Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

Human Molecular Genetics

Volumn 17, Issue 11, 2008, Pages 1540-1555

  Tang, Guomei ^a   Yue, Zhenyu ^b   Talloczy, Zsolt ^a   Hagemann, Tracy ^c   Cho, Woosung ^c   Messing, Albee ^c   Sulzer, David I ^a   Goldman, James E ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SYNAPTOPHYSIN;

ALEXANDER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CHILD; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALEXANDER DISEASE; ANIMALS; ASTROCYTES; AUTOPHAGY; BRAIN; CELL LINE, TUMOR; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MICE; MICE, MUTANT STRAINS; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VACUOLES;

MAMMALIA;

EID: 44349107112     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn042     Document Type: Article

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