Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector

Gene Therapy

Volumn 9, Issue 1, 2002, Pages 2-11

  Ma, H I ^a,b,c   Lin, S Z ^b   Chiang, Y H ^b   Li, J ^a   Chen, S L ^c   Tsao, Y P ^d   Xiao, X ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Adeno associated viral (AAV) vector; Angiostatin gene; Antiangiogenesis; C6 glioma cells; Gene therapy

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ANTINEOPLASTIC AGENT; THYMIDINE KINASE; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CANCER; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; GENE EXPRESSION; GENE THERAPY; GLIOMA CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANGIOGENESIS INHIBITORS; ANGIOSTATINS; ANIMALS; BRAIN NEOPLASMS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GLIOMA; INJECTIONS, INTRALESIONAL; MALE; MODELS, ANIMAL; NEOPLASM TRANSPLANTATION; PEPTIDE FRAGMENTS; PLASMINOGEN; RATS; RATS, WISTAR; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSFECTION; TUMOR CELLS, CULTURED;

ADENO-ASSOCIATED VIRUS; ANIMALIA; DNA VIRUSES; RATTUS NORVEGICUS;

EID: 85047699234     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301616     Document Type: Article

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