HIV-1 env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

eLife

Volumn 7, Issue , 2018, Pages

  Ma, Xiaochu ^a   Lu, Maolin ^a   Gorman, Jason ^b   Terry, Daniel S ^c   Hong, Xinyu ^a   Zhou, Zhou ^c   Zhao, Hong ^c   Altman, Roger B ^c   Arthos, James ^b   Blanchard, Scott C ^c   Kwong, Peter D ^b   Munro, James B ^d   Mothes, Walther ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120; VIRUS GLYCOPROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; PROTEIN BINDING; VIRUS ENVELOPE PROTEIN;

ARTICLE; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; HIDDEN MARKOV MODEL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY; VIRUS ISOLATION; VIRUS NEUTRALIZATION; CHEMISTRY; IMMUNOLOGY; METABOLISM; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNIT; VIRION;

CD4 ANTIGENS; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; VIRION;

EID: 85045694121     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.34271     Document Type: Article

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