involvement of DNA damage response pathways in hepatocellular carcinoma. Biomed Res Int. 2014;1:153867.
-
(2014)
Biomed Res Int
, pp. 1
-
-
Yang, S.F.1
Chang, C.W.2
Wei, R.J.3
Shiue, Y.L.4
Wang, S.N.5
Yeh, Y.T.6
-
32
-
-
85006275578
-
Biomarkers of response and resistance to DNA repair targeted therapies
-
Stover EH, Konstantinopoulos PA, Matulonis UA, Swisher EM. Biomarkers of response and resistance to DNA repair targeted therapies. Clin Cancer Res. 2016;22(23):5651–5660.
-
(2016)
Clin Cancer Res
, vol.22
, Issue.23
, pp. 5651-5660
-
-
Stover, E.H.1
Konstantinopoulos, P.A.2
Matulonis, U.A.3
Swisher, E.M.4
-
33
-
-
84877923822
-
The response to DNA damage during differentiation: Pathways and consequences
-
Fortini P, Ferretti C, Dogliotti E. The response to DNA damage during differentiation: pathways and consequences. Mutat Res. 2013; 743–744(341):160–168.
-
(2013)
Mutat Res
, vol.743-744
, Issue.341
, pp. 160-168
-
-
Fortini, P.1
Ferretti, C.2
Dogliotti, E.3
-
34
-
-
84971517382
-
Targeting DNA damage response in the radio(Chemo)therapy of non-small cell lung cancer
-
Li L, Zhu T, Gao YF, et al. Targeting DNA damage response in the radio(chemo)therapy of non-small cell lung cancer. Int J Mol Sci. 2016; 17(6):E839.
-
(2016)
Int J Mol Sci
, vol.17
, Issue.6
, pp. 839
-
-
Li, L.1
Zhu, T.2
Gao, Y.F.3
-
35
-
-
3242776224
-
Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells
-
Um JH, Kang CD, Bae JH, et al. Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells. Exp Mol Med. 2004; 36(3):233–242.
-
(2004)
Exp Mol Med
, vol.36
, Issue.3
, pp. 233-242
-
-
Um, J.H.1
Kang, C.D.2
Bae, J.H.3
-
36
-
-
84864294365
-
HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer
-
Liu Y, Bernauer AM, Yingling CM, Belinsky SA. HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer. Carcinogenesis. 2012;33(6):1187–1192.
-
(2012)
Carcinogenesis
, vol.33
, Issue.6
, pp. 1187-1192
-
-
Liu, Y.1
Bernauer, A.M.2
Yingling, C.M.3
Belinsky, S.A.4
-
37
-
-
84879416094
-
HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia
-
Wrann S, Kaufmann MR, Wirthner R, Stiehl DP, Wenger RH. HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia. Biol Chem. 2013;394(4):519–528.
-
(2013)
Biol Chem
, vol.394
, Issue.4
, pp. 519-528
-
-
Wrann, S.1
Kaufmann, M.R.2
Wirthner, R.3
Stiehl, D.P.4
Wenger, R.H.5
-
38
-
-
84995460755
-
Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual targeting in patient-derived 3D pancreatic cancer models
-
Logsdon DP, Grimard M, Luo M, et al. Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: dual targeting in patient-derived 3D pancreatic cancer models. Mol Cancer Ther. 2016;15(11):2722–2732.
-
(2016)
Mol Cancer Ther
, vol.15
, Issue.11
, pp. 2722-2732
-
-
Logsdon, D.P.1
Grimard, M.2
Luo, M.3
-
39
-
-
85015998404
-
DNA damage players are linked to HIF-1α/hypoxia signaling
-
Rezaeian AH, Wang YH, Lin HK. DNA damage players are linked to HIF-1α/hypoxia signaling. Cell Cycle. 2017;16(8):725–726.
-
(2017)
Cell Cycle
, vol.16
, Issue.8
, pp. 725-726
-
-
Rezaeian, A.H.1
Wang, Y.H.2
Lin, H.K.3
-
40
-
-
57349157684
-
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts
-
Wirthner R, Wrann S, Balamurugan K, Wenger RH, Stiehl DP. Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts. Carcinogenesis. 2008;29(12):2306–2316.
-
(2008)
Carcinogenesis
, vol.29
, Issue.12
, pp. 2306-2316
-
-
Wirthner, R.1
Wrann, S.2
Balamurugan, K.3
Wenger, R.H.4
Stiehl, D.P.5
-
41
-
-
85028469699
-
Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors – a major reason for enhanced chemosensitivity?
-
Shenoy N, Dronca R, Quevedo F, et al. Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors – a major reason for enhanced chemosensitivity? Chin J Cancer Res. 2017; 29(4):374–378.
-
(2017)
Chin J Cancer Res
, vol.29
, Issue.4
, pp. 374-378
-
-
Shenoy, N.1
Dronca, R.2
Quevedo, F.3
-
42
-
-
84874844276
-
Radioprotective effect on HepG2 cells of low concentrations of cobalt chloride: Induction of hypoxia-inducible factor-1 alpha and clearance of reactive oxygen species
-
Jin W, Wang J, Xu S, et al. Radioprotective effect on HepG2 cells of low concentrations of cobalt chloride: induction of hypoxia-inducible factor-1 alpha and clearance of reactive oxygen species. J Radiat Res. 2012;54(2):203–209.
-
(2012)
J Radiat Res
, vol.54
, Issue.2
, pp. 203-209
-
-
Jin, W.1
Wang, J.2
Xu, S.3
-
43
-
-
84890020112
-
Application of two-dimensional gel-based mass spectrometry to functionally dissect resistance to targeted cancer therapy
-
Klein O, Rohwer N, de Molina KF, et al. Application of two-dimensional gel-based mass spectrometry to functionally dissect resistance to targeted cancer therapy. Proteomics Clin Appl. 2013;7(11–12):813–824.
-
(2013)
Proteomics Clin Appl
, vol.7
, Issue.11-12
, pp. 813-824
-
-
Klein, O.1
Rohwer, N.2
de Molina, K.F.3
-
44
-
-
84904437150
-
Hypoxia enhances the radioresistance of mouse mesenchymal stromal cells
-
Sugrue T, Lowndes NF, Ceredig R. Hypoxia enhances the radioresistance of mouse mesenchymal stromal cells. Stem Cells. 2014;32(8): 2188–2200.
-
(2014)
Stem Cells
, vol.32
, Issue.8
, pp. 2188-2200
-
-
Sugrue, T.1
Lowndes, N.F.2
Ceredig, R.3
-
45
-
-
85038222811
-
The typical metabolic modifiers conferring improvement in cancer resistance
-
Tan W, Zhong Z, Wang S, et al. The typical metabolic modifiers conferring improvement in cancer resistance. Curr Med Chem. 2017;24(34): 3698–3710.
-
(2017)
Curr Med Chem
, vol.24
, Issue.34
, pp. 3698-3710
-
-
Tan, W.1
Zhong, Z.2
Wang, S.3
-
46
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4(11):891–899.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.11
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
47
-
-
84864875404
-
A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo
-
Liu Y, Cao Y, Zhang W, et al. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Mol Cancer Ther. 2012; 11(8):1672–1682.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.8
, pp. 1672-1682
-
-
Liu, Y.1
Cao, Y.2
Zhang, W.3
-
48
-
-
80052845698
-
Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer
-
Lu CW, Lin SC, Chien CW, et al. Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer. Am J Pathol. 2011;179(3):1405–1414.
-
(2011)
Am J Pathol
, vol.179
, Issue.3
, pp. 1405-1414
-
-
Lu, C.W.1
Lin, S.C.2
Chien, C.W.3
-
49
-
-
77649094375
-
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol
-
Zhou M, Zhao Y, Ding Y, et al. Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol. Mol Cancer. 2010;9:33.
-
(2010)
Mol Cancer
, vol.9
, pp. 33
-
-
Zhou, M.1
Zhao, Y.2
Ding, Y.3
-
50
-
-
84867140008
-
Emerging roles of PKM2 in cell metabolism and cancer progression
-
Luo W, Semenza GL. Emerging roles of PKM2 in cell metabolism and cancer progression. Trends Endocrinol Metab. 2012;23(11):560–566.
-
(2012)
Trends Endocrinol Metab
, vol.23
, Issue.11
, pp. 560-566
-
-
Luo, W.1
Semenza, G.L.2
-
51
-
-
84879356157
-
Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells
-
Huang CY, Kuo WT, Huang YC, Lee TC, Yu LC. Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells. Cell Death Dis. 2013;4:e622.
-
(2013)
Cell Death Dis
, vol.4
-
-
Huang, C.Y.1
Kuo, W.T.2
Huang, Y.C.3
Lee, T.C.4
Yu, L.C.5
-
52
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim J, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006;3(3):177–185.
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 177-185
-
-
Kim, J.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
53
-
-
84934293579
-
Metabolic signature identifies novel targets for drug resistance in multiple myeloma
-
Maiso P, Huynh D, Moschetta M, et al. Metabolic signature identifies novel targets for drug resistance in multiple myeloma. Cancer Res. 2015;75(10):2071–2082.
-
(2015)
Cancer Res
, vol.75
, Issue.10
, pp. 2071-2082
-
-
Maiso, P.1
Huynh, D.2
Moschetta, M.3
-
55
-
-
84937635983
-
The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors
-
Zhao J, Feng D, Yang L, Shen G, Zheng F, Xu B. The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors. Cancer Treat Rev. 2015;41(7):623–633.
-
(2015)
Cancer Treat Rev
, vol.41
, Issue.7
, pp. 623-633
-
-
Zhao, J.1
Feng, D.2
Yang, L.3
Shen, G.4
Zheng, F.5
Xu, B.6
-
56
-
-
77954341696
-
Survival signalling and apoptosis resistance in glioblastomas: Opportunities for targeted therapeutics
-
Krakstad C, Chekenya M. Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer. 2010;9(1):135.
-
(2010)
Mol Cancer
, vol.9
, Issue.1
, pp. 135
-
-
Krakstad, C.1
Chekenya, M.2
-
57
-
-
84928539179
-
Broad targeting of resistance to apoptosis in cancer
-
Mohammad RM, Muqbil I, Lowe L, et al. Broad targeting of resistance to apoptosis in cancer. Semin Cancer Biol. 2015;35(Suppl):S78–S103.
-
(2015)
Semin Cancer Biol
, vol.35
, pp. SS78-S103
-
-
Mohammad, R.M.1
Muqbil, I.2
Lowe, L.3
-
58
-
-
84899584147
-
HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells
-
Nishimoto A, Kugimiya N, Hosoyama T, Enoki T, Li TS, Hamano K. HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells. Int J Oncol. 2014;44(6):2077–2084.
-
(2014)
Int J Oncol
, vol.44
, Issue.6
, pp. 2077-2084
-
-
Nishimoto, A.1
Kugimiya, N.2
Hosoyama, T.3
Enoki, T.4
Li, T.S.5
Hamano, K.6
-
59
-
-
77957786826
-
Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB
-
Rohwer N, Dame C, Haugstetter A, et al. Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB. PLoS One. 2010;5(8):e12038.
-
(2010)
Plos One
, vol.5
, Issue.8
-
-
Rohwer, N.1
Dame, C.2
Haugstetter, A.3
-
60
-
-
84959340136
-
Enhancement of drug sensitivity by knockdown of HIF-1α in gastric carcinoma cells
-
Zhao Q, Tan BB, Li Y, Fan LQ, Yang PG, Tian Y. Enhancement of drug sensitivity by knockdown of HIF-1α in gastric carcinoma cells. Oncol Res. 2016;23:129–136.
-
(2016)
Oncol Res
, vol.23
, pp. 129-136
-
-
Zhao, Q.1
Tan, B.B.2
Li, Y.3
Fan, L.Q.4
Yang, P.G.5
Tian, Y.6
-
61
-
-
73449110126
-
Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism
-
Pei GT, Wu CW, Lin WW. Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism. Biochem Biophys Res Commun. 2010;391(2): 1274–1279.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, Issue.2
, pp. 1274-1279
-
-
Pei, G.T.1
Wu, C.W.2
Lin, W.W.3
-
62
-
-
77953699668
-
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
-
Dalby KN, Tekedereli I, Lopez-Berestein G, Ozpolat B. Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy. 2010;6(3):322–329.
-
(2010)
Autophagy
, vol.6
, Issue.3
, pp. 322-329
-
-
Dalby, K.N.1
Tekedereli, I.2
Lopez-Berestein, G.3
Ozpolat, B.4
-
63
-
-
84976619676
-
MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt–mTOR signaling pathway
-
Song L, Liu S, Liang Z, et al. MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt–mTOR signaling pathway. Tumour Biol. 2016;37(9):12161–12168.
-
(2016)
Tumour Biol
, vol.37
, Issue.9
, pp. 12161-12168
-
-
Song, L.1
Liu, S.2
Liang, Z.3
-
64
-
-
84937638028
-
Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells
-
Fang Y, Tan J, Zhang Q. Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells. Cell Biol Int. 2015; 39(8):891–898.
-
(2015)
Cell Biol Int
, vol.39
, Issue.8
, pp. 891-898
-
-
Fang, Y.1
Tan, J.2
Zhang, Q.3
-
65
-
-
80054087824
-
Mitochondrial ROS generation for regulation of autophagic pathways in cancer
-
Li ZY, Yang Y, Ming M, Liu B. Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem Biophys Res Commun. 2011;414(1):5–8.
-
(2011)
Biochem Biophys Res Commun
, vol.414
, Issue.1
, pp. 5-8
-
-
Li, Z.Y.1
Yang, Y.2
Ming, M.3
Liu, B.4
-
66
-
-
85019783963
-
Hypoxia-induced autophagy in tumor cells: A key target for improving cancer immunotherapy
-
Paggetti J, Viry E, Berchem G, Moussay E, Janji B. Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy. Cancer Cell Microenviron. 2014;1:e213.
-
(2014)
Cancer Cell Microenviron
, vol.1
, pp. 213
-
-
Paggetti, J.1
Viry, E.2
Berchem, G.3
Moussay, E.4
Janji, B.5
-
67
-
-
84925044445
-
Role of autophagy in head and neck cancer and therapeutic resistance
-
Sannigrahi MK, Singh V, Sharma R, Panda NK, Khullar M. Role of autophagy in head and neck cancer and therapeutic resistance. Oral Dis. 2015;21(3):283–291.
-
(2015)
Oral Dis
, vol.21
, Issue.3
, pp. 283-291
-
-
Sannigrahi, M.K.1
Singh, V.2
Sharma, R.3
Panda, N.K.4
Khullar, M.5
-
68
-
-
85014069382
-
Targeting autophagy in cancer stem cells as an anticancer therapy
-
Lei Y, Zhang D, Yu J, Dong H, Zhang J, Yang S. Targeting autophagy in cancer stem cells as an anticancer therapy. Cancer Lett. 2017;393: 33–39.
-
(2017)
Cancer Lett
, vol.393
, pp. 33-39
-
-
Lei, Y.1
Zhang, D.2
Yu, J.3
Dong, H.4
Zhang, J.5
Yang, S.6
-
69
-
-
84884812963
-
Targeting autophagy as a potential therapeutic approach for melanoma therapy
-
Liu H, He Z, Simon HU. Targeting autophagy as a potential therapeutic approach for melanoma therapy. Semin Cancer Bio. 2013;23(5): 352–360.
-
(2013)
Semin Cancer Bio
, vol.23
, Issue.5
, pp. 352-360
-
-
Liu, H.1
He, Z.2
Simon, H.U.3
-
70
-
-
84918583818
-
Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells
-
Sun Y, Xing X, Liu Q, et al. Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells. Int J Oncol. 2015;46(2):750–756.
-
(2015)
Int J Oncol
, vol.46
, Issue.2
, pp. 750-756
-
-
Sun, Y.1
Xing, X.2
Liu, Q.3
-
71
-
-
84937854099
-
Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells
-
Wu HM, Jiang ZF, Ding PS, Shao LJ, Liu RY. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep. 2015;5:12291.
-
(2015)
Sci Rep
, vol.5
-
-
Wu, H.M.1
Jiang, Z.F.2
Ding, P.S.3
Shao, L.J.4
Liu, R.Y.5
-
72
-
-
84919599130
-
Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells
-
Zou YM, Hu GY, Zhao XQ, et al. Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells. J Huazhong Univ Sci Technolog Med Sci. 2014; 34(5):761–767.
-
(2014)
J Huazhong Univ Sci Technolog Med Sci
, vol.34
, Issue.5
, pp. 761-767
-
-
Zou, Y.M.1
Hu, G.Y.2
Zhao, X.Q.3
-
73
-
-
84957991436
-
Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells
-
Jeong JK, Gurunathan S, Kang MH, et al. Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells. Sci Rep. 2016;6:21688.
-
(2016)
Sci Rep
, vol.6
-
-
Jeong, J.K.1
Gurunathan, S.2
Kang, M.H.3
-
74
-
-
85019750440
-
Hypoxia-inducible factor 1 α protects mesenchymal stem cells against oxygen-glucose deprivation-induced injury via autophagy induction and PI3K/AKT/mTOR signaling pathway
-
Lv B, Hua T, Li F, et al. Hypoxia-inducible factor 1 α protects mesenchymal stem cells against oxygen-glucose deprivation-induced injury via autophagy induction and PI3K/AKT/mTOR signaling pathway. Am J Transl Res. 2017;9(5):2492–2499.
-
(2017)
Am J Transl Res
, vol.9
, Issue.5
, pp. 2492-2499
-
-
Lv, B.1
Hua, T.2
Li, F.3
|