Engineering human cells and tissues through pluripotent stem cells

Current Opinion in Biotechnology

Volumn 40, Issue , 2016, Pages 133-138

  Jones, Jeffrey R ^a   Zhang, Su Chun ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; HISTOLOGY; STEM CELLS; TISSUE;

CELLULAR FUNCTION; DIFFERENTIATED CELLS; DIRECTED DIFFERENTIATIONS; FUNCTIONAL CELLS; HUMAN CELLS; ORGANOIDS; PLURIPOTENT STEM CELLS; SPONTANEOUS GENERATION;

CELL ENGINEERING;

CELL AGGREGATION; CELL DIFFERENTIATION; CELL ENGINEERING; CELL FUNCTION; CELL MATURATION; CELL POPULATION; CELL SPECIFICITY; CELLS BY BODY ANATOMY; DNA MODIFICATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EPIGENETICS; GENETIC ENGINEERING; GERM LAYER; HISTOGENESIS; HUMAN; INTERNEURON; MEDICAL TECHNOLOGY; NEURAL STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; CYTOLOGY; GENETICS; PROCEDURES; RNA EDITING;

CELL DIFFERENTIATION; HUMANS; PLURIPOTENT STEM CELLS; RNA EDITING; TISSUE ENGINEERING;

EID: 84962808625     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2016.03.010     Document Type: Review

References (53)

1. Thomson J.A. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.
2. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
3. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., Nie J., Jonsdottir G.A., Ruotti V., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
4. Zhang S., Wernig M., Duncan I.D., Thomson J.A. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 2001, 19:1129-1133.
5. Oldershaw R.A., Baxter M.A., Lowe E.T., Bates N., Grady L.M., Soncin F., Brison D.R., Hardingham T.E., Kimber S.J. Directed differentiation of human embryonic stem cells toward chondrocytes. Nat Biotechnol 2010, 28:1187-1194.
6. Wang D., Haviland D.L., Burns A.R., Zsigmond E., Wetsel R.A. A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 2007, 104:4449-4454.
7. Pagliuca F.W., Millman J.R., Gürtler M., Segel M., Van Dervort A., Ryu J.H., Peterson Q.P., Greiner D., Melton D.A. Generation of functional human pancreatic β cells in vitro. Cell 2014, 159:428-439.
8. Lamba D.A., Karl M.O., Ware C.B., Reh T.A. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci USA 2006, 103:12769-12774.
9. Kriks S., Shim J.W., Piao J., Ganat Y.M., Wakeman D.R., Xie Z., Carrillo-Reid L., Auyeung G., Antonacci C., Buch A., et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011, 480:547-551.
10. Li X.J., Du Z.W., Zarnowska E.D., Pankratz M., Hansen L.O., Pearce R.A., Zhang S.C. Specification of motoneurons from human embryonic stem cells. Nat Biotechnol 2005, 23:215-221.
11. Liu Y., Weick J.P., Liu H., Krencik R., Zhang X., Ma L., Zhou G., Ayala M., Zhang S.C. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nat Biotechnol 2013, 31:440-447.
12. Krencik R., Weick J.P., Liu Y., Zhang Z.J., Zhang S.C. Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nat Biotechnol 2011, 29:528-534.
13. Lu J., Zhong X., Liu H., Hao L., Huang C.T.-L., Sherafat M.A., Jones J., Ayala M., Li L., Zhang S.C. Generation of serotonin neurons from human pluripotent stem cells. Nat Biotechnol 2015, 34:89-94.
14. Hu B.Y., Weick J.P., Yu J., Ma L.X., Zhang X.Q., Thomson J.A., Zhang S.C. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci USA 2010, 107:4335-4340.
15. Lamb T.M., Knecht A.K., Smith W.C., Stachel S.E., Economides A.N., Stahl N., Yancopolous G.D., Harland R.M. Neural induction by the secreted polypeptide noggin. Science 1993, 262:713-718.
16. Hemmati-Brivanlou A., Kelly O.G., Melton D.A. Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 1994, 77:283-295.
17. Sasai Y., Lu B., Steinbeisser H., Geissert D., Gont L.K., De Robertis E.M. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 1994, 79:779-790.
18. Elkabetz Y., Panagiotakos G., Al Shamy G., Socci N.D., Tabar V., Studer L. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev 2008, 22:152-165.
19. Smith J.R., Vallier L., Lupo G., Alexander M., Harris W.A., Pedersen R.A. Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Dev Biol 2008, 313:107-117.
20. LaVaute T.M., Yoo Y.D., Pankratz M.T., Weick J.P., Gerstner J.R., Zhang S.C. Regulation of neural specification from human embryonic stem cells by BMP and FGF. Stem Cells 2009, 27:1741-1749.
21. Chambers S.M., Fasano C.A., Papapetrou E.P., Tomishima M., Sadelain M., Studer L. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol 2009, 27:275-280.
22. Petersen C.P., Reddien P.W. Wnt signaling and the polarity of the primary body axis. Cell 2009, 139:1056-1068.
23. Placzek M. The role of the notochord and floor plate in inductive interactions. Curr Opin Genet Dev 1995, 5:499-506.
24. Jessell T.M. Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet 2000, 1:20-29.
25. Kirkeby A., Grealish S., Wolf D.A., Nelander J., Wood J., Lundblad M., Lindvall O., Parmar M. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Rep 2012, 1:703-714.
26. Xi J., Liu Y., Liu H., Chen H., Emborg M.E., Zhang S.C. Specification of midbrain dopamine neurons from primate pluripotent stem cells. Stem Cells 2012, 30:1655-1663.
27. Li X.J., Zhang X., Johnson M.A., Wang Z.B., Lavaute T., Zhang S.C. Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells. Development 2009, 136:4055-4063.
28. Vazin T., Ball K.A., Lu H., Park H., Ataeijannati Y., Head-Gordon T., Poo M., Schaffer D.V. Efficient derivation of cortical glutamatergic neurons from human pluripotent stem cells: a model system to study neurotoxicity in Alzheimer's disease. Neurobiol Dis 2014, 62:62-72.
29. Ma L., Hu B., Liu Y., Vermilyea S.C., Liu H., Gao L., Sun Y., Zhang X., Zhang S.C. Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell Stem Cell 2012, 10:455-464.
30. Liu Y., Liu H., Sauvey C., Yao L., Zarnowska E.D., Zhang S.C. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nat Protoc 2013, 8:1670-1679.
31. Maroof A.M., Keros S., Tyson J.A., Ying S.W., Ganat Y.M., Merkle F.T., Liu B., Goulburn A., Stanley E.G., Elefanty A.G., et al. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 2013, 12:559-572.
32. Eiraku M., Takata N., Ishibashi H., Kawada M., Sakakura E., Okuda S., Sekiguchi K., Adachi T., Sasai Y. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 2011, 472:51-56.
33. 6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci USA 2005, 102:11331-11336.
34. Davis A.A., Matzuk M.M., Reh T.A. Activin A promotes progenitor differentiation into photoreceptors in rodent retina. Mol Cell Neurosci 2000, 15:11-21.
35. Nakano T., Ando S., Takata N., Kawada M., Muguruma K., Sekiguchi K., Saito K., Yonemura S., Eiraku M., Sasai Y. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 2012, 10:771-785.
36. Rakic P. Elusive radial glial cells: historical and evolutionary perspective. Glia 2003, 43:19-32.
37. Shi Y., Kirwan P., Smith J., Robinson H.P.C., Livesey F.J. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci 2012, 15:477-486. S1.
38. Lancaster M.A., Renner M., Martin C.A., Wenzel D., Bicknell L.S., Hurles M.E., Homfray T., Penninger J.M., Jackson A.P., Knoblich J.A. Cerebral organoids model human brain development and microcephaly. Nature 2013, 501:373-379.
39. Eiraku M., Watanabe K., Matsuo-Takasaki M., Kawada M., Yonemura S., Matsumura M., Wataya T., Nishiyama A., Muguruma K., Sasai Y. Self-organized formation of polarized cortical tissues from escs and its active manipulation by extrinsic signals. Cell Stem Cell 2008, 3:519-532.
40. Paşca A.M., Sloan S.A., Clarke L.E., Tian Y., Makinson C.D., Huber N., Kim C.H., Park J.Y., O'Rourke N.A., Nguyen K.D., et al. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat Methods 2015, 12:671-678.
41. Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
42. Civril F., Deimling T., de Oliveira Mann C.C., Ablasser A., Moldt M., Witte G., Hornung V., Hopfner K.P. Structural mechanism of cytosolic DNA sensing by cGAS. Nature 2013, 498:332-337.
43. Papayannakos C., Daniel R. Understanding lentiviral vector chromatin targeting: working to reduce insertional mutagenic potential for gene therapy. Gene Ther 2013, 20:581-588.
44. Yang L., Esvelt K.M., Aach J., Guell M., James E., Norville J.E., Church G.M. RNA-guided human genome engineering via Cas9. Science 2013, 339:823-826.
45. Cong L., Ran F.A., Cox D., Lin S., Barretto R., Habib N., Hsu P.D., Wu X., Jiang W., Marraffini L.A., et al. Multiplex genome engineering using CRISPR/Cas systems. Science 2013, 339:819-823.
46. Sanjana N.E., Cong L., Zhou Y., Cunniff M.M., Feng G., Zhang F. A transcription activator-like effector toolbox for genome engineering. Nat Protoc 2012, 7:171-192.
47. Schwank G., Koo B.K., Sasselli V., Dekkers J.F., Heo I., Demircan T., Sasaki N., Boymans S., Cuppen E., Van Der Ent C.K., et al. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 2013, 13:653-658.
48. Chen H., Qian K., Du Z., Cao J., Petersen A., Liu H., Blackbourn L.W., Huang C.L., Errigo A., Yin Y., et al. Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons. Cell Stem Cell 2014, 14:796-809.
49. Feng Q., Shabrani N., Thon J.N., Huo H., Thiel A., Machlus K.R., Kim K., Brooks J., Li F., Luo C., et al. Scalable generation of universal platelets from human induced pluripotent stem cells. Stem Cell Rep 2014, 3:817-831.
50. Chen Y.J., Xiong M., Dong Y., Haberman A., Liu H., Zhang S.C. Remote control of transplanted human neuron function in mice. Cell Stem Cell 2016, [in press].
51. Zhang Y., Pak C., Han Y., Ahlenius H., Zhang Z., Chanda S., Marro S., Patzke C., Acuna C., Covy J., et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 2013, 78:785-798.
52. Miller J.D., Ganat Y.M., Kishinevsky S., Bowman R.L., Liu B., Tu E.Y., Mandal P.K., Vera E., Shim J., Kriks S., et al. Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell 2013, 13:691-705.
53. Du Z.-W., Chen H., Liu H., Lu J., Qian K., Huang C.-L., Zhong X., Fan F., Zhang S.-C. Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells. Nat Commun 2015, 6:6626.