메뉴 건너뛰기




Volumn 71, Issue 7, 1997, Pages 5236-5243

Role for highly regulated rep gene expression in adeno-associated virus vector production

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

EID: 0030959261     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.7.5236-5243.1997     Document Type: Article
Times cited : (178)

References (57)
  • 1
    • 0025958280 scopus 로고
    • Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells
    • Antoni, B. A., A. B. Rabson, I. L. Miller, J. P. Trempe, N. Chejanovsky, and B. J. Carter. 1991. Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells. J. Virol. 65:396-404.
    • (1991) J. Virol. , vol.65 , pp. 396-404
    • Antoni, B.A.1    Rabson, A.B.2    Miller, I.L.3    Trempe, J.P.4    Chejanovsky, N.5    Carter, B.J.6
  • 2
    • 0024428509 scopus 로고
    • Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein
    • Beaton, A., P. Palumbo, and K. I. Berns. 1989. Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein. J. Virol. 63:4450-4454.
    • (1989) J. Virol. , vol.63 , pp. 4450-4454
    • Beaton, A.1    Palumbo, P.2    Berns, K.I.3
  • 3
    • 0001999560 scopus 로고
    • Parvoviridae and their replication
    • B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. M. Monath, and B. Roizman (ed.), 2nd ed. Raven Press, New York, N.Y.
    • Berns, K. I. 1990. Parvoviridae and their replication, p. 1743-1763. In B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. M. Monath, and B. Roizman (ed.), Virology, vol. 2, 2nd ed. Raven Press, New York, N.Y.
    • (1990) Virology , vol.2 , pp. 1743-1763
    • Berns, K.I.1
  • 4
    • 0000595683 scopus 로고    scopus 로고
    • Parvoviridae: The viruses and their replication
    • B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), 3rd ed. Lippincott-Raven, Philadelphia, Pa.
    • Berns, K. I. 1996. Parvoviridae: the viruses and their replication, p. 2173-2220. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, vol. 2, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
    • (1996) Virology , vol.2 , pp. 2173-2220
    • Berns, K.I.1
  • 5
    • 0023081188 scopus 로고
    • Adeno-associated viruses: An update
    • Berns, K. I., and R. A. Bohenzky. 1987. Adeno-associated viruses: an update. Adv. Virus Res. 32:243-306.
    • (1987) Adv. Virus Res. , vol.32 , pp. 243-306
    • Berns, K.I.1    Bohenzky, R.A.2
  • 6
    • 0029552248 scopus 로고
    • Adenovirus and adeno-associated virus as vectors for gene therapy
    • Berns, K. I., and C. Giraud. 1995. Adenovirus and adeno-associated virus as vectors for gene therapy. Ann. N. Y. Acad. Sci. 772:95-104.
    • (1995) Ann. N. Y. Acad. Sci. , vol.772 , pp. 95-104
    • Berns, K.I.1    Giraud, C.2
  • 7
    • 0020570512 scopus 로고
    • Properties of an adenovirus type 2 mutant, Ad2dl807, having a deletion near the right-hand genome terminus: Failure to help AAV replication
    • Carter, B. J., C. J. Marcus-Sekura, C. A. Laughlin, and G. Ketner. 1983. Properties of an adenovirus type 2 mutant, Ad2dl807, having a deletion near the right-hand genome terminus: failure to help AAV replication. Virology 126:505-516.
    • (1983) Virology , vol.126 , pp. 505-516
    • Carter, B.J.1    Marcus-Sekura, C.J.2    Laughlin, C.A.3    Ketner, G.4
  • 8
    • 0024442216 scopus 로고
    • Mutagenesis of an AUG codon in the adeno-associated virus rep gene: Effects on viral DNA replication
    • Chejanovsky, N., and B. J. Carter. 1989. Mutagenesis of an AUG codon in the adeno-associated virus rep gene: effects on viral DNA replication. Virology 173:120-128.
    • (1989) Virology , vol.173 , pp. 120-128
    • Chejanovsky, N.1    Carter, B.J.2
  • 9
    • 0030001373 scopus 로고    scopus 로고
    • Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor
    • Dobner, T., N. Horikoshi, F. S. Rubenwol, and T. Shenk. 1996. Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science 272:1470-1473.
    • (1996) Science , vol.272 , pp. 1470-1473
    • Dobner, T.1    Horikoshi, N.2    Rubenwol, F.S.3    Shenk, T.4
  • 10
    • 0029923638 scopus 로고    scopus 로고
    • Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
    • Ferrari, F. K., T. Samulski, T. Shenk, and R. J. Samulski. 1996. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J. Virol. 70:3227-3234.
    • (1996) J. Virol. , vol.70 , pp. 3227-3234
    • Ferrari, F.K.1    Samulski, T.2    Shenk, T.3    Samulski, R.J.4
  • 11
    • 0029655894 scopus 로고    scopus 로고
    • Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis
    • Fisher, K. J., G. P. Gao, M. D. Weitzman, R. DeMatteo, J. F. Burda, and J. M. Wilson. 1996. Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. J. Virol. 70:520-532.
    • (1996) J. Virol. , vol.70 , pp. 520-532
    • Fisher, K.J.1    Gao, G.P.2    Weitzman, M.D.3    DeMatteo, R.4    Burda, J.F.5    Wilson, J.M.6
  • 12
    • 0028534879 scopus 로고
    • Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration
    • Flotte, T. R., S. A. Afione, and P. L. Zeitlin. 1994. Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration. Am. J. Respir. Cell Mol. Biol. 11:517-521.
    • (1994) Am. J. Respir. Cell Mol. Biol. , vol.11 , pp. 517-521
    • Flotte, T.R.1    Afione, S.A.2    Zeitlin, P.L.3
  • 13
    • 0028796523 scopus 로고
    • An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction
    • Flotte, T. R., X. Barraza-Ortiz, R. Solow, S. A. Afione, B. J. Carter, and W. B. Guggino. 1995. An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction. Gene Ther. 2:29-37.
    • (1995) Gene Ther. , vol.2 , pp. 29-37
    • Flotte, T.R.1    Barraza-Ortiz, X.2    Solow, R.3    Afione, S.A.4    Carter, B.J.5    Guggino, W.B.6
  • 14
    • 0029151404 scopus 로고
    • Adeno-associated virus vectors for gene therapy
    • Flotte, T. R., and B. J. Carter. 1995. Adeno-associated virus vectors for gene therapy. Gene Ther. 2:357-362.
    • (1995) Gene Ther. , vol.2 , pp. 357-362
    • Flotte, T.R.1    Carter, B.J.2
  • 15
    • 0028033782 scopus 로고
    • Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence
    • Giraud, C., E. Winocour, and K. I. Berns. 1994. Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence. Proc. Natl. Acad. Sci. USA 91:10039-10043.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10039-10043
    • Giraud, C.1    Winocour, E.2    Berns, K.I.3
  • 16
    • 0024345808 scopus 로고
    • The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins
    • Gorman, C. M., D. Gies, G. McCray, and M. Huang. 1989. The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins. Virology 171:377-385.
    • (1989) Virology , vol.171 , pp. 377-385
    • Gorman, C.M.1    Gies, D.2    McCray, G.3    Huang, M.4
  • 17
    • 0025299743 scopus 로고
    • The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplification
    • Heilbronn, R., A. Burkle, S. Stephan, and H. zur Hausen. 1990. The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplification. J. Virol. 64:3012-3018.
    • (1990) J. Virol. , vol.64 , pp. 3012-3018
    • Heilbronn, R.1    Burkle, A.2    Stephan, S.3    Zur Hausen, H.4
  • 18
    • 0028356554 scopus 로고
    • Down-regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78
    • Hermonat, P. L. 1994. Down-regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78. Cancer Lett. 81:129-136.
    • (1994) Cancer Lett. , vol.81 , pp. 129-136
    • Hermonat, P.L.1
  • 19
    • 0014202537 scopus 로고
    • Selective extraction of polyoma DNA from infected mouse cultures
    • Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cultures. J. Mol. Biol. 26:365-369.
    • (1967) J. Mol. Biol. , vol.26 , pp. 365-369
    • Hirt, B.1
  • 20
    • 0029119779 scopus 로고
    • Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters
    • Horer, M., S. Weger, K. Butz, F. Hoppe-Seyler, C. Geisen, and J. A. Kleinschmidt. 1995. Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters. J. Virol. 69:5485-5496.
    • (1995) J. Virol. , vol.69 , pp. 5485-5496
    • Horer, M.1    Weger, S.2    Butz, K.3    Hoppe-Seyler, F.4    Geisen, C.5    Kleinschmidt, J.A.6
  • 21
    • 0026501651 scopus 로고
    • Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells
    • Hunter, L. A., and R. J. Samulski. 1992. Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells. J. Virol. 66: 317-324.
    • (1992) J. Virol. , vol.66 , pp. 317-324
    • Hunter, L.A.1    Samulski, R.J.2
  • 22
    • 0028169741 scopus 로고
    • Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
    • Kaplitt, M. G., P. Leone, R. J. Samulski, X. Xiao, D. W. Pfaff, K. L. O'Malley, and M. J. During. 1994. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat. Gene. 8:148-154.
    • (1994) Nat. Gene. , vol.8 , pp. 148-154
    • Kaplitt, M.G.1    Leone, P.2    Samulski, R.J.3    Xiao, X.4    Pfaff, D.W.5    O'Malley, K.L.6    During, M.J.7
  • 25
    • 0023907237 scopus 로고
    • The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells
    • Labow, M. A., and K. I. Berns. 1988. The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells. J. Virol. 62:1705-1712.
    • (1988) J. Virol. , vol.62 , pp. 1705-1712
    • Labow, M.A.1    Berns, K.I.2
  • 26
    • 0023118717 scopus 로고
    • Adeno-associated virus gene expression inhibits cellular transformation by heterologous genes
    • Labow, M. A., L. H. Graf, Jr., and K. I. Berns. 1987. Adeno-associated virus gene expression inhibits cellular transformation by heterologous genes. Mol. Cell. Biol. 7:1320-1325.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1320-1325
    • Labow, M.A.1    Graf Jr., L.H.2    Berns, K.I.3
  • 27
    • 0022451185 scopus 로고
    • Positive and negative autoregulation of the adeno-associated virus type 2 genome
    • Labow, M. A., P. L. Hermonat, and K. I. Berns. 1986. Positive and negative autoregulation of the adeno-associated virus type 2 genome. J. Virol. 60: 251-258.
    • (1986) J. Virol. , vol.60 , pp. 251-258
    • Labow, M.A.1    Hermonat, P.L.2    Berns, K.I.3
  • 28
    • 0020086215 scopus 로고
    • Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus
    • Laughlin, C. A., N. Jones, and B. J. Carter. 1982. Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus. J. Virol. 41:868-876.
    • (1982) J. Virol. , vol.41 , pp. 868-876
    • Laughlin, C.A.1    Jones, N.2    Carter, B.J.3
  • 29
    • 0028877865 scopus 로고
    • Adenovirus E1A proteins interact with the cellular YY1 transcription factor
    • Lewis, B. A., G. Tullis, E. Seto, N. Horikoshi, R. Weinmann, and T. Shenk. 1995. Adenovirus E1A proteins interact with the cellular YY1 transcription factor. J. Virol. 69:1628-1636.
    • (1995) J. Virol. , vol.69 , pp. 1628-1636
    • Lewis, B.A.1    Tullis, G.2    Seto, E.3    Horikoshi, N.4    Weinmann, R.5    Shenk, T.6
  • 30
    • 1842362220 scopus 로고    scopus 로고
    • Unpublished observations
    • Li, J., and X. Xiao. Unpublished observations.
    • Li, J.1    Xiao, X.2
  • 31
    • 0025946426 scopus 로고
    • Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein
    • McCarty, D. M., M. Christensen, and N. Muzyczka. 1991. Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein. J. Virol. 65:2936-2945.
    • (1991) J. Virol. , vol.65 , pp. 2936-2945
    • McCarty, D.M.1    Christensen, M.2    Muzyczka, N.3
  • 32
    • 0030003480 scopus 로고    scopus 로고
    • Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector
    • McCown, T. J., X. Xiao, J. Li, G. R. Breese, and R. J. Samulski. 1996. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Res. 713:99-107.
    • (1996) Brain Res. , vol.713 , pp. 99-107
    • McCown, T.J.1    Xiao, X.2    Li, J.3    Breese, G.R.4    Samulski, R.J.5
  • 33
    • 0013021037 scopus 로고
    • In vitro replication of adeno-associated virus DNA
    • Muzyczka, N. 1991. In vitro replication of adeno-associated virus DNA. Semin. Virol. 2:281-290.
    • (1991) Semin. Virol. , vol.2 , pp. 281-290
    • Muzyczka, N.1
  • 34
    • 0026525713 scopus 로고
    • Use of adeno-associated virus as a general transduction vector for mammalian cells
    • Muzyczka, N. 1992. Use of adeno-associated virus as a general transduction vector for mammalian cells. Curr. Top. Microbiol. Immunol. 158:97-129.
    • (1992) Curr. Top. Microbiol. Immunol. , vol.158 , pp. 97-129
    • Muzyczka, N.1
  • 36
    • 0031014018 scopus 로고    scopus 로고
    • The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection
    • Pereira, D. J., D. M. McCarty, and N. Muzyczka. 1997. The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection. J. Virol. 71:1079-1088.
    • (1997) J. Virol. , vol.71 , pp. 1079-1088
    • Pereira, D.J.1    McCarty, D.M.2    Muzyczka, N.3
  • 37
    • 0028060363 scopus 로고
    • Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors
    • Podsakoff, G., K. K. Wong, Jr., and S. Chatterjee. 1994. Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors. J. Virol. 68:5656-5666.
    • (1994) J. Virol. , vol.68 , pp. 5656-5666
    • Podsakoff, G.1    Wong Jr., K.K.2    Chatterjee, S.3
  • 38
    • 0011363436 scopus 로고
    • Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein
    • Rice, A. P., and M. B. Mathews. 1988. Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein. Proc. Natl. Acad. Sci. USA 85:4200-4204.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4200-4204
    • Rice, A.P.1    Mathews, M.B.2
  • 40
    • 0024311525 scopus 로고
    • Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression
    • Samulski, R. J., L. S. Chang, and T. Shenk. 1989. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J. Virol. 63:3822-3828.
    • (1989) J. Virol. , vol.63 , pp. 3822-3828
    • Samulski, R.J.1    Chang, L.S.2    Shenk, T.3
  • 41
    • 0023949464 scopus 로고
    • Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs
    • Samulski, R. J., and T. Shenk. 1988. Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. J. Virol. 62:206-210.
    • (1988) J. Virol. , vol.62 , pp. 206-210
    • Samulski, R.J.1    Shenk, T.2
  • 42
    • 0020586937 scopus 로고
    • Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV
    • Samulski, R. J., A. Srivastava, K. I. Berns, and N. Muzyczka. 1983. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell 33:135-143.
    • (1983) Cell , vol.33 , pp. 135-143
    • Samulski, R.J.1    Srivastava, A.2    Berns, K.I.3    Muzyczka, N.4
  • 44
    • 0025943945 scopus 로고
    • Transcriptional repression by YY1, a human GL1-Kruppel-related protein, and relief of repression by adenovirus E1A protein
    • Shi, Y., E. Seto, L. S. Chang, and T. Shenk. 1991. Transcriptional repression by YY1, a human GL1-Kruppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67:377-388.
    • (1991) Cell , vol.67 , pp. 377-388
    • Shi, Y.1    Seto, E.2    Chang, L.S.3    Shenk, T.4
  • 45
    • 0022765969 scopus 로고
    • Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product
    • Tratschin, J. D., J. Tal, and B. J. Carter. 1986. Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product. Mol. Cell. Biol. 6:2884-2894.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2884-2894
    • Tratschin, J.D.1    Tal, J.2    Carter, B.J.3
  • 46
    • 0023877296 scopus 로고
    • Regulation of adeno-associated virus gene expression in 293 cells: Control of mRNA abundance and translation
    • Trempe, J. P., and B. J. Carter. 1988. Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation. J. Virol. 62:68-74.
    • (1988) J. Virol. , vol.62 , pp. 68-74
    • Trempe, J.P.1    Carter, B.J.2
  • 47
    • 0021889316 scopus 로고
    • Adenovirus E1a proteins repress transcription from the SV40 early promoter
    • Velcich, A., and E. Ziff. 1985. Adenovirus E1a proteins repress transcription from the SV40 early promoter. Cell 40:705-716.
    • (1985) Cell , vol.40 , pp. 705-716
    • Velcich, A.1    Ziff, E.2
  • 48
    • 0031041173 scopus 로고    scopus 로고
    • Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products
    • 47a. Vincent, K. A., S. T. Pirano, and S. C. Wadsworth. 1997. Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products. J. Virol. 71:1897-1905.
    • (1997) J. Virol. , vol.71 , pp. 1897-1905
    • Vincent, K.A.1    Pirano, S.T.2    Wadsworth, S.C.3
  • 49
    • 0029888985 scopus 로고    scopus 로고
    • In vitro replication of adeno-associated virus DNA: Enhancement by extracts from adenovirus-infected HeLa cells
    • 47b. Ward, P., and K. I. Berns. 1996. In vitro replication of adeno-associated virus DNA: enhancement by extracts from adenovirus-infected HeLa cells. J. Virol. 70:4495-4501.
    • (1996) J. Virol. , vol.70 , pp. 4495-4501
    • Ward, P.1    Berns, K.I.2
  • 50
    • 0028307303 scopus 로고
    • Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA
    • Weitzman, M. D., S. R. Kyostio, R. M. Kotin, and R. A. Owens. 1994. Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA. Proc. Natl. Acad. Sci. USA 91:5808-5812.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5808-5812
    • Weitzman, M.D.1    Kyostio, S.R.2    Kotin, R.M.3    Owens, R.A.4
  • 52
    • 0027762717 scopus 로고
    • Adeno-associated virus (AAV) vectors for gene transfer
    • Xiao, X., W. DeVlaminick, and J. Monahan. 1993. Adeno-associated virus (AAV) vectors for gene transfer. Adv. Drug Delivery Rev. 12:201-215.
    • (1993) Adv. Drug Delivery Rev. , vol.12 , pp. 201-215
    • Xiao, X.1    DeVlaminick, W.2    Monahan, J.3
  • 54
    • 0029843596 scopus 로고    scopus 로고
    • Long-term and efficient in vivo gene transfer into muscle tissue of immunocompetent mice with an rAAV vector
    • Xiao, X., J. Li, and R. J. Samulski. 1996. Long-term and efficient in vivo gene transfer into muscle tissue of immunocompetent mice with an rAAV vector. J. Virol. 70:8098-8108.
    • (1996) J. Virol. , vol.70 , pp. 8098-8108
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 55
    • 0031016643 scopus 로고    scopus 로고
    • A novel 165-base-pair terminal repeat sequence is the sole cis requirement for adeno-associated virus life cycle
    • Xiao, X., W. Xiao, J. Li, and R. J. Samulski. 1997. A novel 165-base-pair terminal repeat sequence is the sole cis requirement for adeno-associated virus life cycle. J. Virol. 71:941-948.
    • (1997) J. Virol. , vol.71 , pp. 941-948
    • Xiao, X.1    Xiao, W.2    Li, J.3    Samulski, R.J.4
  • 56
    • 0028926589 scopus 로고
    • Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins
    • Yang, Q., F. Chen, J. Ross, and J. P. Trempe. 1995. Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins. Virology 207:246-250.
    • (1995) Virology , vol.207 , pp. 246-250
    • Yang, Q.1    Chen, F.2    Ross, J.3    Trempe, J.P.4
  • 57
    • 0028228449 scopus 로고
    • Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins
    • Yang, Q., F. Chen, and J. P. Trempe. 1994. Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins. J. Virol. 68:4847-4856.
    • (1994) J. Virol. , vol.68 , pp. 4847-4856
    • Yang, Q.1    Chen, F.2    Trempe, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.