Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease

Journal of Proteome Research

Volumn 15, Issue 7, 2016, Pages 2265-2282

  Heaven, Michael R ^a   Flint, Daniel ^a   Randall, Shan M ^c   Sosunov, Alexander A ^d   Wilson, Landon ^b   Barnes, Stephen ^b   Goldman, James E ^e   Muddiman, David C ^c   Brenner, Michael ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d Department of Neurosurgery ^*  (United States)

^e Department of Medicine   (United States)

Author keywords

Alexander disease; astrocyte; mass spectrometry (MS); neurodegenerative disease; protein aggregates; proteomics; Rosenthal fiber; stress granules

Indexed keywords

CYCLIN D2; PROTEIN AGGREGATE; RECEPTOR FOR ACTIVATED C KINASE 1; RNA HELICASE; ROSENTHAL FIBER; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DDX3X PROTEIN, HUMAN; DDX3X PROTEIN, MOUSE; DEAD BOX PROTEIN; GNB2-RS1 PROTEIN, MOUSE; GNB2L1 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROPEPTIDE; PROTEOME; TUMOR PROTEIN;

ADOLESCENT; ADULT; ALEXANDER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFANT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MIDDLE AGED; MOUSE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; SCHOOL CHILD; TANDEM MASS SPECTROMETRY; ANIMAL; ASTROCYTE; PROTEINOSIS;

ALEXANDER DISEASE; ANIMALS; ASTROCYTES; CYCLIN D2; DEAD-BOX RNA HELICASES; GTP-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; NEOPLASM PROTEINS; NEUROPEPTIDES; PROTEIN AGGREGATES; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEOME; RECEPTORS, CELL SURFACE; RNA HELICASES;

EID: 84977090449     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.6b00316     Document Type: Article

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