Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice

Molecular Therapy

Volumn 3, Issue 2, 2001, Pages 186-196

  Scappaticci, Frank A ^a   Smith, Richard ^b   Pathak, Anjali ^b   Schloss, Derrick ^b   Lum, Bert ^b   Cao, Yihai ^c   Johnson, Frances ^b   Engleman, Edgar G ^a   Nolan, Garry P ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Angiogenesis inhibitor; Endothelial cells; Gene therapy; Leukemia; Melanoma

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ENDOSTATIN; RECOMBINANT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENICITY; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG RESEARCH; ENDOTHELIUM CELL; FEMALE; GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA; LONG TERM CARE; MELANOMA; MITOSIS INHIBITION; MOUSE; NONHUMAN; RETROVIRUS; UMBILICAL VEIN;

ANIMALIA; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 0034984653     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0243     Document Type: Article

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