Nitric oxide mediates glial-induced neurodegeneration in Alexander disease

Nature Communications

Volumn 6, Issue , 2015, Pages

  Wang, Liqun ^a   Hagemann, Tracy L ^b   Kalwa, Hermann ^c   Michel, Thomas ^c   Messing, Albee ^b   Feany, Mel B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 3; NITRIC OXIDE; PROTEIN P53; GLIAL FIBRILLARY ACIDIC PROTEIN;

APOPTOSIS; CELLS AND CELL COMPONENTS; CHEMICAL CUE; DNA; HOMINID; INJURY; NERVOUS SYSTEM DISORDER; NITRIC OXIDE; TOXICITY;

ALEXANDER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; FRUIT FLY MODEL; GLIA; GLIA CELL; MACROGLIA; NERVE CELL; NERVE DEGENERATION; NEUROMODULATION; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; UPREGULATION; ADOLESCENT; ADULT; ANIMAL; CHILD; CONFOCAL MICROSCOPY; DEGENERATIVE DISEASE; DISEASE MODEL; DROSOPHILA; FEMALE; GENETICS; HUMAN; INFANT; MALE; METABOLISM; METACHROMATIC LEUKODYSTROPHY; MOUSE; PATHOLOGY; PRESCHOOL CHILD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; TRANSGENIC ORGANISM; TUNEL ASSAY; WESTERN BLOTTING; YOUNG ADULT;

ADOLESCENT; ADULT; ALEXANDER DISEASE; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELL DEATH; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; DROSOPHILA; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IN SITU NICK-END LABELING; INFANT; LEUKODYSTROPHY, METACHROMATIC; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEURONS; NITRIC OXIDE; ORGANISMS, GENETICALLY MODIFIED; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84948392102     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9966     Document Type: Article

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