-
1
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
Alexander A, Cai SL, Kim J et al (2010). ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci USA 107: 4153-4158.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
-
3
-
-
0035881870
-
Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29
-
Bauvy C, Gane P, Arico S, Codogno P, Ogier-Denis E (2001). Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29. Exp Cell Res 268: 139-149.
-
(2001)
Exp Cell Res
, vol.268
, pp. 139-149
-
-
Bauvy, C.1
Gane, P.2
Arico, S.3
Codogno, P.4
Ogier-Denis, E.5
-
4
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K, Tsuruta A, Selak MA et al (2006). TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126: 107-120.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
-
5
-
-
79551550094
-
Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases
-
Bodily JM, Mehta KP, Laimins LA (2011). Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases. Cancer Res 71: 1187-1195.
-
(2011)
Cancer Res
, vol.71
, pp. 1187-1195
-
-
Bodily, J.M.1
Mehta, K.P.2
Laimins, L.A.3
-
6
-
-
10044276783
-
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
-
Brugarolas J, Lei K, Hurley RL et al (2004). Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev 18: 2893-2904.
-
(2004)
Genes Dev
, vol.18
, pp. 2893-2904
-
-
Brugarolas, J.1
Lei, K.2
Hurley, R.L.3
-
7
-
-
48449101433
-
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
-
Budanov AV, Karin M (2008). p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 134: 451-460.
-
(2008)
Cell
, vol.134
, pp. 451-460
-
-
Budanov, A.V.1
Karin, M.2
-
8
-
-
0029741890
-
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
-
Bursch W, Ellinger A, Kienzl H et al (1996). Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 17: 1595-1607.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1595-1607
-
-
Bursch, W.1
Ellinger, A.2
Kienzl, H.3
-
9
-
-
51849084360
-
The PTEN-PI3K pathway: of feedbacks and cross-talks
-
Carracedo A, Pandolfi PP (2008). The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene 27: 5527-5541.
-
(2008)
Oncogene
, vol.27
, pp. 5527-5541
-
-
Carracedo, A.1
Pandolfi, P.P.2
-
10
-
-
79960629010
-
HDAC2 promotes cell migration/invasion abilities through HIF-1alpha stabilization in human oral squamous cell carcinoma
-
Chang CC, Lin BR, Chen ST, Hsieh TH, Li YJ, Kuo MY (2011). HDAC2 promotes cell migration/invasion abilities through HIF-1alpha stabilization in human oral squamous cell carcinoma. J Oral Pathol Med 40: 567-575.
-
(2011)
J Oral Pathol Med
, vol.40
, pp. 567-575
-
-
Chang, C.C.1
Lin, B.R.2
Chen, S.T.3
Hsieh, T.H.4
Li, Y.J.5
Kuo, M.Y.6
-
11
-
-
84873305194
-
Knockdown of beta-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines
-
Chang HW, Lee YS, Nam HY et al (2013). Knockdown of beta-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines. Cell Signal 25: 839-847.
-
(2013)
Cell Signal
, vol.25
, pp. 839-847
-
-
Chang, H.W.1
Lee, Y.S.2
Nam, H.Y.3
-
12
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, Kim HP, Sciurba FC et al (2008). Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS ONE 3: e3316.
-
(2008)
PLoS ONE
, vol.3
-
-
Chen, Z.H.1
Kim, H.P.2
Sciurba, F.C.3
-
13
-
-
78650434097
-
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
-
Chen ZH, Lam HC, Jin Y et al (2010). Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci USA 107: 18880-18885.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18880-18885
-
-
Chen, Z.H.1
Lam, H.C.2
Jin, Y.3
-
14
-
-
84855465861
-
Role of human papillomavirus infection in carcinogenesis of oral squamous cell carcinoma with evidences of prognostic association
-
Chen SF, Yu FS, Chang YC, Fu E, Nieh S, Lin YS (2012). Role of human papillomavirus infection in carcinogenesis of oral squamous cell carcinoma with evidences of prognostic association. J Oral Pathol Med 41: 9-15.
-
(2012)
J Oral Pathol Med
, vol.41
, pp. 9-15
-
-
Chen, S.F.1
Yu, F.S.2
Chang, Y.C.3
Fu, E.4
Nieh, S.5
Lin, Y.S.6
-
15
-
-
77955714496
-
Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma
-
Claerhout S, Verschooten L, Van Kelst S et al (2010). Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma. Int J Cancer 127: 2790-2803.
-
(2010)
Int J Cancer
, vol.127
, pp. 2790-2803
-
-
Claerhout, S.1
Verschooten, L.2
Van Kelst, S.3
-
16
-
-
0036681293
-
Overexpression of Bcl-2 in squamous cell carcinoma of the larynx: a marker of radioresistance
-
Condon LT, Ashman JN, Ell SR, Stafford ND, Greenman J, Cawkwell L (2002). Overexpression of Bcl-2 in squamous cell carcinoma of the larynx: a marker of radioresistance. Int J Cancer 100: 472-475.
-
(2002)
Int J Cancer
, vol.100
, pp. 472-475
-
-
Condon, L.T.1
Ashman, J.N.2
Ell, S.R.3
Stafford, N.D.4
Greenman, J.5
Cawkwell, L.6
-
17
-
-
77956230830
-
BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway
-
Cosse JP, Rommelaere G, Ninane N, Arnould T, Michiels C (2010). BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway. Biochem Pharmacol 80: 1160-1169.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1160-1169
-
-
Cosse, J.P.1
Rommelaere, G.2
Ninane, N.3
Arnould, T.4
Michiels, C.5
-
18
-
-
77954680626
-
DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation
-
Craig AL, Holcakova J, Finlan LE et al (2010). DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Mol cancer 9: 195.
-
(2010)
Mol cancer
, vol.9
, pp. 195
-
-
Craig, A.L.1
Holcakova, J.2
Finlan, L.E.3
-
19
-
-
77950516104
-
mTOR signaling and drug development in cancer
-
Dancey J (2010). mTOR signaling and drug development in cancer. Nat Rev Clin Oncol 7: 209-219.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 209-219
-
-
Dancey, J.1
-
20
-
-
84873080242
-
Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes
-
Griffin LM, Cicchini L, Pyeon D (2013). Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes. Virology 437: 12-19.
-
(2013)
Virology
, vol.437
, pp. 12-19
-
-
Griffin, L.M.1
Cicchini, L.2
Pyeon, D.3
-
21
-
-
78349269485
-
Human pyruvate kinase M2: a multifunctional protein
-
Gupta V, Bamezai RN (2010). Human pyruvate kinase M2: a multifunctional protein. Protein Sci 19: 2031-2044.
-
(2010)
Protein Sci
, vol.19
, pp. 2031-2044
-
-
Gupta, V.1
Bamezai, R.N.2
-
22
-
-
35148818453
-
Long-term alcohol ingestion alters the folate-binding kinetics in intestinal brush border membrane in experimental alcoholism
-
Hamid A, Kaur J (2007). Long-term alcohol ingestion alters the folate-binding kinetics in intestinal brush border membrane in experimental alcoholism. Alcohol 41: 441-446.
-
(2007)
Alcohol
, vol.41
, pp. 441-446
-
-
Hamid, A.1
Kaur, J.2
-
23
-
-
1342310142
-
DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene
-
Harrigan JA, Vezina CM, McGarrigle BP et al (2004). DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene. Toxicol Sci 77: 307-314.
-
(2004)
Toxicol Sci
, vol.77
, pp. 307-314
-
-
Harrigan, J.A.1
Vezina, C.M.2
McGarrigle, B.P.3
-
24
-
-
74949113519
-
Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure
-
Huang Y, Chuang AY, Romano RA et al (2010). Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure. Cell Cycle 9: 328-338.
-
(2010)
Cell Cycle
, vol.9
, pp. 328-338
-
-
Huang, Y.1
Chuang, A.Y.2
Romano, R.A.3
-
25
-
-
84863344601
-
Phospho-DeltaNp63alpha-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
-
Huang Y, Guerrero-Preston R, Ratovitski EA (2012). Phospho-DeltaNp63alpha-dependent regulation of autophagic signaling through transcription and micro-RNA modulation. Cell Cycle 11: 1247-1259.
-
(2012)
Cell Cycle
, vol.11
, pp. 1247-1259
-
-
Huang, Y.1
Guerrero-Preston, R.2
Ratovitski, E.A.3
-
26
-
-
84885186911
-
Prognostic significance of Beclin-1 expression in laryngeal squamous cell carcinoma
-
Huang L, Wang S, Li SS, Yang XM (2013). Prognostic significance of Beclin-1 expression in laryngeal squamous cell carcinoma. Pathol Oncol Res 19: 771-777.
-
(2013)
Pathol Oncol Res
, vol.19
, pp. 771-777
-
-
Huang, L.1
Wang, S.2
Li, S.S.3
Yang, X.M.4
-
27
-
-
77954623119
-
Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD
-
Hwang JW, Chung S, Sundar IK et al (2010). Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys 500: 203-209.
-
(2010)
Arch Biochem Biophys
, vol.500
, pp. 203-209
-
-
Hwang, J.W.1
Chung, S.2
Sundar, I.K.3
-
28
-
-
78650396000
-
Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma
-
Jerhammar F, Ceder R, Garvin S, Grenman R, Grafstrom RC, Roberg K (2010). Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma. Cancer Biol Ther 10: 1244-1251.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 1244-1251
-
-
Jerhammar, F.1
Ceder, R.2
Garvin, S.3
Grenman, R.4
Grafstrom, R.C.5
Roberg, K.6
-
29
-
-
0030883558
-
Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells
-
Jia L, Dourmashkin RR, Allen PD, Gray AB, Newland AC, Kelsey SM (1997). Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells. Br J Haematol 98: 673-685.
-
(1997)
Br J Haematol
, vol.98
, pp. 673-685
-
-
Jia, L.1
Dourmashkin, R.R.2
Allen, P.D.3
Gray, A.B.4
Newland, A.C.5
Kelsey, S.M.6
-
30
-
-
33748188459
-
Epidermal growth factor receptor biology in head and neck cancer
-
Kalyankrishna S, Grandis JR (2006). Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 24: 2666-2672.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2666-2672
-
-
Kalyankrishna, S.1
Grandis, J.R.2
-
31
-
-
53549090696
-
Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1
-
Kim HP, Wang X, Chen ZH et al (2008). Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy 4: 887-895.
-
(2008)
Autophagy
, vol.4
, pp. 887-895
-
-
Kim, H.P.1
Wang, X.2
Chen, Z.H.3
-
32
-
-
79960007748
-
Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy
-
Kuwahara Y, Oikawa T, Ochiai Y et al (2011). Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy. Cell Death Dis 2: e177.
-
(2011)
Cell Death Dis
, vol.2
-
-
Kuwahara, Y.1
Oikawa, T.2
Ochiai, Y.3
-
33
-
-
54249104991
-
Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model
-
Lambert LA, Qiao N, Hunt KK et al (2008). Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model. Cancer Res 68: 7966-7974.
-
(2008)
Cancer Res
, vol.68
, pp. 7966-7974
-
-
Lambert, L.A.1
Qiao, N.2
Hunt, K.K.3
-
34
-
-
77957112423
-
The prognostic significance of p16 overexpression in oropharyngeal squamous cell carcinoma: implications for treatment strategies and future clinical studies
-
Langendijk JA, Psyrri A (2010). The prognostic significance of p16 overexpression in oropharyngeal squamous cell carcinoma: implications for treatment strategies and future clinical studies. Ann Oncol 21: 1931-1934.
-
(2010)
Ann Oncol
, vol.21
, pp. 1931-1934
-
-
Langendijk, J.A.1
Psyrri, A.2
-
36
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M et al (1999). Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
37
-
-
78049317160
-
Autophagy induction by the 30-100 kDa fraction of areca nut in both normal and malignant cells through reactive oxygen species
-
Lin MH, Hsieh WF, Chiang WF et al (2010a). Autophagy induction by the 30-100 kDa fraction of areca nut in both normal and malignant cells through reactive oxygen species. Oral Oncol 46: 822-828.
-
(2010)
Oral Oncol
, vol.46
, pp. 822-828
-
-
Lin, M.H.1
Hsieh, W.F.2
Chiang, W.F.3
-
38
-
-
77955923224
-
Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy
-
Lin TY, Chang JT, Wang HM et al (2010b). Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy. Int J Radiat Oncol Biol Phys 78: 246-256.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, pp. 246-256
-
-
Lin, T.Y.1
Chang, J.T.2
Wang, H.M.3
-
39
-
-
79952244140
-
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
-
Liu D, Yang Y, Liu Q, Wang J (2011). Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells. Med Oncol 28: 105-111.
-
(2011)
Med Oncol
, vol.28
, pp. 105-111
-
-
Liu, D.1
Yang, Y.2
Liu, Q.3
Wang, J.4
-
41
-
-
12244302198
-
Squamous cell carcinoma of the oral cavity in patients aged 45 years and under: a descriptive analysis of 116 cases diagnosed in the South East of England from 1990 to 1997
-
Llewellyn CD, Linklater K, Bell J, Johnson NW, Warnakulasuriya KA (2003). Squamous cell carcinoma of the oral cavity in patients aged 45 years and under: a descriptive analysis of 116 cases diagnosed in the South East of England from 1990 to 1997. Oral Oncol 39: 106-114.
-
(2003)
Oral Oncol
, vol.39
, pp. 106-114
-
-
Llewellyn, C.D.1
Linklater, K.2
Bell, J.3
Johnson, N.W.4
Warnakulasuriya, K.A.5
-
42
-
-
79952084155
-
Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells
-
Macha MA, Matta A, Chauhan SS, Siu KW, Ralhan R (2011). Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells. PLoS ONE 6: e14728.
-
(2011)
PLoS ONE
, vol.6
-
-
Macha, M.A.1
Matta, A.2
Chauhan, S.S.3
Siu, K.W.4
Ralhan, R.5
-
44
-
-
73549101691
-
Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy
-
Martin AP, Mitchell C, Rahmani M, Nephew KP, Grant S, Dent P (2009). Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy. Cancer Biol Ther 8: 2084-2096.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 2084-2096
-
-
Martin, A.P.1
Mitchell, C.2
Rahmani, M.3
Nephew, K.P.4
Grant, S.5
Dent, P.6
-
45
-
-
59549098296
-
The human papillomavirus E7 oncoprotein
-
McLaughlin-Drubin ME, Munger K (2009). The human papillomavirus E7 oncoprotein. Virology 384: 335-344.
-
(2009)
Virology
, vol.384
, pp. 335-344
-
-
McLaughlin-Drubin, M.E.1
Munger, K.2
-
46
-
-
47249165575
-
Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens
-
Mishra NC, Rir-Sima-Ah J, Langley RJ et al (2008). Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J Immunol 180: 7655-7663.
-
(2008)
J Immunol
, vol.180
, pp. 7655-7663
-
-
Mishra, N.C.1
Rir-Sima-Ah, J.2
Langley, R.J.3
-
47
-
-
77956394519
-
Overexpression of p63 is associated with radiation resistance and prognosis in oral squamous cell carcinoma
-
Moergel M, Abt E, Stockinger M, Kunkel M (2010). Overexpression of p63 is associated with radiation resistance and prognosis in oral squamous cell carcinoma. Oral Oncol 46: 667-671.
-
(2010)
Oral Oncol
, vol.46
, pp. 667-671
-
-
Moergel, M.1
Abt, E.2
Stockinger, M.3
Kunkel, M.4
-
48
-
-
84875892111
-
Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease
-
Murrow L, Debnath J (2013). Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease. Annu Rev Pathol 8: 105-137.
-
(2013)
Annu Rev Pathol
, vol.8
, pp. 105-137
-
-
Murrow, L.1
Debnath, J.2
-
49
-
-
79960836823
-
Cyclin D as a therapeutic target in cancer
-
Musgrove EA, Caldon CE, Barraclough J, Stone A, Sutherland RL (2011). Cyclin D as a therapeutic target in cancer. Nat Rev Cancer 11: 558-572.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 558-572
-
-
Musgrove, E.A.1
Caldon, C.E.2
Barraclough, J.3
Stone, A.4
Sutherland, R.L.5
-
50
-
-
84880891210
-
Radioresistant cancer cells can be conditioned to enter senescence by mTOR inhibition
-
Nam HY, Han MW, Chang HW et al (2013). Radioresistant cancer cells can be conditioned to enter senescence by mTOR inhibition. Cancer Res 73: 4267-4277.
-
(2013)
Cancer Res
, vol.73
, pp. 4267-4277
-
-
Nam, H.Y.1
Han, M.W.2
Chang, H.W.3
-
51
-
-
33947235680
-
Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer
-
Nathan CO, Amirghahari N, Rong X et al (2007). Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer. Cancer Res 67: 2160-2168.
-
(2007)
Cancer Res
, vol.67
, pp. 2160-2168
-
-
Nathan, C.O.1
Amirghahari, N.2
Rong, X.3
-
52
-
-
0036347157
-
Oral cancer and precancerous lesions
-
Neville BW, Day TA (2002). Oral cancer and precancerous lesions. CA Cancer J Clin 52: 195-215.
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 195-215
-
-
Neville, B.W.1
Day, T.A.2
-
53
-
-
56249119507
-
Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis
-
Nomura H, Uzawa K, Yamano Y et al (2009). Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis. Hum Pathol 40: 83-91.
-
(2009)
Hum Pathol
, vol.40
, pp. 83-91
-
-
Nomura, H.1
Uzawa, K.2
Yamano, Y.3
-
54
-
-
79955676537
-
Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
-
O'Donovan TR, O'Sullivan GC, McKenna SL (2011). Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7: 509-524.
-
(2011)
Autophagy
, vol.7
, pp. 509-524
-
-
O'Donovan, T.R.1
O'Sullivan, G.C.2
McKenna, S.L.3
-
55
-
-
61449417240
-
Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy
-
Pae HO, Lee YC, Chung HT (2008). Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy. Recent Pat Inflammation Allergy Drug Discovery 2: 159-165.
-
(2008)
Recent Pat Inflammation Allergy Drug Discovery
, vol.2
, pp. 159-165
-
-
Pae, H.O.1
Lee, Y.C.2
Chung, H.T.3
-
56
-
-
0035863399
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
-
Paglin S, Hollister T, Delohery T et al (2001). A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 61: 439-444.
-
(2001)
Cancer Res
, vol.61
, pp. 439-444
-
-
Paglin, S.1
Hollister, T.2
Delohery, T.3
-
57
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X et al (2005). Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
58
-
-
84881539307
-
HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression
-
Philip B, Ito K, Moreno-Sanchez R, Ralph SJ (2013). HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression. Carcinogenesis 34: 1699-1707.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1699-1707
-
-
Philip, B.1
Ito, K.2
Moreno-Sanchez, R.3
Ralph, S.J.4
-
59
-
-
37349055876
-
TP53 mutations and survival in squamous-cell carcinoma of the head and neck
-
Poeta ML, Manola J, Goldwasser MA et al (2007). TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N Engl J Med 357: 2552-2561.
-
(2007)
N Engl J Med
, vol.357
, pp. 2552-2561
-
-
Poeta, M.L.1
Manola, J.2
Goldwasser, M.A.3
-
60
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G et al (2003). Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Investig 112: 1809-1820.
-
(2003)
J Clin Investig
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
62
-
-
79151474526
-
DeltaNp63alpha/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure
-
Ratovitski EA (2011). DeltaNp63alpha/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure. Arch Biochem Biophys 506: 208-215.
-
(2011)
Arch Biochem Biophys
, vol.506
, pp. 208-215
-
-
Ratovitski, E.A.1
-
63
-
-
0035872475
-
A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains
-
Redon R, Muller D, Caulee K, Wanherdrick K, Abecassis J, du Manoir S (2001). A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains. Cancer Res 61: 4122-4129.
-
(2001)
Cancer Res
, vol.61
, pp. 4122-4129
-
-
Redon, R.1
Muller, D.2
Caulee, K.3
Wanherdrick, K.4
Abecassis, J.5
du Manoir, S.6
-
64
-
-
9144272266
-
Risk factors for oral and pharyngeal cancer in young adults
-
Rodriguez T, Altieri A, Chatenoud L et al (2004). Risk factors for oral and pharyngeal cancer in young adults. Oral Oncol 40: 207-213.
-
(2004)
Oral Oncol
, vol.40
, pp. 207-213
-
-
Rodriguez, T.1
Altieri, A.2
Chatenoud, L.3
-
65
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop KM, van den Beucken T, Dubois L et al (2010). The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Investig 120: 127-141.
-
(2010)
J Clin Investig
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.1
van den Beucken, T.2
Dubois, L.3
-
66
-
-
0031740497
-
Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
-
Sano T, Oyama T, Kashiwabara K, Fukuda T, Nakajima T (1998). Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 153: 1741-1748.
-
(1998)
Am J Pathol
, vol.153
, pp. 1741-1748
-
-
Sano, T.1
Oyama, T.2
Kashiwabara, K.3
Fukuda, T.4
Nakajima, T.5
-
67
-
-
34249284421
-
Nitrosamines as nicotinic receptor ligands
-
Schuller HM (2007). Nitrosamines as nicotinic receptor ligands. Life Sci 80: 2274-2280.
-
(2007)
Life Sci
, vol.80
, pp. 2274-2280
-
-
Schuller, H.M.1
-
68
-
-
8344242220
-
Autophagy in health and disease: a double-edged sword
-
Shintani T, Klionsky DJ (2004). Autophagy in health and disease: a double-edged sword. Science 306: 990-995.
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
69
-
-
32644444748
-
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus
-
Smeets SJ, Braakhuis BJ, Abbas S et al (2006). Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus. Oncogene 25: 2558-2564.
-
(2006)
Oncogene
, vol.25
, pp. 2558-2564
-
-
Smeets, S.J.1
Braakhuis, B.J.2
Abbas, S.3
-
70
-
-
77956024826
-
The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis
-
Spangle JM, Munger K (2010). The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. J Virol 84: 9398-9407.
-
(2010)
J Virol
, vol.84
, pp. 9398-9407
-
-
Spangle, J.M.1
Munger, K.2
-
71
-
-
67349186983
-
How cigarette smoke skews immune responses to promote infection, lung disease and cancer
-
Stampfli MR, Anderson GP (2009). How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nat Rev Immunol 9: 377-384.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 377-384
-
-
Stampfli, M.R.1
Anderson, G.P.2
-
72
-
-
84887437596
-
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
-
Sui X, Chen R, Wang Z et al (2013). Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis 4: e838.
-
(2013)
Cell Death Dis
, vol.4
, pp. e838
-
-
Sui, X.1
Chen, R.2
Wang, Z.3
-
73
-
-
67651017972
-
Beclin1 induces autophagy and its potential contributions to sensitizes SiHa cells to carboplatin therapy
-
Sun Y, Zhang J, Peng ZL (2009). Beclin1 induces autophagy and its potential contributions to sensitizes SiHa cells to carboplatin therapy. Int J Gynecol Cancer 19: 772-776.
-
(2009)
Int J Gynecol Cancer
, vol.19
, pp. 772-776
-
-
Sun, Y.1
Zhang, J.2
Peng, Z.L.3
-
74
-
-
84874716169
-
Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy
-
Surviladze Z, Sterk RT, DeHaro SA, Ozbun MA (2013). Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy. J Virol 87: 2508-2517.
-
(2013)
J Virol
, vol.87
, pp. 2508-2517
-
-
Surviladze, Z.1
Sterk, R.T.2
DeHaro, S.A.3
Ozbun, M.A.4
-
75
-
-
0032513114
-
The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells
-
Talis AL, Huibregtse JM, Howley PM (1998). The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J Biol Chem 273: 6439-6445.
-
(1998)
J Biol Chem
, vol.273
, pp. 6439-6445
-
-
Talis, A.L.1
Huibregtse, J.M.2
Howley, P.M.3
-
76
-
-
2442505482
-
Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors
-
Toussaint-Smith E, Donner DB, Roman A (2004). Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors. Oncogene 23: 2988-2995.
-
(2004)
Oncogene
, vol.23
, pp. 2988-2995
-
-
Toussaint-Smith, E.1
Donner, D.B.2
Roman, A.3
-
77
-
-
79952281987
-
The frequent co-expression of the oncogenes PIK3CA and PAK1 in oral carcinomas
-
Tu HF, Chang KW, Chiang WF et al (2011). The frequent co-expression of the oncogenes PIK3CA and PAK1 in oral carcinomas. Oral Oncol 47: 211-216.
-
(2011)
Oral Oncol
, vol.47
, pp. 211-216
-
-
Tu, H.F.1
Chang, K.W.2
Chiang, W.F.3
-
78
-
-
80055033312
-
Targeting fibroblast growth factor receptor 3 enhances radiosensitivity in human squamous cancer cells
-
Uzawa K, Ishigami T, Fushimi K et al (2011). Targeting fibroblast growth factor receptor 3 enhances radiosensitivity in human squamous cancer cells. Oncogene 30: 4447-4452.
-
(2011)
Oncogene
, vol.30
, pp. 4447-4452
-
-
Uzawa, K.1
Ishigami, T.2
Fushimi, K.3
-
79
-
-
67650885510
-
Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab
-
Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA (2009). Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab. PLoS ONE 4: e6251.
-
(2009)
PLoS ONE
, vol.4
, pp. e6251
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
80
-
-
79251578964
-
Hypoxia-induced autophagic response is associated with aggressive phenotype and elevated incidence of metastasis in orthotopic immunocompetent murine models of head and neck squamous cell carcinomas (HNSCC)
-
Vigneswaran N, Wu J, Song A, Annapragada A, Zacharias W (2011). Hypoxia-induced autophagic response is associated with aggressive phenotype and elevated incidence of metastasis in orthotopic immunocompetent murine models of head and neck squamous cell carcinomas (HNSCC). Exp Mol Pathol 90: 215-225.
-
(2011)
Exp Mol Pathol
, vol.90
, pp. 215-225
-
-
Vigneswaran, N.1
Wu, J.2
Song, A.3
Annapragada, A.4
Zacharias, W.5
-
81
-
-
77955432889
-
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma
-
Voss V, Senft C, Lang V et al (2010). The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res 8: 1002-1016.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1002-1016
-
-
Voss, V.1
Senft, C.2
Lang, V.3
-
82
-
-
79952276580
-
Heme oxygenase-1 in tumor biology and therapy
-
Was H, Dulak J, Jozkowicz A (2010). Heme oxygenase-1 in tumor biology and therapy. Curr Drug Targets 11: 1551-1570.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 1551-1570
-
-
Was, H.1
Dulak, J.2
Jozkowicz, A.3
-
83
-
-
77957688352
-
The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy
-
Wei Y, Kadia T, Tong W et al (2010). The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy. Autophagy 6: 976-978.
-
(2010)
Autophagy
, vol.6
, pp. 976-978
-
-
Wei, Y.1
Kadia, T.2
Tong, W.3
-
84
-
-
77953229918
-
Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy
-
Wu WK, Sakamoto KM, Milani M et al (2010a). Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy. Drug Resist Updat 13: 87-92.
-
(2010)
Drug Resist Updat
, vol.13
, pp. 87-92
-
-
Wu, W.K.1
Sakamoto, K.M.2
Milani, M.3
-
85
-
-
77953383616
-
Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors
-
Wu Z, Chang PC, Yang JC et al (2010b). Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer 1: 40-49.
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
Chang, P.C.2
Yang, J.C.3
-
86
-
-
84872772327
-
Deguelin induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells
-
Yang YL, Ji C, Bi ZG et al (2013). Deguelin induces both apoptosis and autophagy in cultured head and neck squamous cell carcinoma cells. PLoS ONE 8: e54736.
-
(2013)
PLoS ONE
, vol.8
-
-
Yang, Y.L.1
Ji, C.2
Bi, Z.G.3
-
87
-
-
84870864069
-
The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4
-
Zang Y, Thomas SM, Chan ET et al (2012). The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4. Autophagy 8: 1873-1874.
-
(2012)
Autophagy
, vol.8
, pp. 1873-1874
-
-
Zang, Y.1
Thomas, S.M.2
Chan, E.T.3
-
88
-
-
67549101188
-
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
-
Zhang J, Ney PA (2009). Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ 16: 939-946.
-
(2009)
Cell Death Differ
, vol.16
, pp. 939-946
-
-
Zhang, J.1
Ney, P.A.2
-
89
-
-
45749087722
-
Head and neck cancer cell lines are resistant to mitochondrial-depolarization-induced apoptosis
-
Zhao M, Mydlarz WK, Zhou S, Califano J (2008). Head and neck cancer cell lines are resistant to mitochondrial-depolarization-induced apoptosis. ORL J Otorhinolaryngol Relat Spec 70: 257-263.
-
(2008)
ORL J Otorhinolaryngol Relat Spec
, vol.70
, pp. 257-263
-
-
Zhao, M.1
Mydlarz, W.K.2
Zhou, S.3
Califano, J.4
-
90
-
-
60649116625
-
Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation
-
Zhou X, Munger K (2009). Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation. Virology 385: 192-197.
-
(2009)
Virology
, vol.385
, pp. 192-197
-
-
Zhou, X.1
Munger, K.2
-
91
-
-
0033573795
-
Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein
-
Zwerschke W, Mazurek S, Massimi P, Banks L, Eigenbrodt E, Jansen-Durr P (1999). Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein. Proc Natl Acad Sci USA 96: 1291-1296.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1291-1296
-
-
Zwerschke, W.1
Mazurek, S.2
Massimi, P.3
Banks, L.4
Eigenbrodt, E.5
Jansen-Durr, P.6
|