MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt-mTOR signaling pathway

Tumor Biology

Volumn 37, Issue 9, 2016, Pages 12161-12168

  Song, Lili ^a   Liu, Shikai ^a   Zhang, Liang ^a   Yao, Hairong ^a   Gao, Fangyuan ^a   Xu, Dongkui ^a   Li, Qian ^a  

^a CANGZHOU CENTRAL HOSPITAL   (China)

Author keywords

Cervical cancer; HIF 1 ; miR 21; Radiosensitivity

Indexed keywords

CISPLATIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; HIF1A PROTEIN, HUMAN; MICRORNA; MIRN21 MICRORNA, HUMAN; MTOR PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOPHAGY; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; POLYMERASE CHAIN REACTION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; UPREGULATION; UTERINE CERVIX CANCER; WESTERN BLOTTING; PATHOLOGY; PHYSIOLOGY; RADIATION TOLERANCE; UTERINE CERVICAL NEOPLASMS;

AUTOPHAGY; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RADIATION TOLERANCE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UTERINE CERVICAL NEOPLASMS;

EID: 84976619676     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-016-5073-3     Document Type: Article

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