HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma

Gene Therapy

Volumn 7, Issue 17, 2000, Pages 1483-1490

  Moriuchi, S ^a,b   Krisky, D M ^a   Marconi, P C ^a   Tamura, M ^a   Shimizu, K ^b   Yoshimine, T ^b   Cohen, J B ^a   Glorioso, J C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Cytotoxicity; Ganciclovir; Gene therapy; Glioblastoma; Herpes simplex virus; HSV thymidine kinase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA GALACTOSIDASE; GANCICLOVIR; IMMEDIATE EARLY PROTEIN; THYMIDINE KINASE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN TUMOR; CANCER SURVIVAL; CANCER THERAPY; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CLONING VECTOR; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; GENE EXPRESSION; GENE REPLICATION; GENE THERAPY; GLIOSARCOMA; HERPES SIMPLEX VIRUS; IMMEDIATE EARLY GENE; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SUICIDE GENE; TUMOR CELL; VIRUS GENE;

ANIMALIA; DNA VIRUSES; HERPES; SIMPLEXVIRUS;

EID: 0033800317     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301265     Document Type: Article

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