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Volumn 34, Issue 5, 2014, Pages 761-767

Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells

Author keywords

autophagy; Beclin 1; hypoxia; radioresistance

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; GREEN FLUORESCENT PROTEIN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIGHT CHAIN 3, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN C JUN;

EID: 84919599130     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-014-1349-2     Document Type: Article
Times cited : (38)

References (25)
  • 1
    • 77957564889 scopus 로고    scopus 로고
    • Hypoxia in models of lung cancer: implications for targeted therapeutics
    • PID: 20858837, COI: 1:CAS:528:DC%2BC3cXht1aktbnP
    • Graves EE, Vilalta M, Cecic IK, et al. Hypoxia in models of lung cancer: implications for targeted therapeutics. Clin Cancer Res, 2010, 16(19):4843–4852
    • (2010) Clin Cancer Re , vol.16 , Issue.19 , pp. 4843-4852
    • Graves, E.E.1    Vilalta, M.2    Cecic, I.K.3
  • 2
    • 84883501150 scopus 로고    scopus 로고
    • HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
    • PID: 23999440, COI: 1:CAS:528:DC%2BC3sXhsVenu7bJ
    • Semenza GL. HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations. J Clin Invest, 2013, 123(9):3664–3671
    • (2013) J Clin Inves , vol.123 , Issue.9 , pp. 3664-3671
    • Semenza, G.L.1
  • 3
    • 77956934514 scopus 로고    scopus 로고
    • HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia
    • PID: 20637870
    • Liu XW, Su Y, Zhu H, et al. HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia. Pharmacol Res, 2010, 62(5):416–425
    • (2010) Pharmacol Re , vol.62 , Issue.5 , pp. 416-425
    • Liu, X.W.1    Su, Y.2    Zhu, H.3
  • 4
    • 58549084773 scopus 로고    scopus 로고
    • Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrest
    • PID: 18710819, COI: 1:CAS:528:DC%2BD1MXhtVejtbs%3D
    • Yoshiba S, Ito D, Nagumo T, et al. Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrest. Oral Oncol, 2009, 45(2):109–115
    • (2009) Oral Onco , vol.45 , Issue.2 , pp. 109-115
    • Yoshiba, S.1    Ito, D.2    Nagumo, T.3
  • 5
    • 33748458071 scopus 로고    scopus 로고
    • Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene
    • PID: 16532342, COI: 1:CAS:528:DC%2BD28XptVGqsL0%3D
    • Song X, Liu X, Chi W, et al. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene. Cancer Chemother Pharmacol, 2006, 58(6):776–784
    • (2006) Cancer Chemother Pharmaco , vol.58 , Issue.6 , pp. 776-784
    • Song, X.1    Liu, X.2    Chi, W.3
  • 6
    • 33645735151 scopus 로고    scopus 로고
    • The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha
    • PID: 16585195, COI: 1:CAS:528:DC%2BD28XjtVOrtrY%3D
    • Dayan F, Roux D, Brahimi-Horn MC, et al. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha. Cancer Res, 2006, 66(7):3688–3698
    • (2006) Cancer Re , vol.66 , Issue.7 , pp. 3688-3698
    • Dayan, F.1    Roux, D.2    Brahimi-Horn, M.C.3
  • 7
    • 65949103633 scopus 로고    scopus 로고
    • HAF: the new player in oxygenindependent HIF-1alpha degradation
    • PID: 19377289, COI: 1:CAS:528:DC%2BD1MXmvFCiur4%3D
    • Koh MY, Powis G. HAF: the new player in oxygenindependent HIF-1alpha degradation. Cell Cycle, 2009, 8(9): 1359–1366
    • (2009) Cell Cycl , vol.8 , Issue.9 , pp. 1359-1366
    • Koh, M.Y.1    Powis, G.2
  • 8
    • 84884820652 scopus 로고    scopus 로고
    • Regulation of autophagy by stress-responsive transcription factors
    • PID: 23726895, COI: 1:CAS:528:DC%2BC3sXpsV2ntbo%3D
    • Pietrocola F, Izzo V, Niso-Santano M, et al. Regulation of autophagy by stress-responsive transcription factors. Semin Cancer Biol, 2013, 23(5):310–322
    • (2013) Semin Cancer Bio , vol.23 , Issue.5 , pp. 310-322
    • Pietrocola, F.1    Izzo, V.2    Niso-Santano, M.3
  • 9
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: crosstalk between autophagy and apoptosis
    • PID: 17717517, COI: 1:CAS:528:DC%2BD2sXpsVartb8%3D
    • Maiuri MC, Zalckvar E, Kimchi A, et al. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol, 2007, 8(9):741–752
    • (2007) Nat Rev Mol Cell Bio , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3
  • 10
    • 66349121718 scopus 로고    scopus 로고
    • Hypoxiainduced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
    • PID: 19273585, COI: 1:CAS:528:DC%2BD1MXlvFSqu70%3D
    • Bellot G, Garcia-Medina R, Gounon P, et al. Hypoxiainduced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol, 2009, 29(10):2570–2781
    • (2009) Mol Cell Bio , vol.29 , Issue.10 , pp. 2570-2781
    • Bellot, G.1    Garcia-Medina, R.2    Gounon, P.3
  • 11
    • 60149098492 scopus 로고    scopus 로고
    • The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
    • PID: 19060920, COI: 1:CAS:528:DC%2BD1cXhsVKlt73K
    • Li DD, Wang LL, Deng R, et al. The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene, 2009, 28(6):886–898
    • (2009) Oncogen , vol.28 , Issue.6 , pp. 886-898
    • Li, D.D.1    Wang, L.L.2    Deng, R.3
  • 12
    • 84899713732 scopus 로고    scopus 로고
    • Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function
    • PID: 24787293, COI: 1:CAS:528:DC%2BC2cXns1Clur4%3D
    • Martinez-Outschoorn U, Sotgia F, Lisanti MP. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function. Semin Oncol, 2014, 41(2):195–216
    • (2014) Semin Onco , vol.41 , Issue.2 , pp. 195-216
    • Martinez-Outschoorn, U.1    Sotgia, F.2    Lisanti, M.P.3
  • 13
    • 84966192535 scopus 로고
    • The histological structure of some human lung cancers and the possible implications for radiotherapy
    • PID: 13304213, COI: 1:STN:280:DyaG28%2Fls1Gltg%3D%3D
    • Thomlinson RH, Gray LH. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer, 1955, 9(4):539–549
    • (1955) Br J Cance , vol.9 , Issue.4 , pp. 539-549
    • Thomlinson, R.H.1    Gray, L.H.2
  • 14
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • PID: 15170446, COI: 1:CAS:528:DC%2BD2cXksVaisbs%3D
    • Brown JM, Wilson WR. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer, 2004, 4(6):437–447
    • (2004) Nat Rev Cance , vol.4 , Issue.6 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 15
    • 84902968221 scopus 로고    scopus 로고
    • The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment
    • PID: 24420150, COI: 1:CAS:528:DC%2BC2cXntlOkt70%3D
    • Ye J, Wu D, Wu P, et al. The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment. Tumour Biol, 2014, 35(5):3945–3951
    • (2014) Tumour Bio , vol.35 , Issue.5 , pp. 3945-3951
    • Ye, J.1    Wu, D.2    Wu, P.3
  • 16
    • 0027285380 scopus 로고
    • p53 mutations increase resistance to ionizing radiation
    • PID: 8516323, COI: 1:CAS:528:DyaK3sXksVKru7s%3D
    • Lee JM, Bernstein A. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA, 1993, 90(12):5742–5746
    • (1993) Proc Natl Acad Sci US , vol.90 , Issue.12 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 17
    • 77951228508 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: cell death or cell survival?
    • PID: 20022734, COI: 1:CAS:528:DC%2BC3cXks1Srtb8%3D
    • Mazure NM, Pouyssegur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol, 2010, 22(2):177–180
    • (2010) Curr Opin Cell Bio , vol.22 , Issue.2 , pp. 177-180
    • Mazure, N.M.1    Pouyssegur, J.2
  • 18
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • PID: 20965422, COI: 1:CAS:528:DC%2BC3cXhtlCjtr%2FM
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell, 2010, 40(2):280–293
    • (2010) Mol Cel , vol.40 , Issue.2 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 19
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules
    • PID: 15144951, COI: 1:CAS:528:DC%2BD2cXksFCmt7k%3D
    • Moeller BJ, Cao Y, Li CY, et al. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell, 2004, 5(5):429–441
    • (2004) Cancer Cel , vol.5 , Issue.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3
  • 20
    • 64149112403 scopus 로고    scopus 로고
    • The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors
    • PID: 19098000, COI: 1:CAS:528:DC%2BD1MXhvVSntLs%3D
    • Harada H, Itasaka S, Kizaka-Kondoh S, et al. The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors. J Biol Chem, 2009, 284(8):5332–5342
    • (2009) J Biol Che , vol.284 , Issue.8 , pp. 5332-5342
    • Harada, H.1    Itasaka, S.2    Kizaka-Kondoh, S.3
  • 21
    • 84882665806 scopus 로고    scopus 로고
    • p63, Sharp1, and HIFs: master regulators of metastasis in triple-negative breast cancer
    • PID: 23913939, COI: 1:CAS:528:DC%2BC3sXht1OisrbO
    • Piccolo S, Enzo E, Montagner M. p63, Sharp1, and HIFs: master regulators of metastasis in triple-negative breast cancer. Cancer Res, 2013, 73(16):4978–4981
    • (2013) Cancer Re , vol.73 , Issue.16 , pp. 4978-4981
    • Piccolo, S.1    Enzo, E.2    Montagner, M.3
  • 22
    • 0036139795 scopus 로고    scopus 로고
    • HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases
    • PID: 11795593, COI: 1:CAS:528:DC%2BD38Xmt12ktA%3D%3D
    • Michiels C, Minet E, Michel G, et al. HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases. IUBMB Life, 2001, 52(1–2):49–53
    • (2001) IUBMB Lif , vol.52 , Issue.1-2 , pp. 49-53
    • Michiels, C.1    Minet, E.2    Michel, G.3
  • 23
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP
    • COI: 1:CAS:528:DC%2BD3MXjtFynt7c%3D
    • Yamashita K, Discher DJ, Hu J, et al. Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP. J Biol Chem, 2001, 276(16):126 45–12 653
    • (2001) J Biol Che , vol.276 , Issue.16 , pp. 126 45-12 653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3
  • 24
    • 4544346656 scopus 로고    scopus 로고
    • JunD reduces tumor angiogenesis by protecting cells from oxidative stress
    • PID: 15369676, COI: 1:CAS:528:DC%2BD2cXnvFehtbk%3D
    • Gerald D, Berra E, Frapart YM, et al. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell, 2004, 118(6):781–794
    • (2004) Cel , vol.118 , Issue.6 , pp. 781-794
    • Gerald, D.1    Berra, E.2    Frapart, Y.M.3
  • 25
    • 84884332903 scopus 로고    scopus 로고
    • The variability of autophagy and cell death susceptibility: Unanswered questions
    • PID: 23846383, COI: 1:CAS:528:DC%2BC2cXktF2rtL4%3D
    • Loos B, Engelbrecht AM, Lockshin RA, et al. The variability of autophagy and cell death susceptibility: Unanswered questions. Autophagy, 2013, 9(9):1270–1285
    • (2013) Autophag , vol.9 , Issue.9 , pp. 1270-1285
    • Loos, B.1    Engelbrecht, A.M.2    Lockshin, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.